Results 41 to 50 of about 286,999 (386)
Severity and Frequency of Proximal Tubule Injury Determines Renal Prognosis.
Journal of the American Society of Nephrology, 2016 AKI increases the risk of developing CKD, but the mechanisms linking AKI to CKD remain unclear. Because proximal tubule injury is the mainstay of AKI, we postulated that proximal tubule injury triggers features of CKD. We generated a novel mouse model to
Koji Takaori +12 more
semanticscholar +1 more source
The role of renal proximal tubule transport in the regulation of blood pressure
Kidney Research and Clinical Practice, 2017 The electrogenic sodium/bicarbonate cotransporter 1 (NBCe1) on the basolateral side of the renal proximal tubule plays a pivotal role in systemic acid-base homeostasis.
Shoko Horita +6 more
doaj +1 more source
Kidney & Blood Pressure Research, 2021 Introduction: The diameter and area of the proximal convoluted tubule (PCT) and the distal convoluted tubule (DCT) are of the main parameters analyzed in stereological studies of the kidney.
Marta Ortega-Martinez +5 more
doaj +1 more source
Cardiac T-Tubule Microanatomy and Function.
Physiological Reviews, 2017 Unique to striated muscle cells, transverse tubules (t-tubules) are membrane organelles that consist of sarcolemma penetrating into the myocyte interior, forming a highly branched and interconnected network.
T. Hong, R. Shaw
semanticscholar +1 more source
A Deep Learning Approach for Classification of Dentinal Tubule Occlusions
Applied Artificial Intelligence, 2022 This study aimed to develop a novel deep learning model for reliable quantification of dentinal tubule occlusions instead of manual assessment techniques, and the performance of the model was compared to other methods in the literature. Ninety-six dentin
Anday Duru +3 more
doaj +1 more source
Receptor-Mediated Endocytosis in the Proximal Tubule.
Annual Review of Physiology, 2017 Cells lining the proximal tubule (PT) of the kidney are highly specialized for apical endocytosis of filtered proteins and small bioactive molecules from the glomerular ultrafiltrate to maintain essentially protein-free urine.
Megan L. Eshbach, O. Weisz
semanticscholar +1 more source
Longitudinal tracking of acute kidney injury reveals injury propagation along the nephron
Nature Communications, 2023 Acute kidney injury (AKI) is an important risk factor for chronic kidney disease (CKD), but the underlying mechanisms of failed tubule repair and AKI-CKD transition are incompletely understood.
Luca Bordoni +6 more
doaj +1 more source
Chloride channels in stellate cells are essential for uniquely high secretion rates in neuropeptide-stimulated Drosophila diuresis [PDF]
, 2014 Epithelia frequently segregate transport processes to specific cell types, presumably for improved efficiency and control. The molecular players underlying this functional specialization are of particular interest.
Blumenthal, Edward M. +5 more
core +1 more source
AJP - Renal Physiology, 2017 We have characterized the expression and secretion of the acute kidney injury (AKI) biomarkers insulin-like growth factor binding protein 7 (IGFBP7) and tissue inhibitor of metalloproteinases-2 (TIMP-2) in human kidney epithelial cells in primary cell ...
D. Emlet +8 more
semanticscholar +1 more source
Scissors for autolysosome tubules [PDF]
The EMBO Journal, 2015 Autophagic lysosome reformation (ALR) is a cellular process in which lysosomes are reformed through scission of proto-lysosomes from tubular structures extruded from autolysosomes. Despite recent progress, the molecular mechanism of ALR is far from clear.
Li Yu, Yang Chen
openaire +3 more sources