Results 111 to 120 of about 1,040,508 (338)

An economic evaluation of laparoscopy and open surgery in the treatment of tubal pregnancy

open access: yesActa Obstetricia et Gynecologica Scandinavica, 1997
Background. Laparoscopy has generally replaced open surgery in the treatment of ectopic pregnancy. This study assesses the impact of the introduction of laparoscopy in the surgical treatment of tubal pregnancy on costs. Methods.
Ben W.J Mol   +6 more
doaj   +1 more source

IGF‐1 Deficiency Serves as an Integrated Biomarker Pathogenic Driver and Predictor in Poor Ovarian Response

open access: yesAdvanced Science, EarlyView.
IGF‐1 deficiency underlies poor ovarian response (POR), as reduced levels in follicular fluid and granulosa cells impair antral follicle formation and compromise reproductive outcomes. Including IGF‐1 as a biomarker significantly enhances the accuracy of models predicting both PORrisk and pregnancy success.
Zhu Hu   +9 more
wiley   +1 more source

Mapping the Non‐Canonical Splicing Variants: Decrypting the Hidden Genetic Architecture of Idiopathic Male Infertility

open access: yesAdvanced Science, EarlyView.
This study highlights the significance of non‐canonical splicing variants in male infertility, a factor often overlooked during the analysis of high‐throughput sequencing data. Incorporating the non‐canonical splicing variants prioritization in the genetic analysis pipeline will increase the genetic diagnosis of patients with male infertility ...
Kuokuo Li   +22 more
wiley   +1 more source

Endothelial Cell‐Specific Molecule‐1 (ESM1): An Endogenous Anticoagulant and Protective Factor in Venous Thrombosis

open access: yesAdvanced Science, EarlyView.
This study identifies ESM1 as an endogenous anticoagulant that modulates venous thrombosis. It shows that ESM1 deficiency triggers vascular occlusion in zebrafish and mice, whereas its restoration or overexpression prolongs clot‐formation time. Mechanistic analyses reveal that ESM1 activates HCII through its dermatan‐sulfate chain, uncovering a ...
Changsheng Chen   +10 more
wiley   +1 more source

The unfortunate twin: A case report of intrapartum diagnosis of heterotopic pregnancy

open access: yesCase Reports in Women's Health
Heterotopic pregnancy is a rare condition characterized by the simultaneous presence of both an intrauterine and an ectopic pregnancy. Most cases are identified during the first trimester.
Mesfin Ayalew Tsegaye   +1 more
doaj   +1 more source

Unruptured Live Ectopic Pregnancy at 11 Weeks of Gestation

open access: yesİstanbul Medical Journal, 2016
Ectopic pregnancy is defined as the implantation of a fertilized ovum at a site other than the uterine endometrium. The fallopian tube is the most common site for ectopic implantation.
Hale Göksever Çelik   +3 more
doaj   +1 more source

Caspase‐3/GSDME‐Mediated Trophoblast Pyroptosis and Reciprocal Macrophage Polarization Contribute to Inflammation in Early‐Onset Preeclampsia

open access: yesAdvanced Science, EarlyView.
In trophoblast cells, T/S (TNFα + SM164) activated caspase‐3, which cleaved GSDME to switch apoptosis to pyroptosis, causing cell swelling, membrane rupture, and release of LDH, HMGB1, IL‐1β and IL‐18. These cytokines induced pro‐inflammatory macrophage polarization, which in turn reinforced pyroptotic signaling in trophoblasts, amplifying systemic ...
Baoying Huang   +15 more
wiley   +1 more source

Choriocarcinoma in tubal pregnancy: A case report. [PDF]

open access: yesClin Case Rep, 2023
Najib FS   +3 more
europepmc   +1 more source

Imaging complications of assisted reproductive procedures [PDF]

open access: yes, 2013
The incidence of assisted conception has increased dramatically in Europe, doubling over the past decade. Assisted reproductive technology (ART) is involved in approximately 1 % of births in the developed world.
Vassallo, Pierre
core  

EIF5A Couples Translational Control With Transcriptional Reprogramming Through Chromocenter Reorganization During Spermiogenesis

open access: yesAdvanced Science, EarlyView.
The translation factor Eukaryotic translation initiation factor 5A (eIF5A) is essential for male fertility in mice. It supports the translation of proteins crucial for heterochromatin organization and acrosome formation. eIF5A deficiency disrupts chromocenter integrity, increases chromatin accessibility, and causes transcriptional dysregulation ...
Yuling Cai   +15 more
wiley   +1 more source

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