Results 21 to 30 of about 122,654 (313)
Longitudinal tracking of acute kidney injury reveals injury propagation along the nephron
Nature Communications, 2023 Acute kidney injury (AKI) is an important risk factor for chronic kidney disease (CKD), but the underlying mechanisms of failed tubule repair and AKI-CKD transition are incompletely understood.
Luca Bordoni +6 more
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Kidney & Blood Pressure Research, 2021 Introduction: The diameter and area of the proximal convoluted tubule (PCT) and the distal convoluted tubule (DCT) are of the main parameters analyzed in stereological studies of the kidney.
Marta Ortega-Martinez +5 more
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Recrystallization of tubules from natural lotus (Nelumbo nucifera) wax on a Au(111) surface
Beilstein Journal of Nanotechnology, 2011 We present here the first results on the self-assembly of tubules of natural wax from lotus leaves on a single crystal Au(111) surface. A comparison of the tubule growth on Au(111) to that on HOPG is discussed.
Sujit Kumar Dora, Klaus Wandelt
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A Deep Learning Approach for Classification of Dentinal Tubule Occlusions
Applied Artificial Intelligence, 2022 This study aimed to develop a novel deep learning model for reliable quantification of dentinal tubule occlusions instead of manual assessment techniques, and the performance of the model was compared to other methods in the literature. Ninety-six dentin
Anday Duru +3 more
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JACC: Basic to Translational Science, 2016 Cardiac myocytes from the mdx mouse, the mouse model of Duchenne muscular dystrophy, exhibit t-tubule disarray and increased calcium sparks, but a unifying molecular mechanism has not been elucidated.
Kurt W. Prins, MD, PhD +4 more
doaj +1 more source
Research Progress of Drug Delivery Systems Targeting the Kidneys
PharmaceuticalsChronic kidney disease (CKD) affects more than 10% of the global population, and its incidence is increasing, partially due to an increase in the prevalence of disease risk factors.
Li-Feng Huang +7 more
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Enhanced MCP-1 Release in Early Autosomal Dominant Polycystic Kidney Disease
Kidney International Reports, 2021 Introduction: Autosomal dominant polycystic kidney disease (ADPKD) causes kidney failure typically in adulthood, but the disease starts in utero. Copeptin, epidermal growth factor (EGF), and monocyte chemoattractant protein-1 (MCP-1) are associated with ...
Peter Janssens +16 more
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Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Micromachines, 2021 Kidney microphysiological systems (MPS) serve as potentially valuable preclinical instruments in probing mechanisms of renal clearance and osmoregulation. Current kidney MPS models target regions of the nephron, such as the glomerulus and proximal tubule
Stephanie Y. Zhang, Gretchen J. Mahler
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Molecular Oncology, EarlyView.The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source