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Pathogenic mechanisms of Trypanosoma evansi infections

Research in Veterinary Science, 2012
Insect-borne diseases exact a high public health burden and have a devastating impact on livestock and agriculture. To date, control has proved to be exceedingly difficult. One such disease that has plagued sub-Saharan Africa is caused by the protozoan African trypanosomes (Trypanosoma species) and transmitted by tsetse flies (Diptera: Glossinidae ...
Nathan, Habila   +4 more
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Catabolism of Tryptophan by Trypanosoma evansi

Journal of Eukaryotic Microbiology, 1995
ABSTRACT. Trypanosoma brucei gambiense, which causes human African trypanosomiasis, catabolizes the aromatic amino acid tryptophan via an initial aminotransferase catalyzed reaction to form several indole end products, which have been suggested to contribute to the pathogenesis of trypanosomiasis. To determine if this same pathway exists in T. evansi,
A, el Sawalhy   +3 more
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Drug sensitivity of Chinese Trypanosoma evansi and Trypanosoma equiperdum isolates

Veterinary Parasitology, 1994
The drug sensitivities of eleven Trypanosoma evansi isolates from China were examined using two different in vitro assays, a 3H-hypoxanthine incorporation assay and a long incubation low inoculation test (LILIT). Better discrimination of the drug susceptibility of the strains was observed with the LILIT.
R, Brun, Z R, Lun
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Population sub-structuring among Trypanosoma evansi stocks

Parasitology Research, 2007
To investigate the population genetic structure of Trypanosoma evansi from domesticated animals, we have analysed 112 stocks from camels, buffaloes, cattle and horses using the tandemly repeated coding sequence (MORF2) and minisatellite markers 292 and cysteine-rich acidic integral membrane protein (CRAM).
Njiru, Z., Constantine, C.C.
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Drug-resistance intrypanosoma evansi

Tropical Animal Health and Production, 1971
Eleven strains ofT. evansi breaking through prophylaxis with quinapyramine suraminate were tested for development of resistance to suramin, quinapyramine, and four strains also to diminazene. It was noted that a variable degree of resistance had developed to the former two drugs but not to diminazene.
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Enzootiology of Trypanosoma evansi in Pantanal, Brazil

Veterinary Parasitology, 2004
In order to better understand the enzootiology of trypanosomiasis caused by Trypanosoma evansi in the Brazilian Pantanal we examined domestic and wild mammals by microhematocrit centrifuge technique (MHCT), immunofluorescence antibody test (IFAT) and polymerase chain reaction (PCR). T. evansi infection was detected in all species sampled with exception
H M, Herrera   +6 more
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Trypanosoma evansi control and containment in Australasia

Trends in Parasitology, 2002
Animal trypanosomosis caused by Trypanosoma evansi is endemic throughout Southeast Asia, where it is an important constraint on the productivity of smallholder livestock. In the past decade, T. evansi has emerged as a serious threat to the viability of smallholder livestock industries in the Philippines and causes severe disease outbreaks with high ...
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Biochemical changes in cats infected with Trypanosoma evansi

Veterinary Parasitology, 2010
This study aimed at evaluating biochemical changes of cats (Felis catus) experimentally infected with Trypanosoma evansi. Seven animals were infected with 10(8) blood trypomastigotes per animal and six were used as controls. Blood smears were performed daily for 56 days and the hepatic, renal and muscular parameters in blood serum were evaluated at ...
Aleksandro S, Da Silva   +10 more
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Biochemical detection of adenosine deaminase in Trypanosoma evansi

Experimental Parasitology, 2011
Biochemical and molecular research on parasites has increased considerably in trypanosomes in the recent years. Many of them have the purpose of identify areas, proteins and structures of the parasite which are vulnerable and could be used in therapy against the protozoan.
Aleksandro S, Da Silva   +10 more
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การวิเคราะห์ความหลากหลายทางพันธุกรรมของเชื้อ Trypanosoma evansi ด้วยวิธีปฏิกิริยาลูกโซ่โพลีเมอเรส

โรคเซอราเกิดจากเชื้อ Typanosoma evansi ซึ่งเป็นโปรโตซัวที่เป็นปรสิตในสัตว์เลี้ยงลูกด้วยน้ำนมหลายชนิด ก่อให้เกิดอาการทางคลินิกที่หลากหลายตั้งแต่ การติดเชื้อแบบเรื้อรังในสุนัขหรือสุกร จนถึงการติดเชื้อแบบเฉียบพลันรุนแรงในม้า ในการศึกษาครั้งนี้ทำการศึกษาเชื้อ T. evansi ที่พบในประเทศไทย 5 isolates โดยใช้วิธีทางอณูชีววิทยาด้วยกัน 3 ทดลอง โดยมีวัตถุประสงค์เพื่
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