Results 201 to 210 of about 358,265 (351)

Tuberous sclerosis

, 2010
Tom Foster
openalex   +1 more source

An LC–MS/MS Method for the Quantitation of Metabolites M9, M12, and M20 of Bexicaserin in Human Cerebrospinal Fluid

Biomedical Chromatography, Volume 40, Issue 2, February 2026.
ABSTRACT The investigational molecule bexicaserin is a highly selective 5‐HT2C superagonist currently in Phase 3 clinical studies for the treatment of seizures associated with developmental and epileptic encephalopathies (DEEs). To facilitate its clinical development, a simple LC–MS/MS method was developed and validated for the quantitative estimation ...
Raja Reddy Kallem, Rosa Chan, Maisy Yeager, Katie Neal, Katharine Fletcher, Nuggehally R. Srinivas   +5 more
wiley   +1 more source

Tuberous Sclerosis: A Patient who presented with Fits

Journal of Rawalpindi Medical College, 2019
Tuberous sclerosis is an autosomal dominant genetic disease that causes benign lesions in various organs such as the kidneys, heart, liver, eyes, lungs, and skin.1 The pathogenesis of this disease involves mutation of either gene TSC1 or gene TSC2, that ...
Noor Fatima, Madeeha Nazar, Muhammad Hamza, Sehrish Iqbal, Nida Anjum, Muhammad Khurram, Faramarz Khan   +6 more
doaj  

Presentation and Outcomes of CNS Tumors Associated With Phakomatoses Syndromes From a Specialized Neuro‐Oncology Practice in India

Cancer Medicine, Volume 15, Issue 2, February 2026.
Encouraging survival is achieved in phakomatosis syndromes with conventional multimodality treatment (Surgery, RT, chemotherapy). There is an urgent need for easily administered systemic therapies which improve both quality and quantity of life. ABSTRACT Purpose Phakomatoses‐associated primary central nervous system (CNS) tumors are therapeutically ...
Anuradha Krishnan, Yamini Baviskar, Abhishek Chatterjee, Archya Dasgupta, Sridhar Epari, Arpita Sahu, Girish Chinnaswamy, Nandini Menon, Aliasgar Moiyadi, Tejpal Gupta, Jayant Sastri‐Goda   +10 more
wiley   +1 more source

Metformin‐Mediated Glycaemic Regulation as a Potential Strategy for Breast Cancer Prevention

Cancer Medicine, Volume 15, Issue 2, February 2026.
Metformin (MET), a common antihyperglycemic drug, shows promising anti‐cancer effects in breast cancer (BC). It activates adenosine monophosphate‐activated protein kinase (AMPK), regulating cellular energy and inducing cell cycle arrest, anti‐proliferation, and microenvironment alterations.
Ambulugala Gamage Rajika Greshamali Jinadasa, N. D. Amal Wageesha, Sameera R. Samarakoon, Sagarika Ekanayake, H. M. Kasuni Akalanka   +4 more
wiley   +1 more source

A case of tuberous sclerosis presenting with dysrhythmia in the first day of life

The Turkish Journal of Pediatrics, 2004
Cardiac rhabdomyoma (CR) is the most common primary cardiac tumor in childhood. Although CRs are asymptomatic in many cases, they may cause arrhythmia, heart failure and fetal hydrops.
Figen Akalin, Gökhan Baysoy, Birsen Oztürk, Yalim Yalçin, Gazanfer Ekici, Yüksel Yilmaz   +5 more
doaj  

Therapeutic Targeting of the Secreted Lysophospholipase D Autotaxin Suppresses Tuberous Sclerosis Complex-Associated Tumorigenesis

, 2020
You Feng, William J. Mischler, Ashish C. Gurung, Taylor R. Kavanagh, Grigoriy Androsov, Peter M. Sadow, Zachary T. Herbert, Carmen Priolo   +7 more
openalex   +2 more sources

Engineering Immortalized Bovine Granulosa Cells Using a Triple‐Gene Approach: Mutant CDK4, Cyclin D1, and TERT

Cell Biology International, Volume 50, Issue 2, February 2026.
ABSTRACT Advancing reproductive technologies in livestock is essential to improve both productivity and genetic potential of cattle. Despite this importance, application of reproductive biotechnologies in cattle breeding remains limited. Bovine granulosa cells (bGCs), which are key components of the ovarian follicle, are critical in female reproduction
Lanlan Bai, Minami Takahashi, Jin Kobayashi, Takahiro Eitsuka, Himari Matsusaka, Taku Ozaki, Eriko Sugano, Hiroshi Tomita, Yuan Xu, Kazuhiro Kawamura, Kiyotaka Nakagawa, Tohru Kiyono, Tomokazu Fukuda   +12 more
wiley   +1 more source

Onychomatricoma with Tuberous Sclerosis: A Novel Association? [PDF]

Indian Dermatol Online J
Grover C, Gaurav V, Sharma S.
europepmc   +1 more source

Primary Hyperparathyroidism With Brown Tumor—A Case Mistaken as Non‐Ossifying Fibroma Resolved by Biochemical and Radiological Correlation

Clinical Case Reports, Volume 14, Issue 2, February 2026.
ABSTRACT Primary hyperparathyroidism (PHPT) is uncommon in the pediatric population and rarely presents with overt skeletal complications such as brown tumors. This case study describes a 16‐year‐old female who initially presented with abdominal pain and was subsequently found to have severe hypercalcemia (serum calcium 16.4 mg/dL) and markedly ...
Dosti Regmi, Uma Bhatta, Madhur Bhattarai, Saurav Jha, Akriti Baral   +4 more
wiley   +1 more source