Results 141 to 150 of about 45,242 (261)

Overproduction and Characterization of Recombinant Soluble Trypanosoma brucei Phospholipase A2

Engineering in Life Sciences
Trypanosoma brucei phospholipase A2 (TbPLA2) is a validated drug target but the difficulty in expressing its soluble recombinant protein has limited its exploitation for drug and vaccine development for African and American trypanosomiases.
Oluwafemi Abiodun Adepoju, Daniel Quinnell, Harshverdhan Sirohi, Emmanuel Amlabu, Abdullahi Balarabe Sallau, Abdulrazak Ibrahim, Sunday Ene‐Ojo Atawodi, Mohammed Nasiru Shuaibu, Geoffrey Chang, Emmanuel Oluwadare Balogun   +9 more
doaj   +1 more source

Apolipoprotein L1 (APOL1): Consideration of Molecular Evolution, Interaction with APOL3, and Impact of Splice Isoforms Advances Understanding of Cellular and Molecular Mechanisms of Cell Injury

Cells
The Apolipoprotein L1 (APOL1) innate immunity gene product represents the sole member of the APOL gene family in humans capable of secretion into circulation, thereby mediating the trypanolysis of T. brucei brucei.
Razi Khalaila, Karl Skorecki
doaj   +1 more source

Trypanosomiasis [PDF]

Postgraduate Medical Journal, 1938
openaire   +2 more sources

Trypanosomiasis in Britain [PDF]

BMJ, 1965
openaire   +2 more sources

TRYPANOSOMIASIS ON THE CONGO [PDF]

BMJ, 1903
openaire   +2 more sources

A molecular mechanism for eflornithine resistance in African trypanosomes [PDF]

, 2010
Human African trypanosomiasis, endemic to sub-Saharan Africa, is invariably fatal if untreated. Its causative agent is the protozoan parasite Trypanosoma brucei.
Creek, Darren, Burchmore, Richard J S, Vincent, Isabel M, Watson, David G, Barrett, Michael P, Kamleh, Mohammed A, Woods, Debra J, Wong, Pui Ee   +7 more
core  

Oral fexinidazole for late-stage African Trypanosoma brucei gambiense trypanosomiasis: a pivotal multicentre, randomised, non-inferiority trial.

The Lancet, 2018
V. K. B. K. Mesu, Wilfried Mutombo Kalonji, Clélia Bardonneau, Olaf Valverde Mordt, S. Blesson, F. Simon, Sophie Delhomme, Sonja Bernhard, Willy Kuziena, J. Lubaki, Steven Lumeya Vuvu, Pathou Nganzobo Ngima, Hélène Mahenzi Mbembo, M. Ilunga, Augustin Kasongo Bonama, Josué Amici Heradi, Jean Louis Lumaliza Solomo, Guylain Mandula, Lewis Kaninda Badibabi, F. Dama, Papy Kavunga Lukula, D. Tete, C. Lumbala, B. Scherrer, N. Strub-Wourgaft, A. Tarral   +25 more
semanticscholar   +1 more source

Epidemiology of human African trypanosomiasis

, 2014
Jose R Franco,1 Pere P Simarro,1 Abdoulaye Diarra,2 Jean G Jannin1 1World Health Organization, Control of Neglected Tropical Diseases, Innovative and Intensified Disease Management, Geneva, Switzerland; 2World Health Organization, Inter Country Support ...
Franco JR, Simarro PP, Diarra A, Jannin JG   +3 more
core  

Forgotten People, Forgotten Diseases: The Neglected Tropical Diseases and Their Impact on Global Health and Development

Emerging Infectious Diseases, 2009
Charles Ben Beard
doaj   +1 more source

Admission haemoglobin and albumin as correlates of central nervous system inflammation in <i>rhodesiense human African trypanosomiasis</i> at Rumphi District Hospital, Malawi. [PDF]

J Public Health Afr
Nyirenda WT, Mapahla L, Dounebaine B, Dereje N, Nyasulu PS.   +4 more
europepmc   +1 more source