Results 21 to 30 of about 2,686 (230)

Longitudinal observational (single cohort) study on the causes of trypanocide failure in cases of African animal trypanosomosis in cattle near wildlife protected areas of Northern Tanzania. [PDF]

PLoS Negl Trop Dis
African animal trypanosomosis (AAT) in cattle is primarily managed through trypanocide administration and insecticide application. Trypanocides can be used for both treatment and prophylaxis, but failure is often reported; this may occur due to ...
Richards S, Pagnossin D, Buyugu PS, Manangwa O, Mramba F, Sindoya E, Paxton E, Torr SJ, Ritchie R, Rossi GE, Anyanwu LN, Barrett MP, Morrison LJ, Auty H.   +13 more
europepmc   +2 more sources

Prevalence of trypanosomosis in camel calves : A pilot study in Laikipia District of Kenya [PDF]

Revue d’Elevage et de Médecine Vétérinaire des Pays Tropicaux, 2000
La trypanosomose est l'une des maladies les plus importantes du chamelon. Elle se présente sous une forme aiguë et est généralement fatale si aucun traitement n'est administré.
Ndung'u, J.M., Njiru, Z.K., Olaho Mukani, W., Ole-Mapeny, I.M., Ouma, J.O.   +4 more
core   +4 more sources

Managing African animal trypanosomiasis in Benin: Knowledge, attitudes, and practices of cattle owners in the West Atacora zone. [PDF]

Vet World
Background and Aim: African animal trypanosomiasis (AAT), transmitted by tsetse flies, severely constrains livestock productivity in sub-Saharan Africa.
Akpo Y, Tonouhewa ABN, Alkoiret T, Kpodekon MT.   +3 more
europepmc   +2 more sources

Transmission des trypanosomoses animales africaines (TAA) et prévalence trypanosomienne dans les cheptels en zone soudanaise de Côte d’Ivoire

Revue Marocaine des Sciences Agronomiques et Vétérinaires, 2023
La situation entomologique et parasitologique des Trypanosomoses Animales Africaines (TAA) a été évaluée en zone soudanaise de Côte d’Ivoire, suite à l’arrêt des activités de lutte dû à la guerre survenue en 2002 dans le pays.
David KOMONO, Loukou YAO, François KOUAME, Biégo GRAGNON   +3 more
doaj   +1 more source

High prevalence of Trypanosoma spp. and apparent trypanocidal drugs inefficacy in cattle in Al Radom National Park, Sudan. [PDF]

Sci Rep
Trypanosomosis is a major infectious disease affecting cattle in Sudan. In South Darfur, data on cattle trypanosomosis has been limited since the Darfur civil war (2003–2007). This study assessed the prevalence and distribution of Trypanosoma spp.
Mohammedsalih KM, Mukhtar MM, Ibrahim AIY, Mohammedain IMI, Juma FR, Ali AA, Elamin EM, Bashar A, von Samson-Himmelstjerna G, Krücken J.   +9 more
europepmc   +2 more sources

‘Antrycide' : A New Trypanocidal Drug [PDF]

Nature, 1949
THE discovery of a new drug, ‘Antrycide'*, showing great promise in comprehensive field trials as a trypanocide, has already been referred to in an announcement from the Colonial Office. This new drug resulted from a systematic study of the chemotherapy of trypanosomiasis in these Laboratories, and although a full account of our researches must await ...
F H S, CURD, D G, DAVEY
openaire   +3 more sources

Spatial–Temporal Variations in Parasitological Prevalence and Host‐Related Risk Factors of Camel Trypanosomiasis and Its Vectors in North Eastern Kenya: A Repeated Cross‐Sectional Study

Journal of Parasitology Research, Volume 2023, Issue 1, 2023., 2023
Camel trypanosomiasis (Surra) is endemic in the Horn of Africa. Understanding the spatiotemporal variations in Surra prevalence, vector dynamics, and host‐related risk factors is important in developing effective control strategies. A repeated cross‐sectional study was conducted to determine the Surra parasitological prevalence, livestock reservoirs ...
Kennedy O. Ogolla, Judith K. Chemuliti, Florence N. Wamwiri, Joanna E. Auma, Richard K. Kurgat, Kennedy B. Wanjala, Lawrence G. Mugunieri, Phylis M. Alusi, Raymond E. Mdachi, Phoebe W. Mukiria, Sylvance O. Okoth, Bernard Marchand   +11 more
wiley   +1 more source

Core‐Shell DNA‐Cholesterol Nanoparticles Exert Lysosomolytic Activity in African Trypanosomes**

ChemBioChem, Volume 23, Issue 20, October 19, 2022., 2022
The bioengineering of synthetic nanoparticles with therapeutic potential for the treatment of African sleeping sickness is reported. The molecules are DNA‐cholesterol amphiphiles, which self‐assemble into micelle‐type nanoparticles with an exterior DNA shell and a lipid core. The particles are constructed to attack two parasite‐specific targets thereby
Robert Knieß, Wolf‐Matthias Leeder, Paul Reißig, Felix Klaus Geyer, H. Ulrich Göringer   +4 more
wiley   +1 more source

Investigation on Prevalence of Canine Trypanosomiasis in the Conservation Areas of Bwindi‐Mgahinga and Queen Elizabeth in Western Uganda

Journal of Parasitology Research, Volume 2022, Issue 1, 2022., 2022
Nowadays, despite the instauration of several control strategies, animal trypanosomiasis continues to be reported all over Uganda. Few canine African trypanosomiasis (CAT) studies have been carried out, yet dogs are known Trypanosoma reservoirs that share identical home ranges with livestock and serve as parasite link between livestock and humans. This
James Robert Ochieng, Marta Planellas Bachs, Anthony Nsubuga, Innocent B. Rwego, John Joseph M. Kisakye, Laura Muro Riba, Jesus Muro Figueres, John Kagira   +7 more
wiley   +1 more source

Design, Synthesis and Biological Activity of C3 Hemisynthetic Triterpenic Esters as Novel Antitrypanosomal Hits

ChemistryOpen, Volume 10, Issue 9, Page 896-903, September 2021., 2021
A library of 12 C3 triterpenic esters was readily synthesized and tested for antiparasitic activity and cytotoxicity evaluation. C3 esterification kept the activity while lowering the cytotoxicity. The most potent antitrypanosomal activity, coupled with great selectivity, was shown by 2‐fluoro phenylpropionate, phenylpropionate and α‐methyl ...
Laura Schioppa, Claire Beaufay, Natacha Bonneau, Marianela Sanchez, Cynthia Girardi, Aurélie Leverrier, Sergio Ortiz, Jorge Palermo, Jacques H. Poupaert, Joëlle Quetin‐Leclercq   +9 more
wiley   +1 more source