Results 71 to 80 of about 32,803 (206)

Mediastinal and peripheral lymphadenopathy

The Pan African Medical Journal, 2015
A 32-year-old man, with no history of cigarette smoking, had four weeks history of non productive cough, chest pain and myalgias. Physical examination revealed a painless bilateral cervical lymphadenopathy, the respiratory examination was normal.
Khaoula Elatiqi, Najiba Yassine
doaj   +1 more source

Mycobacterium tuberculosis complex detected by modified fluorescent in situ hybridization in lymph nodes of clinical samples

Journal of Infection in Developing Countries, 2011
Introduction:  Lymph node tuberculosis (TB) is the leading cause of extrapulmonary tuberculosis and is the most frequently identified type in Aguascalientes, Mexico.
Juan Rodriguez-Nuñez, Francisco J Avelar, Francisco Marquez, Bruno Rivas-Santiago, Cesar Quiñones, Alma L. Guerrero-Barrera   +5 more
doaj   +1 more source

Immunostimulatory and Immunodynamic Modeling Analysis to Determine a Plausible Starting Dose of mRNA‐4359 for Use in First‐In‐Human Trials

CPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 2, February 2026.
ABSTRACT The investigational antigen‐specific immunotherapy mRNA‐4359 is a lipid nanoparticle–encapsulated mRNA‐based immunotherapy that encodes for the immunogenic indoleamine 2,3‐dioxygenase (IDO) and programmed death‐ligand 1 (PD‐L1) antigens.
Stephen A. Greene, Madhav Channavazzala, Bhairav Paleja, Harshbir Singh Sandhu, Rukmini Kumar, Husain Attarwala, Linh Van, Min Liang   +7 more
wiley   +1 more source

TNF Inhibitor‐Induced Sarcoidosis‐Like Lesions in Inflammatory Bowel Disease

United European Gastroenterology Journal, Volume 14, Issue 1, February 2026.
ABSTRACT Background While tumor necrosis factor (TNF) inhibitors can induce paradoxical reactions, sarcoidosis‐like disease has hardly been reported so far. This study aimed to describe the epidemiological, diagnostic and therapeutic features of TNF inhibitor‐induced sarcoidosis‐like lesions in patients with inflammatory bowel disease.
Zlata Chkolnaia, Benedicte Lebrun‐Vignes, Aurelien Amiot, Mathieu Uzzan, Nicolas Richard, Maeva Charkaoui, Guillaume Le Cosquer, Carmen Stefanescu, Melanie Serrero, Laurianne Plastaras, Sophie Vieujean, David Laharie, Philippe Seksik   +12 more
wiley   +1 more source

Clinical Characteristics, Molecular Diagnosis, and Drug Resistance Profiles of Nontuberculous Mycobacteria Infections: A Retrospective Analysis Using PCR Melting Curve Technology

Clinical and Translational Science, Volume 19, Issue 2, February 2026.
ABSTRACT Nontuberculous mycobacteria (NTM) are emerging global pathogens. This study aimed to analyze the clinical features, species distribution, and drug resistance profiles of NTM infections in a northern Chinese hospital. A retrospective cohort study included 1769 patients with suspected mycobacterial infection from August 2023 to July 2025.
Kedi Wang, Dongjiang Xu, Yan Gao, Wen Zhao, Kaihui Ma   +4 more
wiley   +1 more source

Comorbidities in People With Intellectual Disability With and Without Schizophrenia and Schizophrenia Without Intellectual Disability: A Swedish Register Study (IDcare)

Journal of Intellectual Disability Research, Volume 70, Issue 2, Page 206-217, February 2026.
ABSTRACT Background Intellectual disability (ID) and schizophrenia are known to separately carry a high risk of comorbidity of mental health and physical conditions. However, the prevalence and risk of comorbidities among people diagnosed with concurrent ID and schizophrenia have to date not been studied.
Trine Lise Bakken, Anna Axmon, Magnus Sandberg   +2 more
wiley   +1 more source

Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes

Advanced Functional Materials, Volume 36, Issue 1, 2 January 2026.
Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth, Neal I. Callaghan, Locke Davenport Huyer   +2 more
wiley   +1 more source

A Case of Lung Adenocarcinoma With Concurrent EGFR Mutation and ALK Fusion Combined With Literature Review

Clinical Case Reports, Volume 14, Issue 1, January 2026.
ABSTRACT This case underscores the critical importance of retesting for resistant mechanisms, such as EML4‐ALK fusion, in patients with EGFR‐mutant lung adenocarcinoma who experience rapid progression on EGFR‐tyrosine kinase inhibitor (TKI) therapy. Early identification of such co‐alterations and an immediate switch to alectinib can lead to rapid and ...
Yuzhu Chen, Fei Qi, Yixin Zeng, Jingwen Tan, Mingming Hu, Hongmei Zhang, Tongmei Zhang   +6 more
wiley   +1 more source

Beyond Raynaud's: Atypical Peripheral Vascular Manifestations in a Case of CREST Syndrome

Clinical Case Reports, Volume 14, Issue 1, January 2026.
ABSTRACT Peripheral vascular disease (PVD) is a rare but severe symptom of CREST syndrome, which itself is a limited cutaneous sclerosis. Even though Raynaud's phenomenon is the gold standard of CREST, the development of critical limb ischemia and self‐amputation is rare.
Sakshi Kumari, Fathimathul Henna, Umama Alam, Fazia Khattak, Kamil Ahmad Kamil   +4 more
wiley   +1 more source

Tuberculosis‐Associated Paradoxical Immune Reconstitution Inflammatory Syndrome in an HIV‐Negative Patient Presenting With a Recurrent Pleural Effusion Managed With Prednisolone: A Case Report

Clinical Case Reports, Volume 14, Issue 1, January 2026.
Chest CT scan 1 month after starting TB treatment demonstarting left side massive pleural effusion. ABSTRACT Non‐HIV‐infected people with pulmonary tuberculosis can develop paradoxical worsening of lung conditions, including massive pleural effusion, which at times requires multiple drainage. This paradoxical immune reconstitution inflammatory syndrome
Selam Bogale Gissa, Alemayehu Girma Gemechu, Selamawit Tilahun   +2 more
wiley   +1 more source