Results 101 to 110 of about 31,429 (242)

AI‐Driven Synthesis in Medicinal Chemistry: Integrating Large Language Models, Robotic Automation, and Sustainability Metrics to Accelerate Drug Discovery

Medicinal Research Reviews, EarlyView.
ABSTRACT Artificial intelligence (AI) is transforming synthetic chemistry from task‐specific predictors into integrated platforms that unify retrosynthesis, reaction optimization, and closed‐loop robotic automation. This review highlights how AI‐assisted planning and robotic execution shorten cycle times, reduce step counts, and improve route ...
Amit Gangwal, Antonio Lavecchia
wiley   +1 more source

IgG Subclass (IgG1‐4) and IgA Autoantibody Profiles Against Muscle‐Specific Kinase in a Greek Cohort

Muscle &Nerve, EarlyView.
ABSTRACT Introduction/Aims Muscle‐specific kinase myasthenia gravis (MuSK‐MG) is an autoimmune neuromuscular disorder predominantly mediated by IgG4 autoantibodies disrupting MuSK signaling. The contribution of other isotypes remains incompletely defined. We characterized the serological profile of a Greek cohort of MuSK‐MG patients.
Sofia‐Natsοuko Gkotzamani, Maria Pechlivanidou, Francisca Faber, Cansu Elmas, Vasiliki Zouvelou, Elisabeth Chroni, Dimitrios Tzanetakos, Maria Kourouvani, Marlene Wolfsgruber, Ioannis Zaganas, Dimitra Kolovou, Michael Rentzos, Ariadne Daponte, Maria Chondrogiorgi, Spyridon Konitsiotis, Georgios Nicolaou, Stavroula Salakou, Sotirios Giannopoulos, Konstandinos Lazaridis, Georgios Tsivgoulis, Socrates Tzartos, Inga Koneczny, John S. Tzartos   +22 more
wiley   +1 more source

Incidence of unplanned gastrostomy tube replacements and associated complications in people with motor neurone disease and other conditions: A retrospective audit of an Australian dietitian‐led clinic

Nutrition in Clinical Practice, EarlyView.
Abstract Background Gastrostomy tube placement is a common intervention for long‐term nutrition in people with dysphagia. Minimising complications such as tube dislodgement is integral in gastrostomy management, as unplanned replacements may require urgent care to prevent stoma closure.
Emily Farrugia, Shanelle Bailey, Adam I. Semciw, Mani Suleiman, Mark Tacey, Caroline J. Tuck, Liam M. Hannan   +6 more
wiley   +1 more source

“REACH’’ for troubleshooting peripheral defocus myopia control spectacles

Frontiers in Ophthalmology
Sujit Shah, Gautam Motwani, Pavan K. Verkicharla   +2 more
doaj   +1 more source

Barriers to Care for Obstructive Sleep Apnea: Primary Care Perspectives at a Safety Net Hospital. [PDF]

Laryngoscope Investig Otolaryngol
Florentine M, Gulati A, Hernandez R, Chang JL, Durr ML.   +4 more
europepmc   +1 more source

Practical considerations for pathologists when selecting digital pathology systems: an ESDIP guide

The Journal of Pathology, EarlyView.
Abstract The implementation of digital pathology (DP) has been reported across academic, public, and private laboratory settings, providing valuable insights into workflow transformation. However, comparatively little guidance exists on how DP systems should be evaluated prior to acquisition and deployment.
Diana Montezuma, Vincenzo L'Imperio, David Ameisen, Rita Carvalho, Peter Boor, Sara P Oliveira, Nadieh Khalili, Inti Zlobec, Norman Zerbe, Jordi Temprana‐Salvador   +9 more
wiley   +1 more source

Adverse events and device malfunctions in robotic thyroidectomy: a decade-long analysis of the MAUDE database. [PDF]

J Robot Surg
Zhan L, Deng X, Lin Q, Song B, Lin Z, Pan L, Wu Z, Wang Z, Ding Z, Wu B, Guo B, Fan Y.   +11 more
europepmc   +1 more source

Translating Machine Learning Into Manufacturing Expertise—Actionable Interpretability and Stability for Precision Injection Molding

Polymer Engineering &Science, EarlyView.
This research aims to enhance confidence in using AI/ML models and address unpredicted defects occurred during injection molding (IM) through guided machine fine‐tuning. Integrated stability analysis and parallel coordinate visualization coupled with perturbation analysis are presented to augment domain‐specific XAI applications in the IM industry ...
Chung‐Yin Lin, Jinsu Gim, Andrea Pieressa, Demitri Shotwell, Kris Sankaran, Giovanni Lucchetta, Lih‐Sheng Turng   +6 more
wiley   +1 more source

Troubleshooting of plastic stent impaction in the working channel during endoscopic ultrasound-guided hepaticogastrostomy. [PDF]

Endoscopy
Murabayashi T, Okuda H, Sugimoto S.
europepmc   +1 more source

Optimizing Na and Rb Incorporation Along With Bandgap Grading for High Efficiency Ultra‐Thin CIGSe Solar Cells

Progress in Photovoltaics: Research and Applications, EarlyView.
In this work, Na and Rb are incorporated into ultra‐thin Cu(In,Ga)Se2 (< 500 nm). By systematically varying the Rb content and combining predeposited Na with postdeposited Rb, we identify the optimal configuration, achieving solar cell efficiencies of 11.72% on Mo and 10.48% on ITO. Through electrical and compositional measurements, a mechanistic model
Christoph Rath, Tristan Köhler, Martina Schmid   +2 more
wiley   +1 more source