Results 21 to 30 of about 109,157 (295)

Efficacy of remineralizing agents to occlude dentinal tubules in primary teeth subjected to dentin hypersensitivity in vitro: SEM study

open access: yesJournal of Family Medicine and Primary Care, 2020
Aim: Comparison of casein phosphopeptides (CPPs) and amorphous calcium phosphate (ACP), tricalcium phosphate, and hydroxyapatite on assessment of dentine tubule occlusion on primary enamel using scanning electron microscope (SEM).
Mebin George Mathew   +5 more
doaj   +1 more source

Cells sorted off hiPSC-derived kidney organoids coupled with immortalized cells reliably model the proximal tubule

open access: yesCommunications Biology, 2023
Of late, numerous microphysiological systems have been employed to model the renal proximal tubule. Yet there is lack of research on refining the functions of the proximal tubule epithelial layer—selective filtration and reabsorption.
Ramin Banan Sadeghian   +7 more
doaj   +1 more source

The role of renal proximal tubule transport in the regulation of blood pressure

open access: yesKidney Research and Clinical Practice, 2017
The electrogenic sodium/bicarbonate cotransporter 1 (NBCe1) on the basolateral side of the renal proximal tubule plays a pivotal role in systemic acid-base homeostasis.
Shoko Horita   +6 more
doaj   +1 more source

The Convoluted Tubules of the Nephron Must Be Considered Elliptical, and Not Circular, in Stereological Studies of the Kidney

open access: yesKidney & Blood Pressure Research, 2021
Introduction: The diameter and area of the proximal convoluted tubule (PCT) and the distal convoluted tubule (DCT) are of the main parameters analyzed in stereological studies of the kidney.
Marta Ortega-Martinez   +5 more
doaj   +1 more source

A Deep Learning Approach for Classification of Dentinal Tubule Occlusions

open access: yesApplied Artificial Intelligence, 2022
This study aimed to develop a novel deep learning model for reliable quantification of dentinal tubule occlusions instead of manual assessment techniques, and the performance of the model was compared to other methods in the literature. Ninety-six dentin
Anday Duru   +3 more
doaj   +1 more source

Microtubule-Mediated Misregulation of Junctophilin-2 Underlies T-Tubule Disruptions and Calcium Mishandling in mdx Mice

open access: yesJACC: Basic to Translational Science, 2016
Cardiac myocytes from the mdx mouse, the mouse model of Duchenne muscular dystrophy, exhibit t-tubule disarray and increased calcium sparks, but a unifying molecular mechanism has not been elucidated.
Kurt W. Prins, MD, PhD   +4 more
doaj   +1 more source

Recrystallization of tubules from natural lotus (Nelumbo nucifera) wax on a Au(111) surface

open access: yesBeilstein Journal of Nanotechnology, 2011
We present here the first results on the self-assembly of tubules of natural wax from lotus leaves on a single crystal Au(111) surface. A comparison of the tubule growth on Au(111) to that on HOPG is discussed.
Sujit Kumar Dora, Klaus Wandelt
doaj   +1 more source

Longitudinal tracking of acute kidney injury reveals injury propagation along the nephron

open access: yesNature Communications, 2023
Acute kidney injury (AKI) is an important risk factor for chronic kidney disease (CKD), but the underlying mechanisms of failed tubule repair and AKI-CKD transition are incompletely understood.
Luca Bordoni   +6 more
doaj   +1 more source

T‐tubule trouble

open access: yesThe Journal of Physiology, 2006
During the cardiac action potential, Ca2+ influx via L-type Ca2+ channels activates Ca2+ release channels (ryanodine receptors; RyRs) in adjacent sarcoplasmic reticulum (SR) membrane, causing Ca2+ release from the SR and thus contraction. There is increasing evidence that in ventricular myocytes the transverse (t-) tubules – invaginations of the ...
openaire   +4 more sources

Modelling Renal Filtration and Reabsorption Processes in a Human Glomerulus and Proximal Tubule Microphysiological System

open access: yesMicromachines, 2021
Kidney microphysiological systems (MPS) serve as potentially valuable preclinical instruments in probing mechanisms of renal clearance and osmoregulation. Current kidney MPS models target regions of the nephron, such as the glomerulus and proximal tubule
Stephanie Y. Zhang, Gretchen J. Mahler
doaj   +1 more source

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