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Intermediary metabolism of Trypanosoma cruzi
Parasitology Today, 1994In this article, Julio Urbino discusses the characteristics o f the intermediary metabolism of Trypanosoma cruzi (the causative agent of Chagas disease), which are responsible for the unusual capacity of this parasite to use carbohydrates or amino acids as carbon and energy sources without drastic changes in its catabolic enzyme levels(1-3).
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TRYPANOSOMA CRUZI CRUZI IN THE TISSUES OF THE ARMADILLO
JAMA: The Journal of the American Medical Association, 1923In 1912, Chagas 1 reported finding Trypanosoma cruzi in the hind gut of Triatoma geniculata , which was collected in the burrows of the armadillo ( Tatusia novemcincta ) in the zone in which American trypanosomiasis is endemic. Following this he found the trypanosomes in the blood of the armadillo, from which he was able to infect guinea-pigs, and ...
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Reservosomes of Trypanosoma cruzi
2010Reservosomes are lysosome-related organelles (LROs) of Trypanosoma cruzi with the special capacity of nutrient storage and hydrolase accumulation. They represent the final compartment of epimastigote endocytic pathway and the site of activity of cruzipain, the major T. cruzi protease.
Wanderley de Souza+3 more
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Signaling in Trypanosoma cruzi
2003Many signaling pathways known to be present in metazoans are also present in unicellular organisms, and Trypanosoma cruzi is not an exception. T. cruzi shares key molecules and biochemical pathways with higher eukaryotes. For example, calcium, adenylyl cyclase, guanylyl cyclase, phospholipase C, nitric oxide synthase, protein kinases, and protein ...
Roberto Docampo, Silvia N.J. Moreno
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Signal Transduction in Trypanosoma cruzi
2011Signal transduction plays a key role in regulating important functions in both multicellular and unicellular organisms and largely controls the manner in which cells respond to stimuli. Signal transduction pathways coordinate the functions in different type of cells in animals and control the growth and differentiation in unicellular organisms ...
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Chemotherapy of Trypanosoma cruzi Infections
1975Publisher Summary This chapter discusses the chemotherapy of Trypanosoma cruzi infections. Trypanosoma cruzi is usually transmitted by hematophagous insects (Hemiptera, Reduviidae) which, after a blood meal, eliminate feces containing infective metacyclic trypomastigotes. These metacyclic forms penetrate the vertebrate host either by skin lesions
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Cell Biology of Trypanosoma cruzi
1984Publisher Summary Among the protozoa of the Trypanosomatidae family, a large number of species represent agents of diseases, such as Chagas' disease. This chapter reviews some aspects of the cell biology of Trypanosoma cruzi, giving emphasis to those aspects related to the ultrastructure of pathogenic protozoa. Protozoa of the Trypanosomatidae family
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Energy Metabolism in Trypanosoma cruzi
1992The American trypanosomiasis, Chagas’ disease, affects about 20 million people in Central and South America. The causative agent is a parasitic flagellate, Trypanosoma cruzi, which has a complex life cycle, involving a replicative form, the amastigote, and a nonreplicative form, the bloodstream trypomastigote, in the mammalian host.
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The microdistribution of Trypanosoma cruzi
Transactions of the Royal Society of Tropical Medicine and Hygiene, 1985openaire +3 more sources