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This study reveals that Alzheimer's disease–linked APP expression in bone‐forming cells drives skull bone marrow remodeling and alters its vascular connections to the brain. These changes disrupt immune cell trafficking, cerebral blood flow, and cognition. Targeting bone marrow macrophages restores brain function, highlighting a previously unrecognized
Lei Xiong +6 more
wiley +1 more source
Antifungal activity of a trypsin inhibitor from Salvia hispanica L. (chia) seeds against fluconazole-resistant strains of Candida spp. and evaluation of its toxicity in vitro. [PDF]
Nogueira FC +10 more
europepmc +1 more source
The Preventive Effect of Urinary Trypsin Inhibitor on Postoperative Cognitive Dysfunction, on the Aspect of Behavior, Evaluated by Y-Maze Test, via Modulation of Microglial Activity. [PDF]
Cho EH +6 more
europepmc +1 more source
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Crystal structure of a Kunitz-type trypsin inhibitor from Erythrina coffra seeds
Journal of Molecular Biology, 1991Silvia Onesti, Peter Brick, D M Blow
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