Results 171 to 180 of about 16,690 (208)
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Tryptophan uptake and tryptophan oxygenase activity in mice
Biochemical and Biophysical Research Communications, 1970Abstract Groups of mice were injected intraperitoneally with L-tryptophan, 1 mg/gm body weight, and maintained at room temperature (22° C) or exposed to acute heat stress (36° C). In the heat-stressed animals, plasma tryptophan levels were lower at each time interval studied when compared with room temperature controls; however, both hepatic ...
R P, Francesconi, M, Mager
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Premature induction of hepatic tryptophan oxygenase
Neurochemical Research, 1976Subcutaneous administration of hydrocortisone acetate to the newborn rat produces a premature induction of hepatic tryptophan oxygenase consisting of a transient rise in activity 6-8 h after treatment, followed by a second sustained rise beginning 40 h later, which plateaus at 10 days of age.
A, Yuwiler, B L, Bennett, E, Geller
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Ethyl alcohol and liver tryptophan oxygenase
Biochemical Medicine, 1976Abstract The activity of the enzyme tryptophan oxygenase increases after an acute dose of alcohol, reaching the maximum level 5 hr after injection. This is true for both the apoenzyme and the holoenzyme. The activity comes back to near normal level 9 hr after injection.
G K, Kumar, V M, Sardesai
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The activation of the enzyme tryptophan oxygenase
Comparative Biochemistry and Physiology Part B: Comparative Biochemistry, 1971Abstract 1. 1. The activation of the liver enzyme tryptophan oxygenase has been studied in the frog and rat. 2. 2. Hematin, an iron protoporphyrin, activates the rat enzyme but has no effect on the frog enzyme. 3. 3. Microsomes and mitochondria from both species contain an activator(s) distinct from hematin which is effective in both rat ...
M, Spiegel +2 more
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Single-wavelength spectrophotometric assay for tryptophan oxygenase
Analytical Biochemistry, 1977Abstract The activity of the enzyme tryptophan oxygenase is determined by a simple sensitive single-wavelength spectrophotometric assay of the rate of formation of two rapidly formed products, N-formylkynurenine and kynurenine. The sum of the concentrations of both products is determined at the wavelength of their isosbestic point, 337 nm, where for ...
J A, Symanski, D A, Bennett
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The Tryptophan oxygenase gene of Anopheles gambiae
Insect Biochemistry and Molecular Biology, 1996The Anopheles gambiae gene encoding tryptophan oxygenase, a homolog of the Drosophila melanogaster vermilion gene, has been molecularly cloned and characterized. Unlike Drosophila, where it is X-linked, the A. gambiae gene maps to chromosome 2R, subdivision 12E, by in situ hybridization to the polytene chromosomes.
O, Mukabayire +4 more
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Chlorpromazine inhibition of tryptophan oxygenase
Biochemical Pharmacology, 1971Abstract The effect of chlorpromazine on the activity of liver tryptophan oxygenase was examined in rat liver homogenates and in perfused rat livers. Chlorpromazine was found to inhibit the enzyme in the assay system (50 per cent inhibition at 3 · 10 −4 M).
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Increase in Tryptophan Oxygenase Activity in Alcoholic Patients
Alcoholism: Clinical and Experimental Research, 1988This study was conducted in order to assess whether chronic excessive alcohol consumption affects the activity of the liver enzyme tryptophan oxygenase which is rate limiting along the most important pathway of catabolism.Five alcoholics were studied twice, once shortly after admission to an Inpatient unit and the second time 1 month later.
L, Buydens-Branchey +5 more
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