Results 181 to 190 of about 2,686 (230)

Overview of the chemotherapy research program at ILRAD

open access: yes, 2010
Aliu, Y.O.   +11 more
core  

Economic methods and spatial scales in One Health: Results from a scoping review. [PDF]

open access: yesOne Health
Schmeyers L   +5 more
europepmc   +1 more source
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Methylating agents as trypanocides.

Journal of Medicinal Chemistry, 1990
Methylating agents, such as streptozotocin, procarbazine, N-methyl-N-nitrosourea, dimethyl sulfate, 1,2-dimethylhydrazine, and a series of 1,2-bis(sulfonyl)-1-methylhydrazines synthesized in this laboratory, were evaluated and shown to be therapeutically active against murine models of African trypanosomiasis.
P. Penketh   +4 more
semanticscholar   +3 more sources

Trypanocidal treatment of Chagas disease

Enfermedades infecciosas y microbiologia clinica (English ed.), 2021
Chagas disease is a neglected parasitosis caused by the protozoan parasite Trypanosoma cruzi. This infection is present in most Latin American countries, although, due to migratory movements, it is a growing cause for concern in non-endemic countries. The only two drugs currently available for its treatment-benznidazole and nifurtimox-were marketed 50 ...
Jose A, Pérez-Molina   +3 more
openaire   +3 more sources

Modelling appropriate use of trypanocides to restrict wide-spread multi-drug resistance during chemotherapy of animal African trypanosomiasis

Parasitology, 2018
Trypanocide resistance remains a huge challenge in the management of animal African trypanosomiasis. Paucity of data on the prevalence of multi-drug resistant trypanosomes has greatly hindered optimal veterinary management practices.
Ibrahim I. Wangwe   +5 more
semanticscholar   +1 more source

Metamidium: a New Trypanocidal Drug

Nature, 1958
THIS communication describes a new trypanocide, which has been found to possess considerable potentiality as a curative and as a prophylactic drug, both in laboratory experiments and in field trials carried out in Africa during the past year.
W R, WRAGG   +3 more
openaire   +2 more sources

IMOL 881, a new trypanocidal compound

Acta Tropica, 1993
A new drug molecule (IMOL 881) was synthesized and is showing interesting trypanocidal properties. The test results on animal models indicate activity against several trypanosome species, both in the veterinary and in the human medicine application fields. The species tested so far include: T. evansi, T. equiperdum, T. gambiense and T. rhodesiense. The
L, Maes, E B, Songa, R, Hamers
openaire   +2 more sources

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