Results 171 to 180 of about 129,248 (267)

Hierarchical Truncations for Many-Body Expansion Potentials. [PDF]

open access: yesJ Chem Theory Comput
Westheimer BM   +3 more
europepmc   +1 more source

KRT14 Drives Basal Muscle‐Invasive Bladder Cancer Progression and Lung Metastasis by Directly Binding to and Stabilizing IGF2BP1

open access: yesAdvanced Science, EarlyView.
We identified a Krt14+ Igf2bp1+ bladder cancer population linked to EMT. Mechanistically, KRT14 stabilizes and transports IGF2BP1 to invasive protrusions, initiating a positive feedback loop that drives metastasis and poor outcomes. ABSTRACT Basal‐type muscle‐invasive bladder cancer (BMIBC) is characterized by aggressive metastasis and poor prognosis ...
Shirui Huang   +19 more
wiley   +1 more source

CCT2 Promotes Prostate Cancer Progression Through EIF3F‐Dependent Stabilization of FASN

open access: yesAdvanced Science, EarlyView.
ABSTRACT Prostate cancer (PCa) is increasingly recognized to be driven by dysregulated lipid metabolism. Although fatty acid synthase (FASN) is highly expressed in PCa, the mechanisms governing FASN protein stability and its functional integration into oncogenic lipid metabolism remain poorly defined.
Shun Xu   +13 more
wiley   +1 more source

Femtosecond‐Laser‐Induced Physical Unclonable Random Maze Structure for Storage‐Free Encryption

open access: yesAdvanced Science, EarlyView.
Femtosecond‐laser‐induced gold random maze structures serve as multimodal physical unclonable functions for storage‐free encryption. Their stochastic optical, electrical, and Raman responses are generated by plasmon‐assisted Marangoni formation and converted into AES‐compatible keys without permanent secret‐key storage, offering a portable route toward
Shiru Jiang   +6 more
wiley   +1 more source

Weighted (p,q)-equations with gradient dependent reaction

open access: yesElectronic Journal of Differential Equations
Zhao Jing   +2 more
doaj  

RaptScore: a large language model-based algorithm for versatile aptamer evaluation. [PDF]

open access: yesNucleic Acids Res
Kimura-Yamazaki A   +4 more
europepmc   +1 more source

Discriminator‐Guided Inverse Folding for Multi‐Property Protein Design

open access: yesAdvanced Science, EarlyView.
Discriminator‐Guided Inverse Folding (DGIF) integrates multiple property predictors trained from single‐property datasets to guide protein sequence generation from a backbone structure. DGIF enables simultaneous improvement of thermostability and solubility without requiring multi‐property annotated datasets and generates designs that move toward the ...
Yuchuan Zheng   +7 more
wiley   +1 more source

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