Results 101 to 110 of about 109,157 (295)

Micropuncture study of hypertonic mannitol diuresis in the proximal and distal tubule of the dog kidney [PDF]

, 1969
J. F. Seely, John H. Dirks
openalex   +1 more source

A Novel Cultivation System for Germ Cell Proliferation and Sustaining Whole Testicular Niche

Advanced Science, EarlyView.
A hydrogel microneedle‐based system enables whole testicular cultivation, supporting spermatogonial proliferation and enhancing spermatogenesis in vitro. This ‘whole testicular spermatogonia pool’ (WTSP) significantly increases spermatid production and fertility potential in mice. This system also promotes spermatogonial expansion in human fetal testes,
Yu Xia, Xiaoxuan Zhang, Bohang Zhang, Minhui Lu, Qing Cheng, Li Liu, Lifang Shi, Yiqiang Cui, Dingdong Chen, Laihua Li, Xuejiang Guo, Jingtao Guo, Jiahao Sha, Yuanjin Zhao, Yan Yuan   +14 more
wiley   +1 more source

Distinct Bin/Amphiphysin/Rvs (BAR) family proteins may assemble on the same tubule to regulate membrane organization in vivo

Heliyon
Intracellular membrane tubules play a crucial role in diverse cellular processes, and their regulation is facilitated by Bin-Amphiphysin-Rvs (BAR) domain-containing proteins.
Bhagaban Mallik, Srikanth Pippadpally, Anjali Bisht, Sajad Bhat, Surabhi Mukherjee, Vimlesh Kumar   +5 more
doaj  

An inhibitory effect of furosemide on sodium reabsorption by the proximal tubule of the rat nephron [PDF]

, 1969
Barry M. Brenner, Robert I. Keimowitz, Fred S. Wright, Robert W. Berliner   +3 more
openalex   +1 more source

Podocyte RIPK3 Deletion Improves Diabetic Kidney Disease by Attenuating NF‐κB p65 Driven Inflammation

Advanced Science, EarlyView.
Prevention and treatment of diabetic kidney disease (DKD) have become a major global public health challenge. This study shed new light on the underlying pathogenic mechanisms of podocyte injury in DKD and highlights the therapeutic potential of mitigating podocyte injury through inhibition of the RIPK3/NF‐κB p65‐mediated inflammatory response as a ...
Lu'an Li, Jiaying Li, Ruizhao Li, Xingchen Zhao, Yuanhan Chen, Yating Cai, Yan Yang, Weiteng Wang, Siqi Zheng, Li Zhang, Xinling Liang   +10 more
wiley   +1 more source

YAP1 preserves tubular mitochondrial quality control to mitigate diabetic kidney disease

Redox Biology
Renal tubule cells act as a primary site of injury in diabetic kidney disease (DKD), with dysfunctional mitochondrial quality control (MQC) closely associated with progressive kidney dysfunction in this context. Our investigation delves into the observed
Siyang Ye, Meng Zhang, Xunhua Zheng, Suchun Li, Yuting Fan, Yiqin Wang, Huajing Peng, Sixiu Chen, Jiayi Yang, Li Tan, Manhuai Zhang, Peichen Xie, Xiaoyan Li, Ning Luo, Zhipeng Wang, Leigang Jin, Xiaoping Wu, Yong Pan, Jinjin Fan, Yi Zhou, Sydney C.W. Tang, Bin Li, Wei Chen   +22 more
doaj  

Potassium reabsorption in the proximal tubule of the dog nephron. [PDF]

, 1966
John F. Watson
openalex   +1 more source

Neutrophil–Endothelium Interaction Mediated by S100A9 Promotes Pulmonary Vascular Remodeling During Pulmonary Hypertension

Advanced Science, EarlyView.
This study investigates the critical mechanisms underlying pulmonary hypertension progression, with a focus on the novel role of neutrophil‐derived S100A9 in endothelial dysfunction‐mediated pulmonary vascular remodeling. By integrating human lung samples, multi‐omics analyses, animal models, and mechanistic in vitro studies, it is revealed that how ...
Yu Guo, Zhenqiang Gao, Ruoyang Zhang, Huanyu Long, Muzhi Zhang, Lin Liu, Zhe An, Yuezhe Shi, Ye Cui, Yufeng Jia, Lei Wang, Ying Sun, Jie Liu, Wei Wang   +13 more
wiley   +1 more source

Cysts arising in the renal tubules. A microdissection study. [PDF]

, 1965
Thelma J. Baxter
openalex   +1 more source

Multi‐Omics and ‐Organ Insights into Energy Metabolic Adaptations in Early Sepsis Onset

Advanced Science, EarlyView.
This study shows that patients at risk of sepsis have a distinct metabolite and lipid signature, including serine and aminoadipic acid, in their serum before clinical diagnosis. A mouse model of sepsis with a compatible serum signature reveals underlying metabolic changes, including mitochondrial adaptation, altered serine‐dependent purine metabolism ...
Lin‐Lin Xu, Zhengyuan Zhou, Sascha Schäuble, Wolfgang Vivas, Karen Dlubatz, Michael Bauer, Sebastian Weis, Mervyn Singer, Roman Lukaszewski, Gianni Panagiotou   +9 more
wiley   +1 more source