Results 21 to 30 of about 286,999 (386)
Phases and Transitions in Phantom Nematic Elastomer Membranes [PDF]
Motivated by recently discovered unusual properties of bulk nematic elastomers, we study a phase diagram of liquid-crystalline polymerized phantom membranes, focusing on in-plane nematic order.
D. R. Nelson+5 more
core +1 more source
Impact of Diabetic Stress Conditions on Renal Cell Metabolome
Diabetic kidney disease is a major complication in diabetes mellitus, and the most common reason for end-stage renal disease. Patients suffering from diabetes mellitus encounter glomerular damage by basement membrane thickening, and develop albuminuria ...
Simon Lagies+9 more
doaj +1 more source
Background Without a viable cure, chronic kidney disease is a global health concern. Inflammatory damage in and around the renal tubules dictates disease severity and is contributed to by multiple cell types.
Elena Roger+8 more
doaj +1 more source
The corticotropin-releasing factor-like diuretic hormone 44 (DH44) and kinin neuropeptides modulate desiccation and starvation tolerance in Drosophila melanogaster [PDF]
Malpighian tubules are critical organs for epithelial fluid transport and stress tolerance in insects, and are under neuroendocrine control by multiple neuropeptides secreted by identified neurons. Here, we demonstrate roles for CRF-like diuretic hormone
Cannell, Elizabeth+5 more
core +2 more sources
Kidney Injury Molecule-1 (KIM-1): a novel biomarker for human renal proximal tubule injury.
BACKGROUND Traditional blood and urine markers for the diagnosis of various renal diseases are insensitive and nonspecific. Kidney Injury Molecule-1 (KIM-1) is a type 1 transmembrane protein, with an immunoglobulin and mucin domain, whose expression is ...
W. Han+4 more
semanticscholar +1 more source
Generation of proximal tubule spheroids for nephrotoxicity assessment [PDF]
Background To date, nephrotoxicity in new drug development has been evaluated through two-dimensional culture of representative cell lines, such as HK-2 and human proximal tubule epithelial cells (hPTECs). Approximately 20% of new drugs that were safe in
Dae Hun Kim+3 more
doaj +1 more source
There is an alarming global increase in the incidence of end-stage kidney disease, for which early biomarkers and effective treatment options are lacking.
R. Chevalier
semanticscholar +1 more source
Transverse tubules (T-tubules) are orderly invaginations of the sarcolemma in mammalian cardiomyocytes. The integrity of T-tubule architecture is critical for cardiac excitation-contraction coupling function.
Biyi eChen+3 more
doaj +1 more source
Identification of Multiple Functional Receptors for Tyramine on an Insect Secretory Epithelium [PDF]
The biogenic amine tyramine (TA) regulates many aspects of invertebrate physiology and development. Although three TA receptor subtypes have been identified (TAR1-3), specific receptors have not been linked to physiological responses in native tissue. In
Blumenthal, Edward M, Zhang, Haiying
core +2 more sources
Equine Hoof Wall Deformation: Novel Aspects Revealed
The equine hoof wall has a unique hierarchical structure that allows it to survive high‐impact scenarios. Previous authors have explored the compressive, viscoelastic, and fracture control properties of the hoof wall and suggested that this complex ...
Benjamin S. Lazarus+5 more
doaj +1 more source