Results 61 to 70 of about 14,023,448 (242)

Evolutionary patterns of structural disorder and post-translational modifications in the 18.5 kDa myelin basic protein

Studia Universitatis Babeș-Bolyai. Biologia
Myelin basic protein (MBP, 18.5 kDa isoform) is a key structural component of the myelin sheath, where it drives multilayer compaction through electrostatic interactions and dynamic conformational transitions.
Ilka Koszorus, Ferencz Kósa
doaj   +1 more source

Experience With Performing Rheocarna Therapy via the Single‐Needle Method for Treatment of Chronic Limb‐Threatening Ischemia

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This study investigated the safety and efficacy of single‐needle Rheocarna therapy for chronic limb‐threatening ischemia (CLTI) with wounds. Methods Six patients with CLTI involving ulcers unresponsive to revascularization underwent single‐needle Rheocarna treatment.
Yasutaka Yamauchi, Rie Tanaka, Reona Kawahira, Shingo Nabeta, Kouhei Naoi, Kazuhito Kitajima, Akira Wada, Tomonari Takagi, Norihiko Ohura, Akira Miyamoto   +9 more
wiley   +1 more source

DTDA: An R Package to Analyze Randomly Truncated Data [PDF]

In this paper, the R package DTDA for analyzing truncated data is described. This package contains tools for performing three different but related algorithms to compute the nonparametric maximum likelihood estimator of the survival function in the ...
Rosa M. Crujeiras, Jacobo de Uña-Álvarez, Carla Moreira   +2 more
core  

Effectiveness of Resistance Intradialytic Exercise Compared to Aerobic Intradialytic Exercise for Patients With Chronic Kidney Disease: A Randomized Controlled Clinical Trial

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Patients with chronic kidney disease undergoing hemodialysis commonly experience reduced physical function, fatigue, poor sleep quality, and impaired health‐related quality of life. Intradialytic exercise has been proposed as a non‐pharmacological strategy to improve these outcomes.
Klebson da Silva Almeida, Gisela Cristiane Miyamoto, Daniel da Costa Torres, Ian Setubal Reis Chaves, Jonas do Carmo Paschoalin, Braúlio Lima Nascimento, Luciana Dias Chiavegato   +6 more
wiley   +1 more source

Protein trans-splicing: optimization of intein-mediated GFP assembly as a model for the development of gene therapy

Frontiers in Bioengineering and Biotechnology
Adeno-associated virus (AAV)-based gene therapy has become one of the key directions of modern translational medicine geared towards treatment of hereditary disorders by means of gene replacement.
Andrew Brovin, Ekaterina Minskaia, Matvei Sabantsev, Sergey Chuvpilo, Alexander Karabelsky   +4 more
doaj   +1 more source

TRUNCATED REGRESSION IN EMPIRICAL ESTIMATION [PDF]

In this paper we illustrate the use of alternative truncated regression estimators for the general linear model. These include variations of maximum likelihood, Bayesian, and maximum entropy estimators in which the error distributions are doubly ...
Mittelhammer, Ronald C., Marsh, Thomas L.   +1 more
core  

Serum Myonectin Levels Are Positively Associated With Physical Function and Lower Frailty‐Related Limitation in Maintenance Hemodialysis Patients: A Cross‐Sectional Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Maintenance hemodialysis (MHD) patients frequently suffer from frailty, characterized by reduced physical function and poor prognosis. Myokines, such as myonectin, secreted by muscle, are emerging regulators of systemic health. This study investigated the relationship between serum myonectin, adipokines (adiponectin, omentin), and ...
Kenichi Kono, Yoshifumi Moriyama, Koji Ohashi, Naoya Otaka, Minako Tatsumi, Toyoaki Murohara, Noriyuki Ouchi, Satoru Oshima   +7 more
wiley   +1 more source

OPTIMIZATION AND APPROXIMATION OF NC POLYNOMIALS WITH SUMS OF SQUARES

Croatian Operational Research Review, 2010
In this paper we study eigenvalue optimization of non-commutative polynomials. That is, we compute the smallest or biggest eigenvalue a non-commutative polynomial can attain. Our algorithm is based on sums of hermittian squares.
Kristijan Cafuta, Igor Klep
doaj  

An improved composite ship magnetic field model with ellipsoid and magnetic dipole arrays

Scientific Reports
In order to simultaneously maintain the ship magnetic field modeling accuracy, reduce the number of coefficient matrix conditions and the model computational complexity, an improved composite model is designed by introducing the magnetic dipole array ...
Binjie Lu, Xiaobing Zhang
doaj   +1 more source

Modelling Hydrological Droughts in Canadian Rivers Based on Markov Chains Using the Standardized Hydrological Index as a Platform

Hydrology
The standardized hydrological index (SHI) is the standardized but not normalized (normal probability variate) value of the streamflow used to characterize a hydrological drought, akin to the standardized precipitation index (SPI, which is both ...
Tribeni C. Sharma, Umed S. Panu
doaj   +1 more source