Results 91 to 100 of about 53,435,330 (271)

Trust and the Goldacre Review: why trusted research environments are not about trust

Journal of Medical Ethics, 2022
Graham, M, Milne, R, Fitzsimmons, P, Sheehan, M   +3 more
openaire   +3 more sources

A Lightweight Procedural Layer for Hybrid Experimental–Computational Workflows in Materials Science

Advanced Engineering Materials, EarlyView.
We unveil a prototype hybrid‐workflow framework that fuses automatedcomputation with hands‐on experiments. Built atop pyiron, a lightweight, parameterized layer translates procedure descriptions into executable manual steps, syncing instrument settings, human interventions, and data capture in real‐time today.
Steffen Brinckmann, Sarath Menon, Raphael Röske, Johannes Steinhülb, Michael Selzer, Jan Janssen, Tilmann Hickel, Ruth Schwaiger, Jörg Neugebauer   +8 more
wiley   +1 more source

The Promises and Perils of Trusted Research Environments

Data Science and machine learning are powered by data, and there is plenty of data today: many human activities are powered by software that generates large quantities of it.While large datasets are constantly generated, putting them in the hands of the engineers and researchers, who can better exploit them, is not always easy.
Gavidia-Calderon, Carlos, Rangel Smith, Camila   +1 more
openaire   +1 more source

Governance Recommendations for Non-Traditional Researchers in Trusted Research Environments (TREs)

, 2022
Trusted Research Environments (TREs) provide secure and trusted infrastructures and services to create an efficient and safe approach to store, link and enable access to data. However, data access to support AI, software development or researchers outside academia or clinical settings has been limited and remains largely aspirational due to a perceived
Mills, Professor Nicholas, Anand, Atul, Harrison, Kathy, Tilbrook, Amy, Dunbar, Stuart, Morris, Carole, Evans, Michelle   +6 more
openaire   +2 more sources

Current Status and Challenges in Data Collection for Aerospace Coatings Deposited by Plasma Spraying

Advanced Engineering Materials, EarlyView.
An innovative approach has been integrated into the GRENAT project to optimize plasma spraying and coating performance. Raw materials are accelerated and melted in the plasma generated by torches, creating coatings. Monitoring sensors collect process data which are combined with ex situ characterization data.
Lila Randriamananjara, Vincent Rat, Quentin Dubreuil, Patrice Valorge, Simon Goutier, Alain Denoirjean, Olivier Messe, Céline Ruelle, Jean‐Philippe Poli   +8 more
wiley   +1 more source

Semantic Modeling in Materials Science and Engineering With Platform MaterialDigital Core Ontology 3.0

Advanced Engineering Materials, EarlyView.
The community‐driven Platform MaterialDigital Core Ontology (PMDco) 3.0 is introduced as a Basic Formal Ontology‐aligned semantic backbone for the processing–structure–properties paradigm in Materials Science and Engineering. Modular engineering, automated releases, and validation workflows are highlighted and key semantic patterns for materials ...
Markus Schilling, Philipp von Hartrott, Jörg Waitelonis, Thomas Hanke, Henk Birkholz, Hossein Beygi Nasrabadi, Khashayar Razghandi, Kamilla Zaripova, Felix Thonagel, Fabian Neuhaus, Martin Glauer, Lars Vogt, Harald Sack, Lutz Mädler, Bernd Bayerlein, Chris Eberl   +15 more
wiley   +1 more source

Towards a UK federation of trusted research environments

International Journal of Population Data Science
ObjectivesPhase 1 of the DARE UK programme concluded in 2024 with a portfolio of architectures, designs and proofs-of-concept for a national federated network of trusted research environments (TREs). We present the current state of the UK’s journey towards a TRE federation. MethodsOur approach was four-fold.
Rob Baxter, null DARE UK Delivery Team
openaire   +1 more source

3D‐Printed Titanium Gyroid Scaffold Structure Integrated With Tough Hybrid Materials for Cartilage Replacement

Advanced Engineering Materials, EarlyView.
This study proposes a potential device design for joint cartilage replacement. Silica‐polytetrahydrofuran (SiO2‐PolyTHF) hybrids with customizable mechanical properties were developed to mimic the characteristics of a natural meniscus. These were synthesized through a two‐pot sol–gel hybrid process.
Yu‐Chien Lin, Gloria R. Young, Francesca Tallia, Reece N. Oosterbeek, Shaaz Ghouse, Edward Spiers, Nupur Kohli, Tom Briggs, Marc Masen, Siwei Li, Ren‐Jei Chung, Jonathan R. T. Jeffers, Julian R. Jones   +12 more
wiley   +1 more source

3D Bioprinted Glioblastoma Multiforme Models: How the Extracellular Matrix Glycosignature Influences Drug Response

Advanced Functional Materials, EarlyView.
Aberrant glycosylation in the glioblastoma tumor microenvironment drives therapeutic resistance. Here, a 3D bioprinted model was engineered by incorporating α‐NeuNAc‐(2→3)‐β‐D‐Gal‐ and chondroitin sulfate. Combined multiplex immunofluorescence and synchrotron‐based nanoCT analysis revealed that glycan‐matrix interactions dictate specific drug‐escape ...
Francesca Cadamuro, Marco Piazzoni, Ilaria Borghi, Alberto Baeri, Alessandro Fumagalli, Federica Perillo, Hafiz Muhammad Fahad, Martina Ghizzi, Luca Crippa, Gabriella Nicolini, Angela Bentivegna, Daniele Ramazzotti, Valentina Zuliani, Mirko Rivara, Carlo Giorgio Giussani, Andrea Di Cristofori, Guido Cavaletti, Federica Facciotti, Sobhan Sheikhi, Claire Seydoux, Murielle Salome, Peter Cloetens, Alberto Bravin, Paola Coan, Francesco Nicotra, Laura Russo   +25 more
wiley   +1 more source

Trusted CI - The NSF Cybersecurity Center of Excellence: Award Year 1 Report [PDF]

, 2020
Trusted CI was renewed as the NSF Cybersecurity Center of Excellence on October 1st, 2020. This report covers 3 quarters of Trusted CI's first year (January 1, 2020-September 30, 2020) operating under a new NSF award, covering Trusted CI's ...
Welch, Von
core   +1 more source