Results 21 to 30 of about 310 (131)

Single‐Cell Annotation and Localization via Integrating Spatial Transcriptomics Maps the Mouse Ocular Atlas and RAO Dynamics

open access: yesAdvanced Science, EarlyView.
We developed the ASCAL pipeline, integrating complementary spatial transcriptomics, to construct a high‐fidelity mouse whole‐eye single‐cell atlas. Applying ASCAL to a retinal artery occlusion (RAO) model revealed spatially restricted immune activation localized to the ganglion cell layer and the selective depletion of a translationally active, outer ...
Chen Du   +11 more
wiley   +1 more source

Tropicamide ophthalmic solution reduces clozapine-induced sialorrhea: a case report

open access: yesPsychiatry and Clinical Psychopharmacology, 2017
Clozapine-induced sialorrhea (CIS) is a common, treatment-limiting, and stigmatizing side effect. All systemic agents that are used for CIS may increase clozapine side effects such as blood pressure changes, constipation, or arrhythmias or may have a ...
Ozge Kilic   +2 more
doaj   +1 more source

Acute lens opacity induced by different kinds of anesthetic drugs in mice [PDF]

open access: yesInternational Journal of Ophthalmology, 2019
AIM: To study whether specific anesthetic drugs or tear layer evaporation was primarily responsible for the acute cataract and what the change of lens structure is in anesthetized mice.
Xiao-Tong Li   +3 more
doaj   +1 more source

Eye‐Brain Neuroimmune Axis Enables Long‐Term Survival in Glioblastoma by Modulating Brain Immune Surveillance and Neuronal Excitability

open access: yesAdvanced Science, EarlyView.
The eye–brain neuroimmune axis triggers immune activation and disrupts pathological neuronal connectivity to extend glioblastoma survival. ABSTRACT As an anatomical extension of the central nervous system (CNS), the eye harbors rich neural and immune interfaces with the brain. However, the integrated immunological and neurological nexus between the eye
Mingyue Cui   +9 more
wiley   +1 more source

OBJECTIVE ACCOMMODATION RESPONSE VALUE (COMPLETENESS OF CYCLOPLEGIA) AFTER DIAGNOSTIC INSTILLATIONS OF DIVERSE MEDICATIONS

open access: yesРоссийский офтальмологический журнал, 2018
Today, a variety of medications are used in ophthalmology practice to o produce cycloplegia and mydriasis. Purpose: to compare the extent of cycloplegia by residual accommodation response after instillations of various medications. Materials and methods.
N. A. Tarasova   +3 more
doaj   +1 more source

Time-Course of Changes in Choroidal Thickness after Complete Mydriasis Induced by Compound Tropicamide in Children. [PDF]

open access: yesPLoS ONE, 2016
The aim of this study was to investigate the time-course of changes in choroidal thickness (ChT) following complete mydriasis induced by compound tropicamide.ChT was measured by OCT with the enhanced-depth imaging technique (Spectralis HRA+OCT ...
Zhouyue Li   +5 more
doaj   +1 more source

Evaluation of efficacy of intracameral lidocaine and tropicamide injection in manual small-incision cataract surgery: A prospective clinical study

open access: yesIndian Journal of Ophthalmology, 2022
Purpose: The study was conducted to evaluate efficacy of intracameral lidocaine hydrochloride 1% and tropicamide injection 0.02% for anaesthesia and mydriasis in manual small-incision cataract surgery (MSICS) and to report any adverse drug reaction ...
Ketaki T Bhat   +3 more
doaj   +1 more source

MAM‐Localized MANF Counteracts Microinflammatory Stress to Attenuate Mitochondrial Dysfunction and Cataractogenesis in High Myopia

open access: yesAdvanced Science, EarlyView.
Chronic microinflammation in high myopia suppresses MANF in lens epithelial cells. MANF normally resides within MAMs and promotes ubiquitin‐mediated degradation of the ER Ca2+ pump SERCA2. MANF loss causes pathological SERCA2 accumulation, MAM hyperassembly, and disrupted ER‐to‐mitochondria Ca2+ transfer, leading to mitochondrial failure, oxidative ...
Xin Liu   +8 more
wiley   +1 more source

Clinical science effects of different mydriatics on retinal and choroidal parameters in healthy adults observed by widefield swept-source optical coherence tomography

open access: yesBMJ Open Ophthalmology
Purpose To assess retinal and choroidal changes following rapid mydriasis in healthy adults.Methods Seventy-one volunteers (71 right eyes) participated in a prospective randomised controlled trial.
Jianmin Shang   +7 more
doaj   +1 more source

Randomized Clinical Trial on the Efficacy and Side Effects of Tropicamide and Phenylephrine in Mydriasis for Ophthalmoscopy

open access: yesJournal of Optometry, 2010
Purpose: To compare the efficacy and side effects of two combinations of tropicamide and phenylephrine as mydriatics for ophthalmoscopy. Methods: In this prospective randomized controlled trial, 51 Chinese outpatients were randomized to receive topical ...
Philip T.H. Lam   +4 more
doaj   +1 more source

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