Results 61 to 70 of about 437,233 (263)

Towards a Theory of Trusted Performance in Software Development Projects [PDF]

, 2014
Within the software development discipline, teams are created and disintegrated at an extremely rapid pace. IT organizations are therefore looking at ways to create an environment of greater performance in a shorter period of time.
Jenkins, Jim, Steinke, Gerhard
core   +1 more source

Trusted Research in the Public Eye: A toolkit for public engagement for trusted research environments (TREs).

, 2022
Public opinion regarding the use and reuse of sensitive and personal data is very influential e.g. Care.data and the recent GP Data for Planning Research system which has been delayed for several months after launch to clarify data protection fears. Work by the Wellcome Trust’s Understanding Patient Data (UPD) programme has shown that active engagement
Cole, Christian, Beggs, Jillian, Chuter, Anthony, Gao, Chuang, Li, Simon, Sutherland, James   +5 more
openaire   +1 more source

TREEHOOSE - an Open Source, Cloud-based Trusted Research Environment

, 2022
Analysis of sensitive data for the purpose of national statistics, social policy and healthcare research is challenging as it requires significant governance and ethical oversight. Where and how the analysis is performed is controlled by the data controller as the data cannot be freely shared often resides within a monolithic computing environment ...
Li, Simon, Gao, Chuang, Sutherland, James, Jefferson, Emily, Cole, Christian   +4 more
openaire   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

A UK Specification for Trusted Research Environments

International Journal of Population Data Science
ObjectivesThe need for Trusted Research Environments (TREs) is clear. Several influential reports have highlighted that personal or sensitive data which have been collected for operational, commercial or governmental reasons need to be managed securely in an environment that encourages best practices.
Sood, Hari, Li, Simon, Machin, Tim, Oldfield, Katie, Chuter, Antony, Beggs, Jillian, Coleman, Sonya, Kerr, Dermot, Chalstrey, Ed, Craddock, Matthew, Madge, Jim, Sarmiento-Perez, David, Robinson, James, O’Donovan, Cian, O’Reilly, Martin, Cole, Christian   +15 more
openaire   +3 more sources

Next‐generation proteomics improves lung cancer risk prediction

Molecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj, Clara Frick, Ben Schöttker, Bernd Holleczek, Hermann Brenner   +4 more
wiley   +1 more source

Blockchain-Based Federated Learning System: A Survey on Design Choices

Sensors, 2023
The vanilla federated learning is made for a trusted environment, while in contrast, its actual use cases require collaborations in an untrusted setting.
Yustus Eko Oktian, Sang-Gon Lee
doaj   +1 more source

SATRE – Standardised Architecture for Trusted Research Environments (Kick off)

, 2023
Grant: UK Research and Innovation: SATRE - Standardised Architecture for Trusted Research ...
Chalstrey, Ed, Cole, Christian, Coleman, Sonya, Craddock, Matthew, Hetherington, James, Kerr, Dermot, Li, Simon, Madge, Jim, O'Donovan, Cian, Oldfield, Katie, O'Reilly, Martin, Sarmiento-Perez, David, Sood, Hari, Swanepoel, Nel   +13 more
openaire   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

Trusted Computing and Secure Virtualization in Cloud Computing [PDF]

, 2012
Large-scale deployment and use of cloud computing in industry is accompanied and in the same time hampered by concerns regarding protection of data handled by cloud computing providers.
Paladi, Nicolae
core   +2 more sources