Results 201 to 210 of about 790,262 (299)

Cytotoxic and Genotoxic Effects in Buccal Cells of Sandstone Quarry Workers

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT Mineral extraction poses significant occupational health risks, particularly from respirable crystalline silica exposure. Sandstone quarrying generates substantial dust, yet evidence of its genotoxic effects remains limited. This study investigated cytogenotoxic damage in sandstone quarry workers from southern Brazil using the buccal ...
Ana Carolina de Quadros Duarte   +6 more
wiley   +1 more source

Development and evaluation of a multiplex PCR for simultaneous detection of Mycobacterium tuberculosis complex, Mycobacterium avium complex, and Burkholderia pseudomallei in clinical specimens. [PDF]

open access: yesPLoS Negl Trop Dis
Binmaeil H   +9 more
europepmc   +1 more source

Performance Evaluation of the VISITECT CD4 Lateral Flow Point‐Of‐Care Assay for Identifying Advanced HIV Disease

open access: yesJournal of Clinical Laboratory Analysis, EarlyView.
The VISITECT CD4 lateral flow assay (LFA) was evaluated for identifying advanced HIV disease (CD4 ≤ 200 cells/μL) during routine programmatic implementation in Argentina. The assay showed 100% sensitivity, while specificity improved after observer training, reflecting reduced reader‐dependent variability.
Mariana Andreani   +7 more
wiley   +1 more source

Low‐Concentration Enhancement Effect: Enabling Sensitive Detection of EML4‐ALK Variants via Multiplex RT‐MIRA

open access: yesJournal of Clinical Laboratory Analysis, EarlyView.
This study developed an optimized multiplex RT‐MIRA assay for the simultaneous detection of EML4‐ALK variants, achieving single‐copy sensitivity. Unexpectedly, during the development of the reaction system, we discovered a “low‐concentration enhancement effect,” where reducing primer or probe concentrations within a specific range markedly improved ...
Xiao‐Dong Ren   +10 more
wiley   +1 more source

Association of IFN‐γ +874 T/A Polymorphism With COVID‐19 Susceptibility, Severity, and Inflammatory Response: A Case–Control Study From Southern Iran

open access: yesJournal of Clinical Laboratory Analysis, EarlyView.
Graphical abstract illustrating the association between IFN‐γ +874 T/A polymorphism and COVID‐19 outcomes. TA and AA genotypes are linked to increased susceptibility, higher inflammatory markers (notably IL‐6), greater disease severity, and longer hospitalization.
Nasir Arefinia   +4 more
wiley   +1 more source

Do Black and White Americans Differ in Willingness to Engage in Traditional, Alternative, and Religious Treatment Modalities for Depression?: A Hypothetical Vignette Study

open access: yesJournal of Clinical Psychology, EarlyView.
ABSTRACT Black Americans have lower engagement in traditional mental health treatment compared to White Americans. However, complementary and alternative medicine is widely used, can be integrated into traditional treatment, and may have fewer barriers associated with it than traditional treatment.
Alexis McGhee‐Dinvaut   +2 more
wiley   +1 more source

Production of recombinant human granulocyte‐macrophage colony‐stimulating factor in thermoinducible E. coli: Tuning inclusion body architecture and protein yield via dissolved oxygen control

open access: yesJournal of Chemical Technology &Biotechnology, EarlyView.
Abstract BACKGROUND Recombinant protein expression in Escherichia coli frequently results in the formation of inclusion bodies (IBs), which provide high protein accumulation but often require additional steps to recover functional protein. Although culture conditions strongly influence IB physicochemical and structural characteristics, the impact of ...
Ximena Gómez‐Gil   +7 more
wiley   +1 more source

Integrating anaerobic and photochemical processes: UV–vis‐driven post‐treatment for micropollutant abatement and toxicity control in UASB secondary effluent

open access: yesJournal of Chemical Technology &Biotechnology, EarlyView.
Abstract BACKGROUND Upflow anaerobic sludge blanket (UASB) reactors are widely used in low‐ and middle‐income countries, but secondary effluents may still contain organic micropollutants and residual toxicity. This study evaluated UV–Vis photolysis and UV/H2O2 as post‐treatment options for UASB secondary effluent (SE), integrating micropollutant ...
Fernando Rodrigues‐Silva   +10 more
wiley   +1 more source

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