Results 31 to 40 of about 22,589 (130)

Nrsn1–Smarcc1 Coupling Regulates Neural Stem Cell Differentiation and Chronic‐phase Recovery After Ischemic Stroke

Advanced Science, EarlyView.
In the post‐stroke brain, Foxa2 induces the transcriptional upregulation of Nrsn1 in NSCs. Nrsn1 functionally couples with Smarcc1, modulating its nuclear availability and protein abundance, thereby influencing Smarcc1‐associated regulatory programs linked to neuronal lineage commitment. Through this coupling, Nrsn1 promotes the differentiation of NSCs
Ruolin Zhang, Chang Liu, Yuneng Zhou, Kaichen Zhao, Muyang Li, Bingcheng Cai, Ying Wang, Zhiyuan Yuan, Zhaoxin Liu, Zilong Yuan, Yao Xiao, Peiyang Zhou, Ke Shui, Wendai Bao, Min Zhang, Jun Qin, Jun Chen, Xin Yang, Zhiqiang Dong   +18 more
wiley   +1 more source

Neuron‐Derived Vesicular circMagi1 Restrains Vascular Repair After Ischemic Stroke by Promoting TRIM65‐Mediated ANXA2 Degradation

Advanced Science, EarlyView.
After ischemic stroke, injured neurons transfer circMagi1 to endothelial cells through extracellular vesicles. Within endothelial cells, circMagi1 binds ANXA2 and enhances its engagement with TRIM65, promoting ANXA2 ubiquitination and proteasomal degradation to constrain angiogenic repair.
Youkun Bi, Qun Liu, Baohua Zou, Wenyuan Wang, Xinlong Qiao, Lin Gao, Chaoxu Miao, Ningning Huang, Shuqing Tang, Rui Guo, Changqing Zeng, Ce Jia, Yuanchao Xue, Xuejun Guo, Jianjun Chen, Huiwen Wang, Guangju Ji   +16 more
wiley   +1 more source

Relationship between chronic endometritis and tubal patency and its influence on pregnancy outcome after tubal recanalization

, 2022
Abstract Study Objective: To explore the relationship between chronic endometritis (CE) and tubal patency, and the influence of chronic endometritis on pregnancy outcome after fallopian tubal recanalization(FTR). Method: We retrospectively analyzed 498 women of childbearing age who underwent laparoscopy and hysteroscopy for infertility.
Yu Sun, Dongyan Li, Shuaihong Zhao, Mukun Yang, Guangxia Cui, Wenpei Bai   +5 more
openaire   +1 more source

Application of Random Forest Algorithm in Pregnancy Prediction after Fallopian Tube Recanalization [PDF]

Zhongguo quanke yixue
Background Protecting female fertility stands as a central goal and vision in a fertility-friendly society, and fallopian tube recanalization offers the possibility of pregnancy for patients with tubal infertility. Objective This study aims to accurately
LIU Feiran, CHEN Minghuang, ZHAO Shuaihong, BAI Wenpei
doaj   +1 more source

Non-tubal Ectopic Pregnancy [PDF]

, 2020
"Non-Tubal Ectopic Pregnancy" is a comprehensive book, written in an organized and concise format. The book offers an immersion into non-tubal ectopic pregnancy and the reader is invited, chapter after chapter, to visit the most important aspects of non ...

core   +1 more source

Engineered immunostimulatory H2O2‐producing microreactors driven by yeast as localized living cancer therapeutics

BMEMat, EarlyView.
Engineered yeast microreactors that produce H2O2 within tumors enable selective cancer cell killing while releasing immunostimulatory components, effectively suppressing local tumor growth and activating systemic antitumor immunity, with further efficacy enhanced by anti‐PD‐1 therapy and transarterial embolization.
Wenqian He, Chunjie Wang, Minming Chen, Weihao Yang, Bin Yu, Yuhang Hu, Hengze Ding, Yifan Yan, Zhijuan Yang, Liangzhu Feng   +9 more
wiley   +1 more source

Roux‐en‐Y gastrojejunostomy and jejunojejunostomy for pyloric obstruction bypass in a horse and a foal

Equine Veterinary Journal, EarlyView.
Abstract Background Gastric outflow obstruction in horses is a rare but challenging condition, often resulting from either congenital anomalies or acquired lesions such as chronic ulceration or pyloric polyps. Conventional surgical bypass procedures, including gastrojejunostomy (GJ) or gastroduodenostomy and less commonly duodenojejunostomy, can ...
Marco Gandini, Nico Bolz, Christian Czech, Myria Hartman, Gessica Giusto   +4 more
wiley   +1 more source

Pregnancy outcome after hystero-salpingo-contrast-sonography (HyCoSy) versus hysterosalpingography (HSG) using different contrast media

Middle East Fertility Society Journal, 2011
Objective: The main conventional imaging modalities used to assess female tubal patency are hysterosalpingography (HSG) and Hystero-salpingo-contrast-sonography (HyCoSy), which could also be used to guide tubal recanalization.
Emad M. Siam
doaj   +1 more source

Single‐Cell RNA Sequencing and Spatial Multiomics Unveil Microglia–Mural Interactions Underlying Notoginsenoside R1 Against Ischemic Stroke

iMetaMed, EarlyView.
Integrated scRNA‐seq and spatial multiomics provide single‐cell and spatial insights into the neuroprotective effects of NGR1, a clinically validated bioactive compound from Panax notoginseng. NGR1 was associated with a shift in microglial transcriptional states away from ischemia‐associated pro‐inflammatory Adam8hi microglia and toward the protective ...
Qikun Zhao, Wenbo Guo, Yanrong Zheng, Guoqian Cui, Bingjie Wan, Shuhui Deng, Hudong Bao, Xiao Tu, Shengshuang Chen, Jie Liao, Xiaohui Fan   +10 more
wiley   +1 more source

Tubal recanalization following sterilization in the era of IVF

Indian Journal of Obstetrics and Gynecology Research, 2019
Introduction: Female sterilization remains the most popular contraceptive method among young Indian women. Among the age group of 15-49, 36% use female sterilization as contraception method. Early marriage, sterilization at young age, high infant and child mortality has led to increase in the need of recanalization in 1-3% of women.
openaire   +1 more source