Results 1 to 10 of about 286,999 (386)
Genetic screen in Drosophila muscle identifies autophagy-mediated T-tubule remodeling and a Rab2 role in autophagy. [PDF]
eLife, 2017 Transverse (T)-tubules make-up a specialized network of tubulated muscle cell membranes involved in excitation-contraction coupling for power of contraction. Little is known about how T-tubules maintain highly organized structures and contacts throughout
Fujita, Naonobu +10 more
core +3 more sources
Exosomal GAPDH from Proximal Tubule Cells Regulate ENaC Activity. [PDF]
PLoS ONE, 2016 Exosomes are nanometer-scale, cell-derived vesicles that contain various molecules including nucleic acids, proteins, and lipids. These vesicles can release their cargo into adjacent or distant cells and mediate intercellular communication and cellular ...
Kishore Kumar Jella +5 more
doaj +2 more sources
Distal Convoluted Tubule [PDF]
Clinical Journal of the American Society of Nephrology, 2014 The distal convoluted tubule is the nephron segment that lies immediately downstream of the macula densa. Although short in length, the distal convoluted tubule plays a critical role in sodium, potassium, and divalent cation homeostasis. Recent genetic and physiologic studies have greatly expanded our understanding of how the distal convoluted tubule ...
David H. Ellison +2 more
openaire +4 more sources
In vivo and in situ evaluation of innovative approaches in dentin hypersensitivity treatment [PDF]
BMC Oral HealthBackground Dentin hypersensitivity (DH) causes transient sharp pain from exposed dentinal tubules, adversely affecting oral health and quality of life.
Heba Abd El-Fattah Mohamed +3 more
doaj +2 more sources
SUBSTRUCTURE OF FLAGELLAR TUBULES [PDF]
The Journal of Cell Biology, 1966 David M. Phillips
openaire +4 more sources
miR-127 protects proximal tubule cells against ischemia/reperfusion : identification of Kinesin family member 3B as miR-127 target [PDF]
, 2012 Ischemia/reperfusion (I/R) is at the basis of renal transplantation and acute kidney injury. Molecular mechanisms underlying proximal tubule response to I/R will allow the identification of new therapeutic targets for both clinical settings.
Aguado-Fraile, Elia +9 more
core +26 more sources
Early renal structural changes and potential biomarkers in diabetic nephropathy
Frontiers in Physiology, 2022 Diabetic nephropathy is one of the most serious microvascular complications of diabetes mellitus, with increasing prevalence and mortality. Currently, renal function is assessed clinically using albumin excretion rate and glomerular filtration rate.
Hao Liu, Jianguo Feng, Liling Tang
doaj +1 more source
eLife, 2023 Ring-like structures made up of caveolae appear to drive the development of membrane invaginations called T-tubules which are important for muscle contraction.
Callum J Quinn, Katharine M Dibb
openaire +3 more sources
The Promise of Tubule Biomarkers in Kidney Disease: A Review.
American Journal of Kidney Diseases, 2021 For over 70 years, serum creatinine has remained the primary index for detection and monitoring of kidney disease. Tubulo-interstitial damage and fibrosis are highly prognostic for subsequent kidney failure in biopsy studies, yet this pathology is ...
J. Ix, M. Shlipak
semanticscholar +1 more source
Disease Modeling with Kidney Organoids
Micromachines, 2022 Kidney diseases often lack optimal treatments, causing millions of deaths each year. Thus, developing appropriate model systems to study human kidney disease is of utmost importance.
Sophie Karp +2 more
doaj +1 more source