Results 331 to 340 of about 712,349 (416)

Genetics and clinical implications of SPINK1 in the pancreatitis continuum and pancreatic cancer. [PDF]

Hum Genomics
Wang QW, Zou WB, Masson E, Férec C, Liao Z, Chen JM.   +5 more
europepmc   +1 more source

CXCL13 Damages Blood Spinal Cord Barrier by Promoting RNF6/Sqstm1‐Ubiquitination Induced Autophagy in Experimental Allergic Encephalomyelitis

Advanced Science, EarlyView.
In multiple sclerosis, the disruption of the blood‐spinal cord barrier (BSCB) induced by CXCL13 facilitates the infiltration of inflammatory cells into the central nervous system, resulting in demyelination and neuronal injury. Mechanistically, the deleterious impact of CXCL13 on the BSCB is associated with a reduction in tight junction protein ...
Jingjing Han, Rui Hong, Cong Cao, Wanhua Feng, Wei Zhuang, Gui Wang, Jingchao Tang, Ya Yang, Chu Zhang, Aihua Zhou, Xuebin Qu   +10 more
wiley   +1 more source

Amylase/trypsin-inhibitor content and inhibitory activity of German common wheat landraces and modern varieties do not differ. [PDF]

NPJ Sci Food
Jahn N, Geisslitz S, Konradl U, Fleissner K, Scherf KA.   +4 more
europepmc   +1 more source

Trypsin-Plasmin Inhibitors from Leeches Isolation, Amino Acid Composition, Inhibitory Characteristics [PDF]

, 1971
Fink, Edwin, Fritz, Hans, Gebhardt, Maria, Meister, Renate   +3 more
core  

A Porphyrin Nanomaterial for Photoimmunotherapy for Treatment of Melanoma

Advanced Science, EarlyView.
The TPC@OVA NPs are developed as dual‐functional nanomaterials combining phototherapy and immunotherapy for melanoma treatment. This system effectively ablates primary tumors, induces immunogenic cell death, promotes dendritic cell maturation, and enhances T cell activation.
Zhuang Fan, Qing Pei, Haojie Sun, Haiyan Zhang, Zhigang Xie, Tao Zhang, Chong Ma   +6 more
wiley   +1 more source

Protease‐Mediated Synthesis of Zein Nanofibrils: From Structural Elucidation to Functional Application

Advanced Science, EarlyView.
The globular shape and hydrophobicity of zein made it unsuitable to be processed in pure aqueous environment. Pepsin‐mediated hydrolysis converts zein into water‐soluble and fibril‐forming peptides with a bioconversion rate exceeding 70%, enabling the self‐assembly of amyloid‐like nanofibrils.
Mingqin Li, Tonghui Jin, Simone Wüthrich, Jiangtao Zhou, Qiyao Sun, Ting Li, Zhou Dong, Eva Maria Zunzuneigui Bru, Raffaele Mezzenga   +8 more
wiley   +1 more source

Agromorphological and biochemical characterization of mutagens induced M3 mutant lines of grasspea. [PDF]

Sci Rep
Singh PK, Singh A, Kumar V, Sadhukhan R, Jha RK, Siddiqui MH, Khan S.   +6 more
europepmc   +1 more source

Proteinase Inhibitors from Dog Submandibular Glands [PDF]

, 1971
Fink, Edwin, Fritz, Hans, Hochstrasser, Karl, Jaumann, Eugen, Meister, Renate, Pasquay, Peter   +5 more
core  

Nuclear Translocation of S100A9 Triggers Senescence of Human Amnion Fibroblasts by De‐Repressing LINE1 Via Heterochromatin Erosion at Parturition

Advanced Science, EarlyView.
This study shows that the classical secretory protein S100 calcium‐binding protein A9 (S100A9) can translocate to the nucleus upon de‐phosphorylation at Thr 113 in human amnion fibroblasts at parturition, where S100A9 induces heterochromatin erosion through segregation of the heterochromatin maintenance protein, resulting inLong Interspersed Nuclear ...
Fan Zhang, Meng‐Die Li, Fan Pan, Wen‐Jia Lei, Yang Xi, Li‐Jun Ling, Leslie Myatt, Kang Sun, Wang‐Sheng Wang   +8 more
wiley   +1 more source