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Statins do not reduce the parasite burden during experimentalTrypanosoma cruziinfection

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Razzaq S   +7 more
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Trypanosoma cruzi.

Trends in Parasitology, 2019
Trypanosoma cruzi is the etiological agent of American trypanosomiasis, or Chagas disease, and is transmitted mainly by blood-sucking reduviid insects in endemic countries. Metacyclic trypomastigotes released in the feces during the insect blood meal enter a mammalian host through skin wounds or mucosal membranes and invade sur- rounding cells.
N. S. Moretti   +2 more
semanticscholar   +4 more sources

Immunotherapy of Trypanosoma Cruzi Infections

Current Drug Target - Immune, Endocrine & Metabolic disorders, 2002
The protozoan parasite Trypanosoma cruzi, causative agent of Chagas' disease, is transmitted to man and other mammals by triatominae insects, or 'kissing bugs'. Since its discovery in 1909, by Carlos Chagas, this parasite has been the object of several publications in the domains of immunology, cellular biology and of control gene organization ...
Chamond, Nathalie   +2 more
openaire   +4 more sources

Nucleologenesis inTrypanosoma cruzi

Microscopy and Microanalysis, 2016
AbstractNucleolar assembly is a cellular event that requires the synthesis and processing of ribosomal RNA, in addition to the participation of pre-nucleolar bodies (PNBs) at the end of mitosis. In mammals and plants, nucleolar biogenesis has been described in detail, but in unicellular eukaryotes it is a poorly understood process.
Luis Felipe Jiménez-García   +4 more
openaire   +3 more sources

The Trypanosoma cruzi Proteome

Science, 2005
To complement the sequencing of the three kinetoplastid genomes reported in this issue, we have undertaken a whole-organism, proteomic analysis of the four life-cycle stages of Trypanosoma cruzi . Peptides mapping to 2784 proteins in 1168 protein groups from the annotated T. cruzi genome were
Cameron Frank Cavola   +7 more
openaire   +3 more sources

Immunity to Trypanosoma cruzi

1980
Publisher Summary Trypanosoma cruzi (T. cruzi), the causative agent of Chagas disease, is a digenetic trypanosomatid, which circulates in the bloodstream of the vertebrate host as trypomastigotes and has an obligatory intracellular phase in which the parasite multiplies as amastigotes, which differentiate into trypomastigotes.
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The Cytostome of Trypanosoma cruzi and T. conorhini*

The Journal of Protozoology, 1969
SYNOPSIS. A cytostome is described in culture forms and in intracellular stages of Trypanosoma cruzi and in culture forms of T. conorhini. The organelle opens into the flagellar pocket or close to it and runs deeply into the cell.
Regina Vugman Milder, Maria P. Deane
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