Results 61 to 70 of about 113,140 (309)

Illuminating the Intracellular World: Breakthroughs in Nanoscale Optoelectronics

Advanced Electronic Materials, EarlyView.
This perspective explores optoelectronic biointerfaces spanning macroscale flexible devices to nanoscale intracellular systems, emphasizing their integration across dimensions. It examines capacitive, Faradaic, and photothermal mechanisms that enable light‐driven control of cellular activity and highlights key material and design challenges in ...
Tania Assaf, Menahem Y. Rotenberg
wiley   +1 more source

Clinical Utility of Cardiac Troponin I and Cardiac Troponin T Measurements

Acta Medica, 1997
The measurement of CK-MB remains the test of choice for confirmation or exclusion of AMI and probably will remain the test of choice for routine diagnosis in the near future.
Michaela Adamcová, Zdeněk Kokštein, Jaroslava Vávrová   +2 more
doaj   +1 more source

Targeted Anti‐IL‐1 Immunomodulatory Therapy in Pediatric Onset PPP1R13L‐Related Arrhythmogenic Cardiomyopathy

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Autosomal recessive loss‐of‐function variants in PPP1R13L cause an ultra‐rare cardiocutaneous syndrome characterized by rapidly progressive arrhythmogenic cardiomyopathy (ACM). PPP1R13L encodes iASPP, which has two potentially overlapping mechanisms driving ACM as both a regulator of NFκB‐mediated inflammation and a binding partner within the ...
Aaron Renberg, Savannah Coppersmith, Owen Merritt, Amer Heider, Adam Helms, Thomas Michniacki, Jack Luxford, Sarah Josephi‐Taylor, Philip Roberts, Joshua Meisner   +9 more
wiley   +1 more source

Cardiac Troponin I is released following high intensity short-duration exercise in healthy humans

, 2010
It has been previously shown that cardiac troponin (cTn) is released in response to prolonged endurance exercise. The influence of short-duration high-intensity exercise upon the release of cTn is not known.
Ross, P., Low, D., Gaze, D.C., George, K., Shave, R.   +4 more
core   +1 more source

Interleukin‐2 Deprived State of Regulatory T cells and Their Recovery by Low‐Dose Interleukin‐2 in Patients With Inflammatory Myopathies

Arthritis &Rheumatology, EarlyView.
Objective Regeneration and expansion of Treg by low‐dose interleukin‐2 (IL‐2) therapy is considered a potential treatment strategy for a wide range of autoimmune diseases. To provide a pathophysiologically‐based rationale for low‐dose IL‐2 therapy, we investigated whether reversible defects in the Treg–IL‐2 axis emerge in inflammatory myopathies ...
Justus Ohmes, Luisa R. Monne, Sara Comdühr, Fynn Gerlach, Hanna Grasshoff, Alexander Dübbers, Antje Müller, Alexander Scheffold, Gabriela Riemekasten, Reza Akbarzadeh, Jens Y. Humrich   +10 more
wiley   +1 more source

Cardiac troponin i in acute pericarditis

Journal of the American College of Cardiology, 2003
This study was designed to investigate the prognostic value of cardiac troponin I (cTnI) in viral or idiopathic pericarditis.Idiopathic acute pericarditis has been recently reported as a possible cause of nonischemic release of cTnI. The prognostic value of this observation remains unknown.We enrolled 118 consecutive cases (age 49.2 +/- 18.4 years; 61 ...
Imazio M, Demichelis B, Cecchi E, Belli R, Ghisio A, Bobbio M, Trinchero R   +6 more
openaire   +4 more sources

First‐in‐human, phase I, randomized, safety, pharmacokinetic, food‐effect and pharmacodynamic study of a tyrosine kinase 2/Janus kinase 1 inhibitor, SDC‐1801

British Journal of Clinical Pharmacology, EarlyView.
Aim The purpose of this study is to evaluate safety, tolerability, pharmacokinetics (PK), food‐effect (FE) and pharmacodynamics (PD) of an oral tyrosine kinase‐2 (TYK2)/Janus kinase‐1 (JAK1) inhibitor, SDC‐1801, in healthy adult participants. Methods This first‐in‐human study randomized 95 male and female participants.
Chris Brearley, Sam Francis, John Reader, Judi Proctor   +3 more
wiley   +1 more source

Troponin I expression.

, 2016
Immunoblot and densitometry of phosphorylated troponin I (P-TnI) and total troponin I (TnI) in 8-week-old wildtype (WT) and Tnnt2R141W/+ hearts. n = 3 for wildtype and n = 3 for Tnnt2R141W/+.
Michele L. Pruce (3390971), Sanjay K. Banerjee (377266), Ravi K. Sharma (1975222), Bethann E. Gabris (3390968), Sanjeev G. Shroff (377277), Guy Salama (1340829), Mohun Ramratnam (3390974), Stephen H. Smith (377269), Lindsey M. Gifford (3390962), David Wen Rui Wang (3390965), Xueyin N. Huang (377268), Ferhaan Ahmad (173134), Samir Saba (377270)   +12 more
core   +1 more source

Machine Learning Models of Phase Contrast Images Predict Efficiency of Human Pluripotent Stem Cell Differentiation to Cardiomyocytes

Biotechnology and Bioengineering, EarlyView.
Human pluripotent stem cells were differentiated to cTnT+ cardiomyocytes and imaged throughout the process using phase contrast. We predicted differentiation efficiency (cTnT+ area) from phase contrast and compared model performance with a live‐cell cTnT‐GFP reporter.
Austin K. Feeney, Yaniv Ovadia, Aaron D. Simmons, Christian Elabd, Claire J. Peplinski, Frank Li, Sean P. Palecek   +6 more
wiley   +1 more source

Assessment of cardiac troponin I in patients with pulmonary emboli and its relationship with right ventricular dysfunction

Journal of Mazandaran University of Medical Sciences, 2009
(Received 16 December, 2008; Accepted 27 May, 2009)AbstractBackground and purpose: Right ventricular dysfunction is common in major pulmonary embolisms. The purpose of this study was to evaluate the prevalence and diagnostic utility of cardiac troponin I
Sasan Tavana, Yunes Panahi, Nasrollah Saed Moucheshi, Fatemeh Beiraghdar, Ebrahim Naderi3Department of Internal Medicine, Faculty of Medicine, Hamedan University of Medical Sciences, Hamedan, Iran, Shahram Ala, Rouhollah Habibey   +6 more
doaj