Weighted (p,q)-equations with gradient dependent reaction
Zhao Jing +2 more
doaj
Generation and epitope mapping of monoclonal antibodies targeting the avian reovirus S1133 σC protein. [PDF]
Deng H +5 more
europepmc +1 more source
Engineering a 660 nm‐Responsive Optogenetic Inducer of Pyroptosis for Precision Cancer Therapy
This study reports a bioorthogonal pyroptosis inducer, PyroRACS. By using a red‐light‐responsive Cre‐On genetic switch to control the expression of highly cytotoxic GSDMDNT, PyroRACS enables the artificial induction of pyroptosis with precise spatiotemporal control.
Mengkai Zhang +5 more
wiley +1 more source
CT-less attenuation correction in a patient with BMI of 77. [PDF]
Bartel T +5 more
europepmc +1 more source
RGS16 competitively interferes with the YTHDF3–PAN3 complex to prevent CXCL1 mRNA decay during hepatic ischemia‐reperfusion injury. Stabilized CXCL1 strengthens hepatocyte injury, neutrophil recruitment, and NET‐associated inflammation, uncovering how stress‐induced RGS16 converts post‐transcriptional regulation into immune‐mediated liver damage ...
Xinglong Li +16 more
wiley +1 more source
Kolmogorov-Smirnov and Cramér-von Mises tests for the k-sample problem with left-truncated and right-censored data. [PDF]
Lago A +2 more
europepmc +1 more source
Deltacoronavirus Modulates circRNA cGLIS3 Metabolism to Evade Host Antiviral Response
This study reveals that both deltacoronavirus nucleocapsid protein and host RNA binding protein IGF2BP2 promote circular RNA GLIS3 (cGLIS3) biogenesis by binding to GLIS3 pre‐mRNA. The m6A modification‐mediated cGLIS3‐IGF2BP2 interaction weakens RNase L‐mediated degradation of cGLIS3 while facilitates a ubiquitin‐dependent degradation of IGF2BP2, thus ...
Liuyang Du +10 more
wiley +1 more source
The evolutionarily conserved C-terminal tail of the Dib1 protein is required for spliceosome efficacy and Dib1 protein stability. [PDF]
Dye B +5 more
europepmc +1 more source
A schematic model summarizing GNA15's mechanism in mediating macrophage M2 polarization and Gemcitabine resistance. ABSTRACT The complexity of pancreatic ductal adenocarcinoma (PDAC) progression, coupled with the lack of effective immunotherapy, underscores the imperative to deepen our understanding of its mechanisms and identify suitable immune ...
Weihui Guo +8 more
wiley +1 more source
Structural analysis of recombinant AAV vector genomes at single-molecule resolution. [PDF]
Rouleau D +6 more
europepmc +1 more source

