Results 91 to 100 of about 330,573 (298)
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Сравнительная политика, 2018 The article is focused on the analysis of the evident and hidden reasons of the deep political crisis between USA and Germany. The role of the Donald Trump’s personality is considered as an important factor infl uencing the dialogue between Berlin and ...
E. V. Pimenova
doaj +1 more source
Obama\u27s Legacy for Education Policy
, 2017 Last night Barack Obama delivered his farewell address to a raucous crowd in Chicago. This morning, Donald Trump delivered his first press conference as president-elect in front of a surprisingly raucous crowd at Trump Tower in New York.
Powell, Dave
core
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Trump’s New Trade Policy: Risks for North American Food and Farms [PDF]
, 2018 In his presidential campaign, Trump promised to build a “great, great wall”, and he promised to renegotiate the terms of the North American Free Trade Agreement (NAFTA), leaving open the possibility of pulling out entirely.
Hansen Kuhn, Karen
core +2 more sources
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
THE 45TH PRESIDENT OF THE UNITED STATES: THE MECHANISM OF VICTORY DONALD TRUMP ON ELECTION
Современная наука и инновации, 2022 Presidential Election of 2016 has become an exceptional event in the contemporary history of the US. Election of the extravagant billionaire Donald Trump has proved all forecasts wrong and became a total surprise for many.
Maxim Aleksandrovich Suchkov
doaj