Results 121 to 130 of about 1,198,187 (379)
Histone Deacetylase 6 (HDAC6) in Ciliopathies: Emerging Insights and Therapeutic Implications
Advanced Science, EarlyView.HDAC6 regulates primary cilia, crucial for cellular signalling and environmental responses. Dysregulation of HDAC6 contributes to ciliopathies, affecting multiple organs. This review examines HDAC6's role in ciliogenesis, its interaction with signaling molecules, and its potential as a therapeutic target.
Zhiyi Wang +5 more
wiley +1 more source
Cancer Communications, Volume 42, Issue 12, Page 1314-1330, December 2022., 2022 Abstract Background Treatment options for Chinese patients with locally advanced or metastatic squamous‐cell non‐small‐cell lung cancer (sqNSCLC) after failure of first‐line chemotherapy are limited. This study (ORIENT‐3) aimed to evaluate the efficacy and safety of sintilimab versus docetaxel as second‐line treatment in patients with locally advanced ...
Yuankai Shi +45 more
wiley +1 more source
Туберкулез и болезни лёгких, 2016 The article describes the investigation of psychological and emotional state of pulmonary tuberculosis patients belonging to various categories having in-patient treatment.
G. V. Baranova +5 more
doaj
A Data Mining Approach to the Diagnosis of Tuberculosis by Cascading Clustering and Classification [PDF]
Journal of computing, volume 3, issue 4,April 2011, ISSN 2151-9617, 2011 In this paper, a methodology for the automated detection and classification of Tuberculosis(TB) is presented. Tuberculosis is a disease caused by mycobacterium which spreads through the air and attacks low immune bodies easily. Our methodology is based on clustering and classification that classifies TB into two categories, Pulmonary Tuberculosis(PTB ...
arxiv
Advanced Science, EarlyView.Large‐scale studies indicate a strong relationship between the gut microbiome, type 2 diabetes mellitus (T2DM), and atherosclerotic cardiovascular disease (ASCVD). Here, a higher abundance of the type III secretion system (T3SS) virulence factors of Enterobacteriaceae/Escherichia‐Shigella in patients with T2DM‐related‐ASCVD, which correlates with their
Yao‐Yuan Zhang +15 more
wiley +1 more source
Interference of Mycobacterium tuberculosis with macrophage responses [PDF]
, 2009 Tuberculosis, caused by Mycobacterium tuberculosis, has become an important health and economic burden, with more than four thousand people succumbing to the disease every day.
Jayachandran, R. +3 more
core
Point-of-care C-reactive protein-based tuberculosis screening for people living with HIV: a diagnostic accuracy study. [PDF]
, 2017 BackgroundSymptom-based screening for tuberculosis is recommended for all people living with HIV. This recommendation results in unnecessary Xpert MTB/RIF testing in many individuals living in tuberculosis-endemic areas and thus poor implementation of ...
Andama, Alfred O +12 more
core +1 more source
Structural and Biochemical Characterization of a Widespread Enterobacterial Peroxidase Encapsulin
Advanced Science, EarlyView.Encapsulins are self‐assembling bacterial protein compartments loaded with cargo enzymes. The most abundant encapsulin cargo class are Dye‐decolorizing Peroxidases (DyPs). In this study, we structurally and biochemically characterize a DyP encapsulin found in many enterobacteria.
Natalia C. Ubilla‐Rodriguez +2 more
wiley +1 more source
Туберкулез и болезни лёгких, 2017 Goal of study: to define species of non-tuberculosis mycobacteria, isolated from the respiratory tract of the patients from various Russian regions using DNA strips for identification of non-tuberculous mycobacteria.Materials and methods.
T. G. Smirnovа +5 more
doaj +1 more source