Results 91 to 100 of about 106,175 (350)

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

A comparative evaluation of intraoral and extraoral digital impressions: An in vivo study

The Journal of Indian Prosthodontic Society, 2018
Aim: The accuracy of a dental impression is determined by two factors: “trueness” and “precision.” The scanners used in dentistry are relatively new in market, and very few studies have compared the “precision” and “trueness” of intraoral scanner with ...
Gursharan Kaur Sason, Gaurang Mistry, Rubina Tabassum, Omkar Shetty   +3 more
doaj   +1 more source

Effects of Trueness and Surface Microhardness on the Fitness of Ceramic Crowns

Applied Sciences, 2020
This study aims to evaluate the fitness, surface microhardness, and trueness of crowns fabricated from three types of dental ceramic blocks (HASS Rosetta, IPS e.max CAD, and VITA Suprinity) and analyze the correlations between them.
Kunhee Lee, Keunbada Son, Kyu-bok Lee
doaj   +1 more source

Report on the Verification of the Performance of MON 15985 and MON 1445 Event-specific Methods on the Cotton Event MON 15985 x MON 1445 Using Real-Time PCR [PDF]

, 2010
The JRC as Community Reference Laboratory for GM Food and Feed (CRL-GMFF), established by Regulation (EC) No 1829/2003, has carried out an in-house verification study to assess the performance of two quantitative event-specific methods on the cotton ...
LUQUE PEREZ Encarnacion, MAZZARA Marco, MUNARO Barbara, SAVINI Cristian, VAN DEN EEDE Guy   +4 more
core   +1 more source

Insights into a long life without cancer: The case of the bowhead whale

Molecular Oncology, Volume 20, Issue 6, Page 1388-1391, June 2026.
Long‐lived, large‐bodied organisms have evolved powerful anticancer mechanisms that preserve cellular and tissue integrity across extended lifespans. A recent study by Firsanov et al. shows that greater genome stability is a key factor underlying the remarkable longevity and cancer resistance of one such species, the bowhead whale.
Inés Paniagua, Johanna A. Joyce
wiley   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source

Palatal Vault Depth Affects the Accuracy of the Intaglio Surface of Complete Maxillary Denture Bases Manufactured Through Additive Manufacturing

Oral
Background/Objectives: The purpose of this in vitro study is to evaluate the effect varying palatal vault depths have on the accuracy of complete maxillary denture bases fabricated using additive manufacturing technology.
Ben J. Smith, Louis George, Duman Davari, Jeremy Collins, Jordan Orth, Mahmoud M. Bakr, Santosh Kumar Tadakamadla, Andrew B. Cameron   +7 more
doaj   +1 more source

Verification of the Performance of Bt11, MIR604 and GA21 Maize Event-specific Methods on the Maize Event Bt11 x MIR604 x GA21 Using Real-time PCR. Validation Report and Protocols [PDF]

, 2010
The European Union Reference Laboratory for GM Food and Feed (EURL-GMFF), established by Regulation (EC) No 1829/2003, has carried out a verification study to assess the performance of three quantitative event-specific methods on the maize event Bt11 x ...
CHARLES DELOBEL Chrystele, MAZZARA Marco, MUNARO Barbara, VAN DEN EEDE Guy   +3 more
core   +1 more source

Evaluation of 3D Facial Scanners: Trueness & Precision

Aim This paper evaluates the precision and trueness of facial scanners (FSs) by analyzing facial scans from ten 3D scanners, consisting of five professional devices and five mobile applications. Material and Methods A 3D facial model with human-like dimensions, shape, and proportions, featuring reference points, was used to standardize measurements.
Luca Giannetti, Omar Shanableh, Francesco Mintrone   +2 more
openaire   +1 more source

Molecular cancer prevention: Intercepting disease

Molecular Oncology, Volume 20, Issue 6, Page 1392-1397, June 2026.
Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco, Tej Pandya, Charles Swanton   +2 more
wiley   +1 more source