Results 41 to 50 of about 109,157 (295)

Epcam, CD44, and CD49f distinguish sphere-forming human prostate basal cells from a subpopulation with predominant tubule initiation capability. [PDF]

PLoS ONE, 2012
BackgroundHuman prostate basal cells expressing alpha-6 integrin (CD49f(Hi)) and/or CD44 form prostaspheres in vitro. This functional trait is often correlated with stem/progenitor (S/P) activity, including the ability to self-renew and induce ...
Changyong Guo, Haibo Liu, Bao-Hui Zhang, Radu M Cadaneanu, Aqila M Mayle, Isla P Garraway   +5 more
doaj   +1 more source

The Drosophila Malpighian tubule as a model for mammalian tubule function

Current Opinion in Nephrology and Hypertension, 2019
Studies of the genetic model organism, Drosophila melanogaster, have unraveled molecular pathways relevant to human physiology and disease. The Malpighian tubule, the Drosophila renal epithelium, is described here, including tools available to study transport; conserved transporters, channels, and the signaling pathways regulating them; and fly models ...
openaire   +4 more sources

Microphysiological Glomerular Filtration Barriers: Current Insights, Innovations, and Future Applications

Advanced Biology, EarlyView.
The glomerular filtration barrier (GFB) is the first step of blood filtration by the kidneys. The concerning increase of kidney diseases makes the development of new models essential. In this context, microphysiological glomerular filtration barriers focus on closely reproducing the physiological architecture of the in vivo GFB: podocytes, glomerular ...
Manon Miran, Kieu Ngo, David Buob, Hanna Debiec, Pierre Ronco, Guillaume Perry   +5 more
wiley   +1 more source

Experimental Study on Flow Pattern Characteristics of CO2 during Flow Boiling Heat Transfer Process in a Horizontal Tubule

Zhileng xuebao, 2019
In this paper, theoretical analysis and visual experimental research are reported on the flow-state characteristics during the heat transfer of CO2 flow boiling in a horizontal tubule.
Zhang Liang, Liu Jianhua, Wu Qingqing, Jiang Linlin, Zhao Yue   +4 more
doaj  

Relationship among nephron number, cortical volume, and glomerular pressure in healthy kidney donors

Physiological Reports
Glomerular hypertension is a critical factor in kidney disease progression. Traditionally, nephron number (Nglom) was considered a determinant of glomerular hemodynamics, but emerging evidence suggests a more substantial impact of renal structural ...
Hiroki Nobayashi, Go Kanzaki, Takaya Sasaki, Rina Oba, Yusuke Okabayashi, Kotaro Haruhara, Kentaro Koike, Akimitsu Kobayashi, Izumi Yamamoto, Nobuo Tsuboi, Takashi Yokoo   +10 more
doaj   +1 more source

Design Engineering of a Bioartificial Renal Tubule Cell Therapy Device

Cell Transplantation, 1999
The use of a bioartificial renal tubule device composed of renal proximal tubule cells grown within a hollow fiber cartridge is a first step in engineering a bioartificial kidney to provide more complete replacement therapy of renal function than is ...
Janeta Nikolovski, Erdogan Gulari, H. David Humes   +2 more
doaj   +1 more source

Bridging Nature and Technology: A Perspective on Role of Machine Learning in Bioinspired Ceramics

Advanced Engineering Materials, EarlyView.
Machine learning (ML) is revolutionizing the development of bioinspired ceramics. This article investigates how ML can be used to design new ceramic materials with exceptional performance, inspired by the structures found in nature. The research highlights how ML can predict material properties, optimize designs, and create advanced models to unlock a ...
Hamidreza Yazdani Sarvestani, Aditi Singh, Behnam Ashrafi   +2 more
wiley   +1 more source

Evaluation of diode laser along with 1.23% acidulated phosphate fluoride gel on dentinal tubule occlusion: An in vitro study

Journal of Indian Society of Periodontology, 2020
Context: Several studies have recommended the use of lasers in treatment of dentinal hypersensitivity. These materials have been used alone or in combination with an active desensitizing agent.
Praveen Jayaram, Amita Olivia Coutinho, Abhishek Bhadranna, Anirban Chatterjee, Vinayak Raghunathan, Faizuddin Imran   +5 more
doaj   +1 more source

Extracorporeal Catalytic Hemoperfusion Therapy for Refractory Septic Shock Using Ceria Nanoparticle‐Embedded Porous Microbeads

Advanced Functional Materials, EarlyView.
This study introduces an extracorporeal hemoperfusion system incorporating porous microbeads embedded with autocatalytic ceria nanoparticles (CeNPs) for targeted reactive oxygen species (ROS) scavenging in septic shock. The blood‐compatible hemoperfusion cartridge demonstrated significant improvements in survival, hemodynamic stability, and organ ...
Pilseon Im, Han‐Gil Jeong, Donghee Kim, Jimin Song, Ngoc Man Phan, Eun‐seo Choi, Young‐Min Kim, Seo‐Hyeon Jeong, Jooho Park, Inwon Park, Jaeyun Kim   +10 more
wiley   +1 more source

Heterogeneity of T-Tubules in Pig Hearts [PDF]

PLOS ONE, 2016
T-tubules are invaginations of the sarcolemma that play a key role in excitation-contraction coupling in mammalian cardiac myocytes. Although t-tubules were generally considered to be effectively absent in atrial myocytes, recent studies on atrial cells from larger mammals suggest that t-tubules may be more numerous than previously supposed.
Gadeberg, Hanne C, Bond, Richard C, Kong, Cherrie, Chanoit, Guillaume, Ascione, Raimondo, Cannell, Mark, James, Andrew   +6 more
openaire   +6 more sources