Results 41 to 50 of about 41,119 (245)

p16Ink4a‐Positive Hepatocytes Drive Liver Fibrosis Through Activation of LIFR Family Pathway

Advanced Science, EarlyView.
This study found that, following the long‐term CCl4 treatment, p16high hepatocytes appeared in zone 3, spatially co‐localizing with fibrotic areas. A specific cluster of p16high hepatocytes upregulated CTF1/LIF expression which induced HSC activation and further liver fibrosis, as revealed by single cell transcriptomic analysis.
Koji Nishikawa, Teh‐Wei Wang, Satoshi Kawakami, Shota Tanimoto, Kiyoshi Yamaguchi, Taketomo Kido, Masamichi Kimura, Tsunekazu Hishima, Yuki T. Okamura, Satotaka Omori, Takumi Iritani, Toshikaze Chiba, Takehiro Jimbo, Michio Katano, Kansuporn Kamataki, Ryoichi Yokoyama, Eigo Shimizu, Kiminori Kimura, Satoshi Yamzaki, Seiya Imoto, Yoichi Furukawa, Atsushi Miyajima, Yoshikazu Johmura, Makoto Nakanishi   +23 more
wiley   +1 more source

Theoretical research on a large beam tunnel, coalesced-mode broadband traveling wave tube

Physics of Plasmas
A coalesced-mode, wide bandwidth traveling wave tube (TWT) with a large beam tunnel is herein investigated for use in millimeter-wave and terahertz amplification sources. The high frequency structure and input–output circuits of the TWT are designed to operate in both mode 1 (coalesced TE10-like mode) and mode 3 (coalesced TM11-like mode) at a same ...
Zhongtao Cui, Xuesong Yuan, Qinwen Xue, Yiwen Le, Yunze Zhu, Matthew Thomas Cole, Yang Yan   +6 more
openaire   +1 more source

Is turbulent mixing a self convolution process ? [PDF]

, 2008
Experimental results for the evolution of the probability distribution function (PDF) of a scalar mixed by a turbulence flow in a channel are presented.
Antoine Venaille, E. O’Brien, H. Schlichting, J. O. Hinze, Joel Sommeria   +4 more
core   +3 more sources

In Situ X‐Ray Tomography and Acoustic Emission Monitoring of Damage Evolution in C/C‐SiC Composites Fabricated by Liquid Silicon Infiltration

Advanced Science, EarlyView.
This study investigates how the internal structure of fiber‐reinforced ceramic composites affects their resistance to damage. By combining 3D X‐ray imaging with acoustic emission monitoring during mechanical testing, it reveals how silicon distribution influences crack formation.
Yang Chen, Renato S. M. Almeida, Stefan Flauder, Guillaume Couégnat, Kamen Tushtev, Jürgen Horvath, Peter Wriggers, Kurosch Rezwan   +7 more
wiley   +1 more source

Diffusive transport and in situ coalescence of magnetic flux tubes. I - Steady state solutions

The Astrophysical Journal, 1985
There is increasing evidence of fibril character in astrophysical magnetic fields. The solar photosphere is an obvious example. We suggest that the hierarchy of magnetic structures observed in the photosphere may be synthesized through the coalescence of the thin (Rroughly-equal2--3 x 10/sup 2/ km), intense (Broughly-equal1--2 x 10/sup 3/ gauss ...
openaire   +1 more source

Stabilization of Single Metal Atoms on Graphitic Carbon Nitride: Synthetic Strategies and Emerging Applications

Advanced Science, EarlyView.
This review highlights recent advancements in stabilizing single metal atoms on graphitic carbon nitride emphasizing innovative synthesis strategies and emerging applications in electrocatalysis, photocatalysis and organic transformations, along with key challenges and future perspective. Abstract Emerging as a new frontier in catalysis science, single‐
Wenyao Zhang, Junjie Cui, Zhenjie Yao, Boyuan Zhu, Nithinraj Panangattu Dharmarajan, Ajayan Vinu, Junwu Zhu   +6 more
wiley   +1 more source

Competition Between Liquid‐Liquid Crystalline Phase Separation (LLCPS) and Liquid‐Liquid Phase Separation (LLPS) in Amyloid Fibril Colloidal Systems

Advanced Science, EarlyView.
This study shows that amyloid fibrils form nematic condensates via liquid–liquid crystalline phase separation (LLCPS). With increasing pH, this transition shifts toward disordered condensates formed through liquid–liquid phase separation (LLPS), in which birefringence with lack of a coherent nematic field symmetry originates from enthalpic fibril ...
Milad Radiom, Raffaele Mezzenga
wiley   +1 more source

A Metal‐Free Carbon Monoxide Prodrug Suppresses Metastasis of Pancreatic and Breast Cancer

Advanced Science, EarlyView.
A metal‐free carbon monoxide (CO) prodrug, CO‐116, delivers controlled systemic CO without inhalation. CO suppresses the HRG1–heme axis, reducing intracellular heme availability. Attenuation of this pathway inhibits metastatic progression in pancreatic and triple‐negative breast cancer models.
Tiantian Zhang, Xiang Chen, Xiaoxiao Yang, Muskan Gori, Rohit Kumar Varshnaya, Dongning Liu, Cheryl Zhang, Michelle Yi Qin Chen, Zhengming Chen, George Zhang, Erika Patel, Qiyue Mao, Tan A. Ince, Chalet Tan, Binghe Wang, Yi‐Chieh Nancy Du   +15 more
wiley   +1 more source

Computational fluid dynamics simulation of bubble coalescence and breakup in an internal airlift reactor: Analysis of effects of a draft tube on hydrodynamics and mass transfer

Applied Mathematical Modelling, 2015
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Ebadi Amooghin, Abtin, Jafari, Somaye, Sanaeepur, Hamidreza, Kargari, Ali   +3 more
openaire   +1 more source

Antideuteron yield at the AGS and coalescence implications

, 2000
We present Experiment 864's measurement of invariant antideuteron yields in 11.5A GeV/c Au + Pt collisions. The analysis includes 250 million triggers representing 14 billion 10% central interactions sampled for events with high mass candidates. We find (
A. Chikanian, A. Hirsch, A. Rimai, A. Rose, A. Slaughter, B. Fadem, B. Kumar, B. Libby, C. Dover, C. Pruneau, F. Rotondo, F. Wohn, G. Smith, G. Van Buren, H. Huang, H. Jaradat, I. Pless, J. Hill, J. Lajoie, J. Nagle, J. Pope, J. Reid, J. Sandweiss, K. Barish, L. Finch, M. Bertaina, M. Munhoz, M. Rabin, M. Tincknell, N. George, N. Porile, P. Fachini, P. Haridas, Q. Li, R. Davies, R. Hoversten, R. Majka, R. Scharenberg, S. Batsouli, S. Bennett, S. Coe, S. Greene, T. Armstrong, T. Cormier, T. Lainis, T. Miller, W. Toothacker, Z. Xu   +47 more
core   +1 more source