Results 71 to 80 of about 2,440,217 (310)

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

PLURALISM ABOUT TRUTH IN EARLY CHINESE PHILOSOPHY: A REFLECTION ON WANG CHONGS APPROACH [PDF]

open access: yes, 2011
The debate concerning truth in Classical Chinese philosophy has for the most part avoided the possibility that pluralist theories of truth were part of the classical philosophical framework. I argue that the Eastern Han philosopher Wang Chong (c.
McLeod, Alexus
core   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Twitter (X) and the Commercial Determinants of Health: Characterizing the Most Amplified, Influential, and Connected Voices Driving Twitter Discourse About Tobacco Regulatory Policy From September 2019 to July 2021

open access: yesSocial Media + Society
Tobacco content on Twitter (X) generally opposes regulation. Although a near real-time data source of the public’s response to prominent events heightens the allure of extrapolating public sentiment from Twitter content, tobacco policy sentiment on the ...
Nathan A. Silver   +6 more
doaj   +1 more source

Truth and Consequences [PDF]

open access: yes, 2000
International ...
Bardsley, Patrick   +2 more
core   +5 more sources

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Realism and Theories of Truth [PDF]

open access: yes, 2018
The topic of truth has long been thought to be connected to scientific realism and its opposition. In this essay, I discuss the various ways that truth might be related to realism.
Asay, Jamin
core  

Copyright and truth [PDF]

open access: yes, 2011
Copyright @ 2011 Berkeley Electronic PressThis Article calls into question the primary meaning of copyright law. It argues that copyright is not primarily a legal instrument, but rather a fundamental mode of human existence.
Borghi, MA
core   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Truths [PDF]

open access: yesPalliative and Supportive Care, 2021
openaire   +2 more sources

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