Contribuição ao estudo da infecção de morcegos por hemoflagelados do gênero Trypanosoma Gruby, 1843
O presente estudo foi realizado no período de julho de 1983 a dezembro de 1984, nos municípios cearenses de Russas, Palhano, Limoeiro do Norte, Morada Nova, Canindé, Quixadá e Pereiro, os quais correspondem a parte da área endêmica da tripanossomíase ...
Marta E. Fabián
doaj +1 more source
Immunity and immune modulation in Trypanosoma cruzi infection.
Chagas disease is caused by the protozoan Trypanosoma cruzi. The parasite reaches the secondary lymphoid organs, the heart, skeletal muscles, neurons in the intestine and esophagus among other tissues.
F. Cardillo+3 more
semanticscholar +1 more source
Gap junction reduction in cardiomyocytes following transforming growth factor- beta treatment and Trypanosoma cruzi infection [PDF]
Gap junction connexin-43 (Cx43) molecules are responsible for electrical impulse conduction in the heart and are affected by transforming growth factor-beta (TGF-beta).
Becker, D+6 more
core +2 more sources
Histopathologic identification of Trypanosoma cruzi (Chagas') encephalitis in an AIDS patient
Trypanosoma cruzi (Chagas') encephalitis is an uncommon manifestation of T. cruzi infection, typically seen in immunocompromised patients. Encephalitis results from the reactivation of chronic infection predominately in individuals from endemic areas ...
Dimath Alyemni+8 more
doaj
Action of Trypanosoma rangeli in infections with virulent Trypanosoma cruzi populations
In experimental murine infections with Trypanosoma rangeli it has been observed development immune response to Trypanosoma cruzi. The aim of the present work was to analyze the result of antigenic stimuli and the protective effect with T.
MT Paláu+3 more
doaj +1 more source
The protozoan Trypanosoma cruzi is the causative agent of Chagas disease, one of the world’s major neglected infections. Although development of improved antiparasitic drugs is considered a priority, there have been no significant treatment advances in ...
M. Lewis+3 more
semanticscholar +1 more source
Perspectives on the Trypanosoma cruzi-host cell receptor interaction [PDF]
Chagas disease is caused by the parasite Trypanosoma cruzi. The critical initial event is the interaction of the trypomastigote form of the parasite with host receptors. This review highlights recent observations concerning these interactions.
A Belley+108 more
core +1 more source
Machine Learning Models and Pathway Genome Data Base for Trypanosoma cruzi Drug Discovery
Background Chagas disease is a neglected tropical disease (NTD) caused by the eukaryotic parasite Trypanosoma cruzi. The current clinical and preclinical pipeline for T. cruzi is extremely sparse and lacks drug target diversity.
S. Ekins+12 more
semanticscholar +1 more source
Genome-wide analysis of 30 -untranslated regions supports the existence of post-transcriptional regulons controlling gene expression in trypanosomes [PDF]
In eukaryotic cells, a group of messenger ribonucleic acids (mRNAs) encoding functionally interrelated proteins together with the trans-acting factors that coordinately modulate their expression is termed a post-transcriptional regulon, due to their ...
Agüero, Fernan Gonzalo+3 more
core +3 more sources
Remarques sur la culture de Trypanosoma cruzi Chagas [PDF]
H. Gálliard
openalex +1 more source