Results 1 to 10 of about 2,686 (230)

Effect of time of treatment on the efficacy of trypanocides in rats experimentally infected with Trypanosoma brucei brucei

Notulae Scientia Biologicae, 2023
The effect of treatment time on the efficacy of trypanocides in rats experimentally infected with Trypanosoma brucei brucei was assessed. The thirty albino rats utilized in this study were divided into six groups, each with five rats.
I. Ezeh, C. N. Iheagwam, Chukunonso F. Obi, M. Okpala, G. E. Aneru, Charles O. Agbaeze, R. Ezeokonkwo, D. Onah   +7 more
semanticscholar   +3 more sources

A cross-sectional study on the use and misuse of trypanocides in selected pastoral and agropastoral areas of eastern and northeastern Tanzania

Parasites & Vectors, 2017
Tsetse-borne African animal trypanosomosis (AAT) greatly influences livestock distribution and significantly slows livestock productivity in sub-Saharan Africa.
Anna F. Ngumbi, R. S. Silayo
semanticscholar   +3 more sources

Aberrant use and poor quality of trypanocides: a risk for drug resistance in south western Ethiopia

BMC Veterinary Research, 2018
BackgroundTrypanocidal drugs have been used to control African animal trypanosomosis for several decades. In Ethiopia, these drugs are available from both authorized (legal) and unauthorized (illegal) sources but documentation on utilization practices ...
T. Tekle, G. Terefe, T. Cherenet, H. Ashenafi, K. Akoda, A. Têko-Agbo, J. Abbeele, G. Gari, Peter-Henning Clausen, A. Hoppenheit, R. Mattioli, R. Peter, T. Marcotty, G. Cecchi, V. Delespaux   +14 more
semanticscholar   +3 more sources

Mise en évidence d'une résistance aux trypanocides parmi des souches de Trypanosoma congolense récemment isolées au Burkina [PDF]

, 1984
Dix-huit souches de T. congolense ont fait l'objet d'une épreuve de sensibilité à l'acétate de diminazène et à l'isométamidium chez la souris. L'intérêt et les limites de cette épreuve sont discutés. Les 13 souches de T.
Authié, Edith
core   +2 more sources

Effect of treatment with trypanocides on Trypanosoma brucei induced oxidative stress and antioxidant enzyme activities in dogs

Sokoto Journal of Veterinary Sciences, 2021
Oxidative stress and alteration of endogenous antioxidant enzymes play roles in the pathophysiological mechanism of trypanosomosis. The oxidative stress marker: malondialdehyde- MDA and antioxidative stress markers: Serum catalase- CAT, Serum Reduced ...
P. O. Akpa, P. U. Umeakuana, T. Nnaji, B. Anene   +3 more
semanticscholar   +1 more source

Pathogenicity of Philippine and Indonesian Trypanosoma evansi Isolates in Mice and Their Responses to Trypanocides

, 2021
The pathogenicity of 10 isolates of T. evansi collected from  Mindanao, Philippines, and one isolate from East Java, Indonesia was determined and compared.
A. Dargantes, A. H. Wardhana, J. Abella, Milkesidick R Sequito, S. Reid, D. B. Copeman   +5 more
semanticscholar   +1 more source

Integrated cost-benefit analysis of tsetse control and herd productivity to inform control programs for animal African trypanosomiasis [PDF]

, 2018
Animal African trypanosomiasis (AAT) and its tsetse vector are responsible for annual losses estimated in billions of US dollars ($). Recent years have seen the implementation of a series of multinational interventions.
Chilongo, K, Fauron, A, Gilbert, W, Guitian, J, Holt, H R, Meyer, A, Mumba, C, Oumarou,, F   +7 more
core   +1 more source

Eflornithine is a cost-effective alternative to melarsoprol for the treatment of second-stage human West African trypanosomiasis in Caxito, Angola. [PDF]

, 2008
OBJECTIVE: To compare the cost-effectiveness of eflornithine and melarsoprol in the treatment of human African trypanosomiasis. METHOD: We used data from a Médecins Sans Frontières treatment project in Caxito, Angola to do a formal cost-effectiveness ...
Adam, Blum, Burri, Burri, Chappuis, Commission for Macroeconomics and Health, Edejer, Evans, Goldie, Legros, Louis, Lutumba, Matovu, Murray, Murray, Pepin, Pepin, Pepin, Politi, Priotto, Robays, Schmid, Schmid, Stanghellini   +23 more
core   +2 more sources

Safety and efficacy of three trypanocides in confirmed field cases of trypanosomiasis in working equines in The Gambia: a prospective, randomised, non-inferiority trial

PLoS Neglected Tropical Diseases, 2019
Background Globally, working equines have a continued and growing socioeconomic role in supporting the livelihoods of between 300–600 million people in low income countries which is rarely recognised at a national or international level.
A. Raftery, S. Jallow, J. Rodgers, D. Sutton   +3 more
semanticscholar   +1 more source

Past and Ongoing Tsetse and Animal Trypanosomiasis Control Operations in Five African Countries: A Systematic Review [PDF]

, 2016
Background Control operations targeting Animal African Trypanosomiasis and its primary vector, the tsetse, were covering approximately 128,000 km2 of Africa in 2001, which is a mere 1.3% of the tsetse infested area.
Guitian, J, Holt, H R, Meyer, A, Selby, R   +3 more
core   +8 more sources