Results 1 to 10 of about 122,654 (313)
Mitochondrial organization in the developing proximal tubule is controlled by LRRK2 [PDF]
Nature CommunicationsThe proximal tubule of the nephron performs energy-demanding functions such as resorption of water, amino acids and glucose. Formation of the energy-producing machinery is an essential step in proximal tubule epithelial cell differentiation, and this ...
Mohsina Khan +8 more
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Disease Modeling with Kidney Organoids
Micromachines, 2022 Kidney diseases often lack optimal treatments, causing millions of deaths each year. Thus, developing appropriate model systems to study human kidney disease is of utmost importance.
Sophie Karp +2 more
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Early renal structural changes and potential biomarkers in diabetic nephropathy
Frontiers in Physiology, 2022 Diabetic nephropathy is one of the most serious microvascular complications of diabetes mellitus, with increasing prevalence and mortality. Currently, renal function is assessed clinically using albumin excretion rate and glomerular filtration rate.
Hao Liu, Jianguo Feng, Liling Tang
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A novel quantitative measurement method for irregular tubules in breast carcinoma
Engineering Science and Technology, an International Journal, 2022 Tubule detection is very crucial and is one of the important criterions for tubule formation assessment in breast carcinoma. The output of tubule formation is essential to determine the grade of breast carcinoma based on the Nottingham Histological ...
Xiao Jian Tan +3 more
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Distal Convoluted Tubule [PDF]
Clinical Journal of the American Society of Nephrology, 2014 The distal convoluted tubule is the nephron segment that lies immediately downstream of the macula densa. Although short in length, the distal convoluted tubule plays a critical role in sodium, potassium, and divalent cation homeostasis. Recent genetic and physiologic studies have greatly expanded our understanding of how the distal convoluted tubule ...
Arohan R, Subramanya, David H, Ellison
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Cells, 2020 Tubular injury and fibrosis are associated with progressive kidney dysfunction in advanced glomerular disease. Glomerulotubular crosstalk is thought to contribute to tubular injury.
Jin Seok Jeon +9 more
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Renalase's expression and distribution in renal tissue and cells. [PDF]
PLoS ONE, 2012 To study renalase's expression and distribution in renal tissues and cells, renalase coded DNA vaccine was constructed, and anti-renalase monoclonal antibodies were produced using DNA immunization and hybridoma technique, followed by further ...
Feng Wang +8 more
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Materials Science and Engineering: C, 1997 Dispersion of tubules made of diacetylenic phospholipids (DC 8,9 PC), in aqueous colloidal dispersions of magnetic nanoparticles is studied as a function of the sign of particles surface charges. In every case the tubule-vesicle transition temperature is decreased by the presence of the magnetic nanoparticles. Electrophoresis experiments on the tubules
Letellier, Damien +4 more
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Impact of Diabetic Stress Conditions on Renal Cell Metabolome
Cells, 2019 Diabetic kidney disease is a major complication in diabetes mellitus, and the most common reason for end-stage renal disease. Patients suffering from diabetes mellitus encounter glomerular damage by basement membrane thickening, and develop albuminuria ...
Simon Lagies +9 more
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Cell Communication and Signaling, 2023 Background Without a viable cure, chronic kidney disease is a global health concern. Inflammatory damage in and around the renal tubules dictates disease severity and is contributed to by multiple cell types.
Elena Roger +8 more
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