Results 91 to 100 of about 91,565 (275)

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

open access: yesAging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu   +8 more
wiley   +1 more source

Enhancing artificial neural network learning efficiency through Singular value decomposition for solving partial differential equations

open access: yesResults in Applied Mathematics
Partial differential equations (PDEs) hold significant potential for modelling natural phenomena. It is essential to look at a practical way to solve the PDEs.
Alfi Bella Kurniati   +3 more
doaj   +1 more source

Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky   +8 more
wiley   +1 more source

RF Tomography in Free Space: Experimental Validation of the Forward Model and an Inversion Algorithm Based on the Algebraic Reconstruction Technique

open access: yesInternational Journal of Antennas and Propagation, 2013
Radio-frequency tomography was originally proposed to image underground cavities. Its flexible forward model can be used in free-space by choosing an appropriate dyadic Green's function and can be translated in the microwave domain. Experimental data are
V. Picco   +4 more
doaj   +1 more source

Multidimensional Profiling of MRI‐Negative Temporal Lobe Epilepsy Uncovers Distinct Phenotypes

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Although hippocampal sclerosis (TLE‐HS) represents the most frequent cause of temporal lobe epilepsy (TLE), up to 30% of patients show no lesion on visual MRI inspection (TLE‐MRIneg). These cases pose diagnostic and therapeutic challenges and are underrepresented in surgical series.
Alice Ballerini   +28 more
wiley   +1 more source

On the truncated multilinear singular value decomposition

open access: yes, 2011
In this report, we investigate the truncated multilinear singular value decomposition (MLSVD), as presented in [L. De Lathauwer, B. De Moor and J. Vandewalle, a multilinear singular value decomposition, 2000]. The T-MLSVD comprises a Tucker decomposition [L.R.
Vannieuwenhoven, Nick   +2 more
openaire   +1 more source

Polynomial basis conversion made stable by truncated singular value decomposition

open access: yesApplied Mathematical Modelling, 1997
The aim of this paper is to provide a numerically stable method for the transformation between the power and the Bernstein basis resp. the Bernstein and the B-spline basis. Although this transformation process is defined by a system of linear equations, the direct use of this linear system is sometimes not recommended, since it may be ill conditioned ...
openaire   +1 more source

Relationship Between Neurologic Symptoms and Signs and FMR1 Genotype in Premutation Carriers

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Fragile X‐associated Tremor/Ataxia Syndrome (FXTAS) is the most severe late‐onset condition caused by a premutation in the FMR1 gene, characterized by expanded CGG triplet repeats of 55–200. Clinical presentations of FXTAS, including gait ataxia, kinetic tremor, cognitive decline, and rare Parkinsonism, are linked to ...
Flora Tassone   +8 more
wiley   +1 more source

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