Results 61 to 70 of about 7,256,584 (328)
Molecular bases of circadian magnesium rhythms across eukaryotes
FEBS Letters, EarlyView.Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Crowdsourcing malaria parasite quantification: an online game for analyzing images of infected thick blood smears [PDF]
, 2012 Background: There are 600,000 new malaria cases daily worldwide. The gold standard for estimating the parasite burden and the corresponding severity of the disease consists in manually counting the number of parasites in blood smears through a microscope,
Abt, C +10 more
core +2 more sources
PICALM::MLLT10 translocated leukemia
FEBS Letters, EarlyView.This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
Journal of Pure and Applied MicrobiologyCoagulase-negative staphylococci (CoNS) are primary skin commensals that have long been considered contaminants even when grown in blood cultures. This group of organisms has been recently recognized as a potential causative pathogen of septicemia.
S. Anitha +7 more
doaj +1 more source
TV Series, 2012 Alan Ball, the critically-acclaimed screenwriter of American Beauty, launched his first series project in 2001 with Six Feet Under. His somber but humorous account of the dysfunctional Fisher family’s life and death in suburban Los Angeles held a ...
Anne-Marie Paquet-Deyris
doaj +1 more source
Emergence of the verification phase procedure for confirming 'true' VO2max [PDF]
, 2009 Traditional VO2max criteria are typically based on attainment of a VO2 plateau, and threshold values for the respiratory exchange ratio, heart rate and blood lactate concentration.
Astrand, Thoden, Thoden
core +1 more source
Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology
Molecular Oncology, EarlyView.Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts +8 more
wiley +1 more source
TV Series, 2014 In seasons 5 and 6 of True Blood, the appearance of Lilith, a character borrowed from the Jewish tradition and presented in the show as the original vampire, permits us to analyze the relationship of this fantasy show with religion.
Maureen Attali
doaj +1 more source
Scientific Reports, 2021 We aimed to determine whether puncture sites for blood sampling and topical disinfectants are associated with rates of contaminated blood cultures in the emergency department (ED) of a single institution.
Koshi Ota +9 more
doaj +1 more source