Results 161 to 170 of about 29,889 (183)

A Blood‐Derived Factor Rescues ALS: Platelet Factor 4 Activates OPTN‐Dependent Autophagy to Clear SOD1 Aggregates Independently of PINK1

Advanced Science, Volume 13, Issue 58, 19 October 2026.
Systemic platelet factor 4 (PF4) is significantly depleted in amyotrophic lateral sclerosis (ALS). Peripheral PF4 replenishment restores central proteostasis by driving OPTN‐dependent, PINK1‐independent selective autophagy in motor neurons. This intervention effectively clears toxic SOD1 aggregates, blunts glial activation, and preserves neuromuscular ...
Qingjian Xie, Yanbo Zhu, Wenhua Jiang, Haobo Xie, Yaojia Li, Mengjie Hu, Kezheng Li, Huan Yu, Yixuan Pan, Chaoyi Jiang, Xueqin Song, Dongsheng Fan, Binbin Deng   +12 more
wiley   +1 more source

Biomimetic Scaffold‐Based 3D Models for Decoding Cancer Biology and Advancing Therapy

Advanced Science, Volume 13, Issue 58, 19 October 2026.
A timeline of the research history of 3D biomimetic scaffold materials and platforms. With advances in biomimetic materials and 3D scaffold technologies, their functional scope has expanded from mimicking basic physical and biochemical properties to increasingly replicating complex pathophysiological processes.
Haitao Zhao, Yuechen Han, Jie Li, Peng Luo, Lin Qi, Zhiwei Xia, Xiaosong Li, Quan Cheng, Chenshen Huang, Wantao Wu, Hao Zhang   +10 more
wiley   +1 more source

Immunonutritional Effects of Nucleotides and Olive Bioactive Extracts on Growth Performance and Survival of Pacific White Shrimp Upon Vibrio parahaemolyticus (AHPND) Challenge

Aquaculture, Fish and Fisheries, Volume 6, Issue 5, October 2026.
ABSTRACT The sustainable advancement of aquaculture can be supported using functional feed ingredients with immunomodulatory activity. These studies evaluated the immunonutritional effects of dietary nucleotides (NU) and an olive bioactive extract (OE) in Pacific white shrimp (PWS), Penaeus vannamei. A 56‑day growth trial (n = 1000 PWS; PL42‐43; 1.23 ± 
Sergi Segarra, José Carlos Quintela, Maxime Vallot, Thanh Chau, Phuc Hoang, Loc Tran   +5 more
wiley   +1 more source

Dynamic Obstacle Avoidance of Metamorphic Microrobots Using Concentric Sector Navigator

Advanced Intelligent Systems, Volume 8, Issue 10, October 2026.
Metamorphic magnetic microrobots are navigated using a concentric sector navigator for dynamic obstacle avoidance in both microroller and swarm states. After microroller transport, citrate‐triggered dissolution releases nanoparticles that reassemble into a controllable swarm.
Zhaowen Su, Zerui Li, Lijun Fang, Hoyeon Kim, U Kei Cheang   +4 more
wiley   +1 more source

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Implications of failure of alloy 718 (UNS N07718) tubing hanger in sour well

Engineering Failure Analysis, 2021
Janardhan Saithala, Amjad Kharusi, Talal Nabhani   +2 more
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A model for reliability assessment of sealing performance of the C-shaped metal sealing ring at the outlet of the subsea tubing hanger

Ocean Engineering, 2022
Jianchang Li, Www Jjj
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Umbilical-Less Tubing Hanger Installation Controls System

2021
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Non-orientating tubing hanger and tree

Sealing Technology, 2020
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Tubing hanger with a shiftable annulus seal

Sealing Technology, 2020
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High-Power ESP Tubing-Hanger Connector for Deepwater Downhole Applications

JPT, Journal of Petroleum Technology, 2014
Adam Wilson
exaly