Results 51 to 60 of about 1,668,256 (289)

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

The Trusted Computing Exemplar Project [PDF]

open access: yes, 2004
We describe the Trusted Computing Exemplar project, which is producing an openly distributed worked example of how high assurance trusted computing components can be built.
George W. Dinolt Member   +9 more
core   +2 more sources

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

open access: yesFEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill   +6 more
wiley   +1 more source

Memway: In-Memory Waylaying Acceleration for Practical Rowhammer Attacks Against Binaries

open access: yesTsinghua Science and Technology, 2019
The Rowhammer bug is a novel micro-architectural security threat, enabling powerful privilege-escalation attacks on various mainstream platforms.
Lai Xu   +3 more
doaj   +1 more source

Privacy Inference Attack Against Users in Online Social Networks: A Literature Review

open access: yesIEEE Access, 2021
With the rapid development of social networks, users pay more and more attention to the protection of personal information. However, the transmission of users’ personal information through social networks will inevitably lead to privacy leakage ...
Yangheran Piao, Kai Ye, Xiaohui Cui
doaj   +1 more source

Challenges for Trusted Computing [PDF]

open access: yes, 2006
The Trusted Computing Group (TCG), an alliance of a large number of IT enterprises, has published a set of specifications aiming at cost-efficient extensions of conventional computer architectures with security-related features and cryptographic mechanisms.
openaire   +2 more sources

DRM, Trusted Computing and Operating System Architecture [PDF]

open access: yes, 2005
Robust technological enforcement of DRM licenses assumes that the prevention of direct access to the raw bit representation of decrypted digital content and the license enforcement mechanisms themselves is possible.
Reid, Jason F.   +3 more
core  

Evaluating GenAI‐produced feedback on undergraduate bioscience essays against good higher education feedback practice

open access: yesFEBS Open Bio, EarlyView.
This pilot study investigates the potential of Generative AI to provide formative feedback to students. ChatGPT was prompted to provide feedback on Year 1 Bioscience essays, which were evaluated against established good feedback practices. GenAI‐authored feedback had useful elements, but was limited in scope. GenAI may have potential to provide instant,
Annabel Court   +3 more
wiley   +1 more source

Enhancing the Security of Deep Learning Steganography via Adversarial Examples

open access: yesMathematics, 2020
Steganography is a collection of techniques for concealing the existence of information by embedding it within a cover. With the development of deep learning, some novel steganography methods have appeared based on the autoencoder or generative ...
Yueyun Shang   +3 more
doaj   +1 more source

Five‐Year Outcomes of Laparoscopic Sphincter‐Preserving Surgery for Rectal Cancer: A Prospective Study in Elderly Vietnamese Patients

open access: yesAging and Cancer, EarlyView.
This prospective study demonstrates that laparoscopic sphincter‐preserving surgery is feasible for elderly patients. While overall survival reaches 70% at 5 years, advanced T‐stage and the omission of neoadjuvant therapy significantly drive recurrence, highlighting the need for personalized geriatric protocols despite logistical challenges.
Huu Duc Ho   +4 more
wiley   +1 more source

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