Results 171 to 180 of about 358,265 (351)

Primary Hepatic Neuroendocrine Tumor in a Patient With Tuberous Sclerosis

Annals of Internal Medicine: Clinical Cases
Tuberous sclerosis is a rare multisystemic disease with common benign manifestations. However, recent research suggests a rare association with malignant tumors.
Lindsey Farmer, Julie Rowe
doaj   +1 more source

Motives and predictors of modified Atkins diet discontinuation as treatment of adults with drug‐resistant epilepsy

Epilepsia, EarlyView.
Abstract Objective This study was undertaken to explore the motives and predictors of modified Atkins diet (MAD) discontinuation as a treatment of adults with drug‐resistant epilepsy (DRE). Methods A single‐center observational longitudinal study was made of a cohort of patients treated with MAD during the first 6 years at a multidisciplinary ...
Raquel Samões, Ana Cavalheiro, Maria Manuel Tavares, Catarina Teixeira, Bárbara Leal, João Chaves, Sara Cavaco   +6 more
wiley   +1 more source

Supplementary Figures 1-5 from Tuberous Sclerosis Complex 1: An Epithelial Tumor Suppressor Essential to Prevent Spontaneous Prostate Cancer in Aged Mice

, 2023
Raleigh D. Kladney, Robert D. Cardiff, David J. Kwiatkowski, Gary G. Chiang, Jason D. Weber, Jeffrey M. Arbeit, Zhi Hong Lu   +6 more
openalex   +2 more sources

Bexicaserin for the treatment of seizures in developmental and epileptic encephalopathies: A phase 1b/2a trial (PACIFIC)

Epilepsia, EarlyView.
Abstract Objective This randomized, double‐blind, phase 1b/2a clinical trial was designed to evaluate the safety, tolerability, and efficacy of oral bexicaserin versus placebo for the treatment of seizures in adolescents and adults with developmental and epileptic encephalopathies (DEEs).
Dennis J. Dlugos, Ingrid E. Scheffer, Jacqueline A. French, David G. Vossler, Chad Orevillo, Shikha Polega, Randall Kaye, and the LP352‐201 Study Investigators, Kore Liow, Ena Zhu, Jennifer Waldron, Hayley Groubert, Alexis Anderson, Pavel Klein, Salman Hashmi, Shicong Ye, Anita Farhi, David Vossler, Dione M. Froman, Shannon L. Hoffman‐Huffaker, Ki Hyeong Lee, AnnaLyn Dallas, Amir Arain, Laura Beeler, Michael Macken, Irena Bellinski, Elizabeth Cunningham, James Renfroe, Shezsay Colbert, Robert Hogan, Patty Schaefer, Susan Shaw, Sheetal Desai, Ahmed Sadek, Haile Robertson, Kamil Detyniecki, Anabela Cieslicki, Ruben Kuzniecky, Sarah Goodman, Selim Benbadis, Marina Azevedo, Sami Aboumatar, Julie Biel, Nilika Singhal, Emerald Wan, Evan Fertig, Hannah Hart, Debopam Samanta, Sarah Hankins, Steven Wolf, Patricia Pena, Robert Nahouraii, M. J. Mari, David Burdette, Stephanie Mueller, Karen Keough, Victoria Henderson, Talitha Durgin, Terence O’Brien, Rafael Smith, Jack Germaine, Kate Riney, Lori Anthony, David Reutens, Kimberley Irwin, Michael Fahey, Melissa Batt, Stephanie Kaladis, Kasthoori Jeyachanthiran, Ingrid Scheffer, Rebecca Wharrie, Greesha Zacharia, Brittany Walsh, Heather Robinson, Sharon Ganter   +74 more
wiley   +1 more source

Double‐chambered left ventricle in a pediatric patient with tuberous sclerosis complex: A case report

Pediatric Investigation, EarlyView.
Haoxuan Li, Yufei Xie, Qun Wu, Xiaomin Duan, Fangyun Wang, Xin Zhang, Jing Wang   +6 more
wiley   +1 more source

EEG functional connectivity as a marker of evolution from infantile epileptic spasms syndrome to Lennox–Gastaut syndrome

Epilepsia, EarlyView.
Abstract Objective Timely diagnosis and effective treatment of Lennox–Gastaut syndrome (LGS) improve prognosis and lower health care costs, but the transition from infantile epileptic spasms syndrome (IESS) to LGS is highly variable and insidious. Objective biomarkers are needed to monitor this progression and guide clinical decision‐making. Methods We
Blanca Romero Milà, Virginia B. Liu, Rachel J. Smith, Derek K. Hu, Natalie A. Benneian, Shaun A. Hussain, Maija Steenari, Donald Phillips, David Adams, Clare Skora, Beth A. Lopour, Daniel W. Shrey   +11 more
wiley   +1 more source

Mutational spectrum of the TSC1 gene in a cohort of 225 tuberous sclerosis complex patients: no evidence for genotype-phenotype correlation [PDF]

, 1999
Marjon van Slegtenhorst, Senno Verhoef, A.M.P. Tempelaars, Lida Bakker, Qi Wang, Marja W. Wessels, Remco Bakker, Mark Nellist, Dick Lindhout, Dicky Halley, Ans van den Ouweland   +10 more
openalex   +1 more source

Pediatric Investigation Plans for seizure and epilepsy treatments: An analysis since the implementation of the European Pediatric Regulation in 2006

Epilepsia, EarlyView.
Abstract Objective A Pediatric Investigation Plan (PIP) implemented under the European Pediatric Regulation (EC No. 1901/2006) aims to ensure early and systematic evaluation of medicines for children. We analyze PIPs for antiseizure medications (ASMs) submitted to the European Medicines Agency (EMA) since 2006, characterizing their content, focusing on
Valeria Agostini, Stéphane Auvin
wiley   +1 more source

Tuberous Sclerosis

International Journal of Clinical Practice, 1963
I A, SALEEM, N H, WADIA, W D, SULAKHE
openaire   +2 more sources

Scalp high‐frequency activity differentiates neonates with seizures from healthy neonates and indicates postneonatal epilepsy risk

Epilepsia, EarlyView.
Abstract Objective This study investigated whether scalp high‐frequency activity (HFA) rates in neonates with seizures predict postneonatal epilepsy (PNE). It also assessed whether HFA rates differentiate neonates with seizures from healthy neonates and whether they vary by seizure etiology, therapeutic hypothermia, and electroencephalographic (EEG ...
Panagiota Karatza, Dorottya Cserpan, Santo Pietro Lo Biundo, Andrea Rüegger, Francesco Pisani, Johannes Sarnthein, Georgia Ramantani   +6 more
wiley   +1 more source