Results 201 to 210 of about 161,637 (261)

An Autolysis-Derived Trypsin Peptide Disrupts Digestive Homeostasis and Reduces Fitness in <i>Spodoptera Frugiperda</i> Caterpillars. [PDF]

ACS Omega
Paulo DGS, Meriño-Cabrera Y, Severiche-Castro J, Braga PF, Pereira GDS, da Silva LL, Wurlitzer WB, Schneider JR, Dos Santos EGD, Ferla NJ, Serrão JE, de Andrade RJ, Brustolini OJB, Júnior NRDS, Ramos HJO, Oliveira MGA.   +15 more
europepmc   +1 more source

Genetic Ablation and Multi‐Omics Profiling Reveal CEP55 as a Key Driver of Tumorigenesis in Diverse Cancer Models

Advanced Science, EarlyView.
Genetic ablation of Cep55 in Pten‐deficient mouse models delays tumorigenesis. Integrated multi‐omics analyses (proteomics, phosphoproteomics, and spatial transcriptomics) reveal that CEP55 regulates oncogenic signaling (RAS/ERK, PI3K/AKT), integrin/FAK‐mediated adhesion, extracellular matrix (ECM) remodeling, and endocytosis.
Behnam Rashidieh, Yuanhao Yang, Amanda Louise Bain, Phillip Theron, Catharina Vosloo, Sahar Keshvari, Parinaz Ahangar, Brydie Bowden, Simon M. Tria, Ben B. Wang, Sandra Isenmann, Nicholas J. Westra van Holthe, Zherui Xiong, Hani Vu, Sowmya Sharma, Asmerom Sengal, J. Alejandro Lopez, John Finnie, Antonella Papa, Pascal H.G. Duijf, Quan Nguyen, Pirjo M. Apaja, Kum Kum Khanna   +22 more
wiley   +1 more source

Fermentation as a Lever to Enhance Legume Proteins: From Antinutritional Factors to Improved Quality. [PDF]

Molecules
Smaoui S, Moin A, Chtourou H, Ben Braïek O, Fourati M, Varzakas T.   +5 more
europepmc   +1 more source

ICOS‐ImmunoPET Monitors T Cell Activation After Combination Immune Checkpoint Blockade in a Mouse Model of Melanoma Brain Metastasis

Advanced Science, EarlyView.
ICOS‐immunoPET noninvasively visualizes activated T cells in melanoma brain metastases following combined anti‐PD‐1/anti‐CTLA‐4 therapy. Clinical translation of this imaging approach may improve patient stratification and treatment monitoring and serve as a quantitative imaging endpoint to support immunotherapy development and clinical trials in brain ...
Renesmee C. Kuo, Rohit Verma, Sydney C. Nagy, Mausam Kalita, Samuel Aubert, Josué Ballesteros‐Álvarez, Pedro Machado Almeida, Hannes Vogel, Israt S. Alam, Michael Lim, Michelle L. James   +10 more
wiley   +1 more source

Molecular modeling and quantum chemical calculation study of derived peptides from a Bowman-Birk inhibitor in complexes with trypsin. [PDF]

J Mol Model
Benício LFMA, Nascimento ÉCM, de Freitas SM, Martins JBL.   +3 more
europepmc   +1 more source

Targeted Reduction of Specific Antinutritional and Allergen-Associated Proteins to Advance Soybean Seed Quality. [PDF]

Int J Mol Sci
Krishnan HB, Kim W, Kim S, Nguyen TT.
europepmc   +1 more source

Repurposing screens reveal a role for PKCη and NF1 in SARS-CoV-2 infection. [PDF]

PLoS Pathog
Acuña JA, Miller J, Bhutda S, Ayyanathan K, Kamalia B, Whig K, Nguyen D, Zhu Y, Laleu B, Wells T, Samby K, Pekosz A, Schultz DC, Cherry S.   +13 more
europepmc   +1 more source

Fragment-Based Discovery of KLK6 and KLK7 Inhibitors. [PDF]

J Chem Inf Model
de Freitas RF, Soualmia F, Boumali R, Harrak Y, Amri CE.   +4 more
europepmc   +1 more source