Results 61 to 70 of about 5,396 (203)

Major revision version 13.0 of the European AIDS Clinical Society guidelines 2025

HIV Medicine, Volume 27, Issue 1, Page 18-32, January 2026.
Abstract Background The European AIDS Clinical Society (EACS) guidelines were revised for the 21st time in 2025, with updates covering all aspects of HIV care. Key Points of the Guidelines Update The structure of the guidelines has been reorganized into two parts: Part I focuses on the management and prevention of HIV and related infections, and Part ...
Juan Ambrosioni, Laura I. Levi, Jasmini Alagaratnam, Abiu Sempere, Andrea Mastrangelo, Paolo Paioni, Cristina Mussini, Catia Marzolini, Susanne Dam Nielsen, Charles Béguelin, Steven Welch, Anna Koval, Luis Mendao, Alasdair Bamford, Alexandra Calmy, Giovanni Guaraldi, Cristiana Oprea, Esteban Martínez, Jürgen K. Rockstroh, The EACS Governing Board   +19 more
wiley   +1 more source

KCNJ16-depleted kidney organoids recapitulate tubulopathy and lipid recovery upon statins treatment

Stem Cell Research & Therapy
Background The KCNJ16 gene has been associated with a novel kidney tubulopathy phenotype, viz. disturbed acid–base homeostasis, hypokalemia and altered renal salt transport.
E. Sendino Garví, G. J. J. van Slobbe, E. A. Zaal, J. H. F. de Baaij, J. G. Hoenderop, R. Masereeuw, M. J. Janssen, A. M. van Genderen   +7 more
doaj   +1 more source

Chemotherapy-induced tubulopathy: a case report series

Frontiers in Nephrology
Acquired tubulopathies are frequently underdiagnosed. They can be characterized by the renal loss of specific electrolytes or organic solutes, suggesting the location of dysfunction.
Mario Alamilla-Sanchez, Juan Daniel Diaz Garcia, Valeria Yanez Salguero, Fleuvier Morales Lopez, Victor Ulloa Galvan, Francisco Velasco Garcia-Lascurain, Benjamin Yama Estrella   +6 more
doaj   +1 more source

Fanconi syndrome accompanied by renal function decline with tenofovir disoproxil fumarate: a prospective, case-control study of predictors and resolution in HIV-infected patients. [PDF]

PLoS ONE, 2014
The predictors of Fanconi syndrome (FS) accompanied by renal function decline with use of the antiretroviral tenofovir disoproxil fumarate (TDF) have not been assessed.
Samir K Gupta, Albert M Anderson, Ramin Ebrahimi, Todd Fralich, Hiba Graham, Valeska Scharen-Guivel, John F Flaherty, Claude Fortin, Robert C Kalayjian, Anita Rachlis, Christina M Wyatt   +10 more
doaj   +1 more source

Transient Renal Tubulopathy: A Case Report

Renal Failure, 2008
A five-year-old boy was evaluated for fever, abdominal pain, vomiting, and diarrhea lasting two days. Chest radiograph revealed a left bronchopneumonia. Metabolic work-up demonstrated phosphaturia, glucosuria, calciuria, proteinuria, profound hypophosphatemia, hypouricemia, borderline hypomagnesemia, and normoglycemia.
Shira, Shacham, Michael, Goldman, Mordechai, Aladjem, Tzvy, Bistritzer   +3 more
openaire   +2 more sources

Combined proximal tubulopathy, crystal-storing histiocytosis, and cast nephropathy in a patient with light chain multiple myeloma

BMC Nephrology, 2017
Background The diagnosis of myeloma, a plasma dyscrasia, often results from the workup of unexplained renal disease. Persistent renal failure in myeloma is commonly caused by tubular nephropathy due to circulating immunoglobulins and free light chains ...
Chung-Kuan Wu, An-Hang Yang, Hung-Chih Lai, Bing-Shi Lin   +3 more
doaj   +1 more source

Clinical Characteristics, Symptoms, and Long-Term Outcomes in Gitelman Syndrome

Kidney International Reports
Introduction: Gitelman syndrome (GS) is a rare inherited salt-losing tubulopathy with limited clinical data. Methods: Surveys were conducted with GS physicians in Europe and patients with GS in the Netherlands to compare findings with the general ...
Michiel L.A.J. Wieërs, Lise Allard, Viola D’Ambrosio, Pedro Arango-Sancho, Jeroen H.F. de Baaij, Francesca Becherucci, Aurelia Bertholet-Thomas, Martine Besouw, Anne Blanchard, Martina Cacciapuoti, Vincenza Carbone, Elisabeth A. Cornelissen, Federico Daffara, Jan Degenhardt, Olivier Devuyst, Eiske Dorresteijn, Rhys Evans, Lucile Figueres, Marc Fila, Marica Giliberti, Valentine Gillion, Sophie Haumann, Gerlineke Hawkins – van der Cingel, Pascal Houillier, Marguerite Hureaux, Felix Knauf, Bertrand Knebelmann, Martin Konrad, Theresa Kwon, Sandrine Lemoine, Germana Longo, Tom Nijenhuis, Rik H.G. Olde Engberink, Hector Ríos Duro, Chloé Saadé, John A. Sayer, Karl-Peter Schlingmann, Thomas Simon, Marijn M. Speeckaert, Hai Liang Tan, Francesco Trepiccione, Rosa Vargas-Poussou, Faidra Veligratti, Stephen B. Walsh, Mahdi Salih, Pedro H. Imenez Silva, Ewout J. Hoorn, Pilar Auñón, Detlef Bockenhauer, Peter J. Conlon, Cosima Erhardt, Sacha Flammier, Cristina Blázquez Gómez, Sercin Guven, Gerlineke Hawkins, Jan Halbritter, Maria Herthelius, Alba Herreros, Dragan Klaric, Nóra Ledó, Pierluigi Marzuillo, Susanne Schäfer, Roland Schmitt, Malgorzata Stanczyk, Francesa Taroni, Nikola Zagorec   +65 more
doaj   +1 more source

Comparison of Two Strategies of Analysis of Urinary Protein Composition for the Diagnosis and Follow‐Up of Renal Diseases

ELECTROPHORESIS, Volume 46, Issue 23, Page 1673-1680, December 2025.
ABSTRACT Proteinuria analysis is necessary to detect the early stages of kidney disease before the estimated glomerular filtration rate deteriorates and to monitor the progression of treated kidney disease. Electrophoresis is often the first orientation test, although this test is time‐consuming and its interpretation may be subjective.
Joris Guyon, Jeanne Malaubier, Hong‐Van Pham, Lila Rami Arab, Laurence Pieroni, Marie‐Laure Curutchet‐Burtin, Rémi Segues, Sylvie Caspar‐Bauguil, Annie M. Bérard   +8 more
wiley   +1 more source

Modulation of renal inflammation and tubular injury by calcitriol in patients with early diabetic kidney disease: a randomized controlled trial

Annals of Medicine
Introduction Diabetic kidney disease (DKD) is marked by inflammation, fibrosis and oxidative stress. Calcitriol may offer renoprotective effects by modulating these processes.
Pringgodigdo Nugroho, Aida Lydia, Pradana Soewondo, Suhardjono, Ina Susianti Timan, Kuntjoro Harimurti, Zulkhair Ali   +6 more
doaj   +1 more source

Supplementation With Curcumin Exhibits Nephroprotective Effects in Cisplatin‐Induced Acute Kidney Injury

Food Science &Nutrition, Volume 13, Issue 12, December 2025.
(By Figdraw, ID: APASW31e60) (37.7 × 60 Mm). This study demonstrates that supplementation with curcumin alleviates cisplatin‐induced kidney injury. It works by restoring mitochondrial balance via the AMPK/PGC‐1α/Sirt3 pathway, reducing oxidative stress and apoptosis through the Nrf2/Keap1 and Bax/Bcl2/Caspase‐3 pathways, and correcting dysfunction in ...
Mingkang Zhang, Yazhi Wang, Xiujuan Wang, Yan Zhou, Yanrong Ma, Xin'an Wu   +5 more
wiley   +1 more source