Results 61 to 70 of about 4,338 (258)
Advanced Science, EarlyView.This review examines emerging combination immunotherapy strategies tailored to distinct tumor microenvironments and highlights next‐generation biomarkers that guide response prediction and treatment personalization. It integrates lessons from unsuccessful trials, addresses toxicity challenges, and outlines approaches for early biomarker discovery and ...
Asmita Pandey +6 more
wiley +1 more source
Symmetry, Integrability and Geometry: Methods and ApplicationsWe describe the tropical curves in toric varieties and define the tropical Gromov-Witten invariants. We introduce amplitudes for the higher topological quantum mechanics (HTQM) on special trees and show that the amplitudes are equal to the tropical Gromov-Witten invariants.
Losev, Andrey, Lysov, Vyacheslav
openaire +3 more sources
Global Nitrogen Deposition Promotes Carbon Sink Formation in Terrestrial Ecosystems
Advanced Science, EarlyView.Nitrogen deposition alleviates ecosystem N limitation and enhances carbon sinks. Using 829 observations, we show 36% of deposited N is retained globally (39.15 Tg N yr−1), with distinct NHx and NOy contributions. This retention drives a terrestrial C sink of 0.88 Pg C yr−1 (25.48%), highlighting the importance of pool‐specific C:N stoichiometry ...
Lei Li +6 more
wiley +1 more source
Advanced Science, EarlyView.ABSTRACT Anti‐NMDAR encephalitis (NMDARE) is an autoantibody‐mediated disorder characterized by seizures, movement disorders, neurocognitive deficits, and psychosis, but the complete phenotypic heterogeneity, and outcomes are incompletely understood in children.
Alexander J. Sandweiss +9 more
wiley +1 more source
Mining disaster in instalments: the completion of the foundations for the modern health and safety system on the Witwatersrand gold mines 1930 -1939 [PDF]
, 1990 Paper presented at the Wits History Workshop: Structure and Experience in the Making of Apartheid, 6-10 February ...
Smith, Matthew
core
Advanced Science, EarlyView.In wild‐type cells, FIPV infection recruits CLTC to nsp3, facilitates DMV biogenesis and block autophagic flux to promote viral replication. CLTC knockout impairs autophagosome nucleation by reducing Beclin1–ATG14 complex expression. This disrupts the formation of autophagic precursor membranes, thereby preventing their hijacking by nsp3 for DMV ...
Juan Xu +9 more
wiley +1 more source
Novel long-acting brimonidine tartrate loaded-PCL/PVP nanofibers for versatile biomedical applications: fabrication, characterization and antimicrobial evaluation. [PDF]
RSC Adv, 2023 Salim SA +4 more
europepmc +1 more source
La lluita interna de les plantes enfront la intoxicació per alumini [PDF]
, 2009 Tot i l'origen natural de l'alumini, aquest metall pot dificultar seriosament la vida vegetal. Concretament, en aquells terrenys àcids d'àrees tropicals i subtropicals que solubilitzen l'alumini i faciliten que sigui absorbit per l'arrel de la planta. En
Barceló Coll, Juan
core +1 more source
Advanced Science, EarlyView.Prostate cancer remains a leading cause of male cancer death, yet screening cannot reliably identify aggressive disease, underscoring the need for tissue biomarkers. It is shown that primary tumors increase ER–plasma membrane junction signaling via STIM1/ORP5, whereas metastasis features their loss, Golgi dispersal, and rapid conversion of high‐mannose
Amanda J. Macke +14 more
wiley +1 more source
Advanced Science, EarlyView.This study develops neural bioprinted piezoelectric scaffolds which construct local “sensor‐effector” circuit, inspired by the skeletal interoception system. Upon US stimulation sensing and mechanoelectrical coupling by PLLA nanofibers, the incorporated DRG neurons effect through Ca2+ influx‐induced enhanced secretion and expression of CGRP.
Yingze Su +18 more
wiley +1 more source