Results 41 to 50 of about 146,641 (261)

Tube Expansion Under Various Down-Hole End Conditions

The Journal of Engineering Research, 2013
Fossil hydrocarbons are indispensables commodities that motorize the global economy, and oil and gas are two of those conventional fuels that have been extracted and processed for over a century.
FJ Sanchez, OS Al-Abri
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Optimization of the Attractive Electromagnetic Bulging of Small Tubes Based on Non-Uniform Solenoid Coils

IEEE Access, 2020
The attractive electromagnetic bulging is a novel technology which has unique advantages in the formation of small tube fittings. To generate the attractive electromagnetic force, a dual-frequency current method has been proposed in the existing research
Meng Yang, Jiaying Yan, Xianqi Song, Li Qiu, Jinbo Jiang, Kun Yu, Qi Xiong, Chistear Ahmed Khan   +7 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Experimental Analysis of Oil Cooler Based on Trefoil Screwed Expansion Pipe

Zhileng xuebao, 2015
The traditional oil cooler with smooth tube has low heat transfer coefficient and dead zone in shell side flow, and it easily produces dirt. The trefoil screwed expansion pipe is used to enhance the heat transfer of the traditional oil cooler.
Huang Yuanyuan, Zhou Guoyan, Qian Tailei, An Dongxu, Yang Liu, Zhu Dongsheng   +5 more
doaj  

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Analytical modeling of tube-to-tubesheet joints subjected to plastic deformation and creep

Journal of Advanced Mechanical Design, Systems, and Manufacturing, 2016
The mechanism of failure of heat exchanger and steam generator tube-to-tubesheet joints is related to the level of residual stresses produced in the tube expansion and transition zones during the expansion process and their variation during operation ...
Abdel-Hakim BOUZID, Nor-Eddine LAGHZALE
doaj   +1 more source

Prediction of cycle life of expansion bellows for fixed tube sheet heat exchanger [PDF]

Fracture and Structural Integrity, 2019
Research on determining the lifetime of an expansion bellows designed to compensate the difference in expansion between the shell and the tubes in a fixed tube sheet heat exchanger has never ceased because of its Importance in a heat exchanger.
A. Chouiter, D. Benzerga, A. Haddi, T. Tamine   +3 more
doaj   +1 more source