Results 191 to 200 of about 32,249 (223)
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Journal of Neurochemistry, 2018
AbstractAstrocytes are glial cells that help maintain brain homeostasis and become reactive in neurodegenerative processes releasing both harmful and beneficial factors. We have demonstrated that brain‐derived neurotrophic factor (BDNF) expression is induced by melanocortins in astrocytes but BDNF actions in astrocytes are largely unknown.
Julieta Saba +6 more
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AbstractAstrocytes are glial cells that help maintain brain homeostasis and become reactive in neurodegenerative processes releasing both harmful and beneficial factors. We have demonstrated that brain‐derived neurotrophic factor (BDNF) expression is induced by melanocortins in astrocytes but BDNF actions in astrocytes are largely unknown.
Julieta Saba +6 more
openaire +3 more sources
Journal of Neuro-Oncology, 2011
All-trans retinoic acid (ATRA) plays crucial roles in cell survival and differentiation of neuroblastoma cells. In the present study, we investigated the effects of geranylgeranoic acid (GGA), an acyclic retinoid, on differentiation and tropomyosin-related kinase receptor B (TrkB) gene expression in SH-SY5Y human neuroblastoma cells in comparison with ...
Chiharu, Sakane, Yoshihiro, Shidoji
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All-trans retinoic acid (ATRA) plays crucial roles in cell survival and differentiation of neuroblastoma cells. In the present study, we investigated the effects of geranylgeranoic acid (GGA), an acyclic retinoid, on differentiation and tropomyosin-related kinase receptor B (TrkB) gene expression in SH-SY5Y human neuroblastoma cells in comparison with ...
Chiharu, Sakane, Yoshihiro, Shidoji
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Pharmacology & Therapeutics, 2008
The focus of this review is to critically examine and review the literature on the role of brain-derived neurotrophic factor (BDNF) and its primary receptor, tropomyosin-related kinase B (TrkB), in the actions of pharmacologically diverse antidepressant treatments for depression.
Megan E, Kozisek +2 more
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The focus of this review is to critically examine and review the literature on the role of brain-derived neurotrophic factor (BDNF) and its primary receptor, tropomyosin-related kinase B (TrkB), in the actions of pharmacologically diverse antidepressant treatments for depression.
Megan E, Kozisek +2 more
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Neuroscience Letters, 2020
Tropomyosin-related kinase B receptor (TrkB) is one of the new candidate receptors for drugs targeting psychiatric and neurodegenerative disorders. Recently, 7,8-dihydroxyflavone (7,8-DHF) has been identified as a selective TrkB agonist that crosses the blood-brain barrier after oral or intraperitoneal administration, and it enhances cued fear ...
Suguru Tohyama +2 more
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Tropomyosin-related kinase B receptor (TrkB) is one of the new candidate receptors for drugs targeting psychiatric and neurodegenerative disorders. Recently, 7,8-dihydroxyflavone (7,8-DHF) has been identified as a selective TrkB agonist that crosses the blood-brain barrier after oral or intraperitoneal administration, and it enhances cued fear ...
Suguru Tohyama +2 more
openaire +2 more sources
Cancer Research, 2014
Abstract Background: Tropomyosin-related receptor kinase B (TrkB) promotes proliferation and invasion related to poor prognoses of various malignancies. TrkB is also involved in resistance to anoikis (a form of detachment-induced apoptosis) and epithelial-to-mesenchymal transition (EMT).
Koji Tanaka +13 more
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Abstract Background: Tropomyosin-related receptor kinase B (TrkB) promotes proliferation and invasion related to poor prognoses of various malignancies. TrkB is also involved in resistance to anoikis (a form of detachment-induced apoptosis) and epithelial-to-mesenchymal transition (EMT).
Koji Tanaka +13 more
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The Journal of Pain, 2019
A rat model of neuropathic pain at 6 weeks after spinal nerve ligation (SNL6w) exhibits both mechanical hypersensitivity and impaired noxious stimuli-induced analgesia (NSIA). Repeated treatment with antidepressants can produce antihypersensitivity and restore NSIA. To examine the involvement of a brain-derived neurotrophic factor-mediated mechanism, a
Takashi, Suto +3 more
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A rat model of neuropathic pain at 6 weeks after spinal nerve ligation (SNL6w) exhibits both mechanical hypersensitivity and impaired noxious stimuli-induced analgesia (NSIA). Repeated treatment with antidepressants can produce antihypersensitivity and restore NSIA. To examine the involvement of a brain-derived neurotrophic factor-mediated mechanism, a
Takashi, Suto +3 more
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Tropomyosin-related kinase B receptor polymorphisms and isoforms expression in suicide victims
Psychiatry Research, 2014Federica Zarrilli +9 more
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Journal of the Neurological Sciences, 2021
Tamara Filimonova, Yulia Karakulova
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Tamara Filimonova, Yulia Karakulova
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