Results 101 to 110 of about 189,839 (286)

Highly multiplexed digital PCR assay for simultaneous quantification of variant allele frequencies and copy number alterations of KRAS and GNAS in pancreatic cancer precursors

Molecular Oncology, EarlyView.
Combining melting curve analysis enhances the multiplexing capability of digital PCR. Here, we developed a 14‐plex assay to simultaneously measure single nucleotide mutations and amplifications of KRAS and GNAS, which are common driver genes in pancreatic cancer precursors. This assay accurately quantified variant allele frequencies in clinical samples
Junko Tanaka, Tatsuo Nakagawa, Yusuke Ono, Yoshio Kamura, Takeshi Ishida, Hidemasa Kawabata, Kenji Takahashi, Hiroki Sato, Andrew S. Liss, Yusuke Mizukami, Takahide Yokoi   +10 more
wiley   +1 more source

Anomalous Effects in Air While Cooling Water [PDF]

arXiv, 2008
Water is a unique compound with many anomalies and properties not fully understood. Designing an experiment in the laboratory to study such anomalies, we set up a series of experiments where a tube was placed inside a sealed container with thermocouples attached to the outer surface of the tube and in the air adjacent to the tube.
arxiv  

Investigation of combination of heat storage container and thermosyphon solar system in existence of nanomaterial

Case Studies in Thermal Engineering
This research explores the combination of fins into thermosyphon solar collectors to enhance energy efficiency. The storage system includes a finned container filled with nanomaterial (a blend of Al2O3 nanoparticles and paraffin (RT30)), while the fluid ...
S.M. Mousavi, M. Sheikholeslami
doaj  

Study of a Coil Heat Exchanger with an Ice Storage System

Energies, 2017
In this study, a coil heat exchanger with an ice storage system is analyzed by theoretical analysis, numerical analysis, and experimental analysis. The dynamic characteristics of ice thickness variation is studied by means of unstable heat conduction ...
Yan Li, Zhe Yan, Chao Yang, Bin Guo, Han Yuan, Jian Zhao, Ning Mei   +6 more
doaj   +1 more source

Deep Learning for Estimating the Fill-Level of Industrial Waste Containers of Metal Scrap: A Case Study of a Copper Tube Plant [PDF]

, 2023
Kosmas Alexopoulos, Paolo Catti, Giannis Kanellopoulos, Nikolaos Nikolakis, Athanasios Blatsiotis, K. Christodoulopoulos, Apostolos Kaimenopoulos, Efstathia Ziata   +7 more
openalex   +1 more source

The atypical KRASQ22K mutation directs TGF‐β response towards partial epithelial‐to‐mesenchymal transition in patient‐derived colorectal cancer tumoroids

Molecular Oncology, EarlyView.
TGF‐β has a complex role in cancer, exhibiting both tumor‐suppressive and tumor‐promoting properties. Using a series of differentiated tumoroids, derived from different stages and mutational background of colorectal cancer patients, we replicate this duality of TGF‐β in vitro. Notably, the atypical but highly aggressive KRASQ22K mutation rendered early‐
Theresia Mair, Philip König, Milena Mijović, Jessica Kalla, Anil Baskan, Loan Tran, Kristina Draganić, Pedro Morata Saldaña, Carlos Uziel Pérez Malla, Janette Pfneissl, Andreas Tiefenbacher, Julijan Kabiljo, Velina S. Atanasova, Lisa Wozelka‐Oltjan, Leonhard Müllauer, Michael Bergmann, Raheleh Sheibani‐Tezerji, Gerda Egger   +17 more
wiley   +1 more source

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

Molecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes, Mario Ortega Duran, Solon Karapanagiotis, Alistair Martin, Meiling Gao, Riccardo Masina, Ramona Woitek, James Tanner, Fleur Tippin, Justine Kane, Jonathan Lay, Anja Brouwer, Stephen‐John Sammut, Suet‐Feung Chin, Davina Gale, Dana W. Y. Tsui, Sarah‐Jane Dawson, Nitzan Rosenfeld, Maurizio Callari, Oscar M. Rueda, Carlos Caldas   +20 more
wiley   +1 more source

Volume estimates for unions of convex sets, and the Kakeya set conjecture in three dimensions [PDF]

arXiv
We study sets of $\delta$ tubes in $\mathbb{R}^3$, with the property that not too many tubes can be contained inside a common convex set $V$. We show that the union of tubes from such a set must have almost maximal volume. As a consequence, we prove that every Kakeya set in $\mathbb{R}^3$ has Minkowski and Hausdorff dimension 3.
arxiv  

A Novel Low-Temperature Extrusion Method for the Fused Filament Fabrication of Fluoroelastomer Compounds

Micromachines
In this work, an additive manufacturing process for extruding fully compounded thermosetting elastomers based on fluorine-containing polymer compositions is reported.
Mookkan Periyasamy, Ronald Campbell, Joey M. Mead, David O. Kazmer, ShibShankar Banerjee, AA Mubasshir, Leeda A. Phaen, Stiven Kodra   +7 more
doaj   +1 more source

Five Years' Experience of Modern Shock-Proof and Ray-Proof Containers for Roentgen Therapy Tubes [PDF]

, 1938
R. Thoræus
openalex   +1 more source