Results 161 to 170 of about 1,143,884 (302)

Accuracy and clinical utility of near-point-of-care blood tests for predicting incident tuberculosis in exposed contacts in high burden settings: a multi-country observational cohort study [PDF]

Res Sq
Abdulgader S, Chiwaya A, Banuls M, Ssengooba W, Nguenha D, Sserubiri J, Manjate P, Bazima C, Leukes V, Penn-Nicholson A, Katamba A, Joloba M, García-Basteiro A, Theron G, Cobelens F.   +14 more
europepmc   +2 more sources

Artificial intelligence for personalized multiple micronutrient supplementation in maternal health

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Maternal undernutrition and micronutrient deficiencies remain pervasive, contributing to adverse pregnancy outcomes and long‐term health risks for mothers and offspring. Multiple micronutrient supplementation (MMS) during pregnancy has demonstrated benefits, including reduced risks of low birth weight, small‐for‐gestational‐age births, and ...
Gabriel Davis Jones, Aris T. Papageorghiou, Hassan Shehata, Hema Divakar, Eline M. Van der Beek, Vyta Senikas, Justin C. Konje, Anne‐Beatrice Kihara, Moshe Hod, on behalf of the FIGO Committee on Women's Health and Technology   +9 more
wiley   +1 more source

Primary Testicular Tuberculosis Presenting as a Testicular Tumor: A Case Report. [PDF]

Clin Med Insights Case Rep
Sadeghzadeh S, Eslami M, Panahi Z, Danaei Mehrabad S.   +3 more
europepmc   +1 more source

Substrate Characterization of Mycobacterial Kinase PknG Revealing PknG‐KARS‐MAPK Phosphorylation Signaling Axis in Host

iMetaMed, EarlyView.
This study employed multi‐omics approaches to investigate the regulatory mechanism of Mycobacterium PknG on host cell processes. We found that host lysine‐tRNA ligase (KARS) is a potential substrate of PknG; and PknG can regulate the immune response by catalyzing the phosphorylation of KARS at T592 and T595 sites, affecting the phosphorylation level in
Nana Tian, Shuyu Xie, Yanqing Tang, Junjie Liang, Wenhan Zhu, Tianqi Liu, Yewen Sun, Yang Yang, Luoxi Zhang, Danfeng Wang, Chuyao Lin, Jinyu Jia, Minjia Tan, Jun‐Yu Xu   +13 more
wiley   +1 more source

Inuit experiences of and expertise on the 21st-century tuberculosis epidemic in Nunavik, Quebec: a qualitative community-based participatory study. [PDF]

CMAJ
Geboe B, Sandy G, Tooktoo D, Tukalak S, Law S, White-Dupuis S, Nappaaluk Q, Aliqu N, Quananack E, Emudluk M, Watt L, Mangiok P, Dunn-Suen A, Yaaka M, MacDonald NI, Khan FA.   +15 more
europepmc   +1 more source

A large‐scale single‐cell transcriptomic atlas indicates the immune panorama of influenza A infection

iMeta, EarlyView.
The study presents a large‐scale single‐cell transcriptomic atlas profiling over 612,010 peripheral immune cells from 97 individuals to decode the heterogeneity of influenza infection. These findings indicate a fundamental immune dichotomy determining clinical trajectories: a protective, monocyte‐centric antiviral state in mild disease versus a ...
Yi Wang, Shuzi Liu, Laurence Don Wai Luu, Yongzhi Zhai, Chenliang Zhu, Zhaomin Feng, Yao Tan, Linglong Wan, Jie Wang, Juan Zhou, Jing Wang, Lixin Xie, Quanyi Wang, Fei Xie   +13 more
wiley   +1 more source

Miliary tuberculosis with bilateral adrenal involvementand adrenal insufficiency. [PDF]

Rev Soc Bras Med Trop
Yeşilyurt M, Karaman A.
europepmc   +1 more source

Integrating Single‐Cell and Spatial Transcriptomes in HGSOC to Decipher the Metastasis‐Associated Biomarkers

iNew Medicine, EarlyView.
ABSTRACT High‐grade serous ovarian cancer (HGSOC) is the most common and lethal histological subtype of ovarian cancer. This study aimed to identify peritoneal metastasis‐associated biomarkers of HGSOC to provide directions for subsequent treatment. Transcriptome data were extracted from the GEO database and literature. Differential expression analysis,
Jing Zhu, Zhicheng Yu, Yang Zhang, Hui Hong, Xiaoli Wang, Shan Jiang, Ying Zhou, Cheng Peng, Hongbo Chen   +8 more
wiley   +1 more source

Spatiotemporal patterns of tuberculosis in urban slums and urban-rural transition zones: evidence from Tétouan, Morocco, 2019-2023. [PDF]

PLOS Glob Public Health
Ez-Zari A, Herrador Z, Farouk L, Mezzoug N, Boulaich A, Bouti K, Mennane Z, Elmtili N.   +7 more
europepmc   +1 more source

Interpretable machine learning enables early and accurate detection of drug‐induced liver injury: A multicenter study with real‐world clinical translation

Interdisciplinary Medicine, EarlyView.
This study develops an interpretable gradient‐boosting model that accurately identifies drug‐induced liver injury (DILI) using routine laboratory data. The model explains key clinical features through SHapley Additive exPlanations analysis and detects DILI earlier than expert evaluation, offering a transparent and practical tool for precision ...
Jingyi Ling, Shian Zhang, Jun Lin, Zhengju Xu, Runcheng Xu, Qian Lv, Kaixiang Zhang, Sheng Liu, Jie Guo, Cheng Hua, Yin Jia, Xiaoyu Xu, Kun Qian, Shanrong Liu   +13 more
wiley   +1 more source