Results 171 to 180 of about 29,392 (272)
Severe Renal Phenotype Across A Multigenerational Tuberous Sclerosis Complex (TSC) Family. [PDF]
Tuller E +3 more
europepmc +1 more source
ABSTRACT Background The role of bone grafting in subtalar joint arthrodesis (SJA) remains controversial. This study aimed to compare clinical and radiographic outcomes of SJA performed with and without bone graft and to evaluate the influence of different graft types on fusion and functional results.
Giovan Giuseppe Mazzella +11 more
wiley +1 more source
Abstract Objective To evaluate neurodevelopment at 24 months in infants surgically treated for esophageal atresia (EA), using the ages and stages questionnaire (ASQ), and identify perinatal and early‐life factors associated with developmental delay. Methods Infants with EA were prospectively enrolled in a structured multidisciplinary follow‐up program.
Julia Tagmouti +8 more
wiley +1 more source
Shagreen Patch in Tuberous Sclerosis Complex at High-Frequency Ultrasound. [PDF]
Tagliati C, Wortsman X.
europepmc +1 more source
A 3D bioprinted breast cancer model was created to more accurately reproduce in vivo tumor characteristics compared to conventional 2D cultures. Distinct cell adhesion patterns, reduced mTOR signaling, and altered drug responses were observed under 3D conditions.
Dorottya Moldvai +10 more
wiley +1 more source
The Dual Role of Autophagy in Cancer: Mechanisms and Therapeutic Strategies
Autophagy is a conserved cellular process degrading dysfunctional organelles and protein aggregates to maintain cell homeostasis, and it exhibits context‐dependent duality in cancer. Autophagy functions as a critical tumor‐suppressive mechanism by preventing DNA damage and mutation during tumor initiation.
Xiang‐Zheng Gao +4 more
wiley +1 more source
A case report of transcatheter arterial embolization for extra-renal retroperitoneal angiomyolipoma associated with tuberous sclerosis complex. [PDF]
Iwamura S +9 more
europepmc +1 more source
Oxidative Stress in the Tumor Immune Microenvironment: Mechanisms and Therapeutic Perspectives
Oxidative stress is involved in several key processes in cancer, including redox regulation, DNA damage, post‐translational modifications, transcriptional regulation, epigenetic modifications, metabolic reprogramming, cell death, and immune modulation. These mechanisms collectively influence tumor progression, immune evasion, and therapeutic responses,
Zhen Wang +14 more
wiley +1 more source
Multifocal micronodular pneumocyte hyperplasia in the absence of tuberous sclerosis complex: A case report. [PDF]
Chikasue T +9 more
europepmc +1 more source
Targeting EZH2 in Cancer: From Molecular Mechanisms to Clinical Translation
The abnormal overexpression or gain‐of‐function mutations of EZH2 play a significant role in cancer occurrence and progression, highlighting the importance and potential of EZH2 as a cancer biomarker. Therefore, screening for effective and safe small‐molecule inhibitors, degraders, and natural compounds targeting EZH2 through preclinical cancer models ...
Xi Zhong +4 more
wiley +1 more source

