Results 51 to 60 of about 2,008,551 (307)
The role and implications of mammalian cellular circadian entrainment
FEBS Letters, EarlyView.At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley +1 more source
Molecular bases of circadian magnesium rhythms across eukaryotes
FEBS Letters, EarlyView.Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
Towards FollowMe User Profiles for Macro Intelligent Environments [PDF]
, 2012 We envision an Ambient Intelligent Environment as an environment with technology embedded within the framework of that environment to help enhance an users experience in that environment.
Al Malaise Al Ghamdi, A +3 more
core
Obligations of trust for privacy and confidentiality in distributed transactions [PDF]
, 2009 Purpose – This paper aims to describe a bilateral symmetric approach to authorization, privacy protection and obligation enforcement in distributed transactions.
Anne Anderson +4 more
core +1 more source
Governance Recommendations for Non-Traditional Researchers in Trusted Research Environments (TREs)
, 2022 Trusted Research Environments (TREs) provide secure and trusted infrastructures and services to create an efficient and safe approach to store, link and enable access to data. However, data access to support AI, software development or researchers outside academia or clinical settings has been limited and remains largely aspirational due to a perceived
Mills, Professor Nicholas +6 more
openaire +1 more source
Screening for lung cancer: A systematic review of overdiagnosis and its implications
Molecular Oncology, EarlyView.Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz +12 more
wiley +1 more source
, 2022 Public opinion regarding the use and reuse of sensitive and personal data is very influential e.g. Care.data and the recent GP Data for Planning Research system which has been delayed for several months after launch to clarify data protection fears. Work by the Wellcome Trust’s Understanding Patient Data (UPD) programme has shown that active engagement
Cole, Christian +5 more
openaire +1 more source
TREEHOOSE - an Open Source, Cloud-based Trusted Research Environment
, 2022 Analysis of sensitive data for the purpose of national statistics, social policy and healthcare research is challenging as it requires significant governance and ethical oversight. Where and how the analysis is performed is controlled by the data controller as the data cannot be freely shared often resides within a monolithic computing environment ...
Li, Simon +4 more
openaire +1 more source
SoK: Understanding the Prevailing Security Vulnerabilities in TrustZone-assisted TEE Systems
IEEE Symposium on Security and Privacy, 2020 Hundreds of millions of mobile devices worldwide rely on Trusted Execution Environments (TEEs) built with Arm TrustZone for the protection of security-critical applications (e.g., DRM) and operating system (OS) components (e.g., Android keystore).
David Cerdeira +3 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués +3 more
wiley +1 more source