Results 91 to 100 of about 14,023,448 (242)
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Freinet en España (1926-1939) - Freinet in Spain (1926-1939)
História da Educação, 2012 Freinet na Espanha (1926-1939)ResumoOs postulados sobre educação de Celestín Freinet, em seu empenho de dotar a Cooperativa de Ensino Laico - CEL - de um caráter internacional, transcendem as fronteiras francesas.
José Luis Hernández Huerta +1 more
doaj
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Vague Convergence in the Truncated Moment Problem
, 1991 A result by Mead and Papanicolaou is proved without the assumption of absolute continuity and without the use of maximum entropy; if $\mu_n$ is any probability distribution that solves the truncated moment problem, viz.
SEMPI, Carlo
core
Mach Disk Shape in Truncated Ideal Contour Nozzles [PDF]
, 2007 DLR Lampoldshausen carried out cold flow tests to study the flow field in a truncated ideal contour nozzle at low nozzle pressure ratios. A convex shaped Mach disk was found for nozzle pressure ratios less than 10 and a slight concave one for nozzle ...
Stark, Ralf, Wagner, Bernd
core
Szego polynomials and the truncated trigonometric moment problem
, 2006 We show how Szego polynomials can be used in the theory of truncated trigonometric moment ...
core +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
A truncated indefinite Stieltjes moment problem [PDF]
, 2016 A truncated indefinite Stieltjes moment problem in the class Nkκ of generalized Stieltjes functions is studied. The set of solutions of Stieltjes moment problem is described by Schur step-by-step algorithm, which is based on the expansion of the ...
Kovalyov, I.M.
core +1 more source