Results 81 to 90 of about 41,096 (247)

What drives animal responses to high severity fire? The role of functional traits

open access: yesBiological Reviews, Volume 101, Issue 6, Page 2613-2633, December 2026.
ABSTRACT Fire regimes are changing worldwide, with increases in the frequency, extent, and severity of fires posing growing risks to biodiversity. Fire severity – the degree of habitat alteration following fire – strongly influences both immediate survival and long‐term recovery of fauna.
Grace A. Vielleux   +3 more
wiley   +1 more source

Effect of Field Dimension on Energy Expenditure and Exercise Intensity During Walking Football in Older Adults

open access: yesEuropean Journal of Sport Science, Volume 26, Issue 12, December 2026.
ABSTRACT Walking football (WF) is an adapted low‐impact form of traditional football designed to promote physical activity and social interaction among older adults. However, evidence on its physiological demands—particularly energy expenditure expressed in metabolic equivalents (METs)—remains limited.
Silvia Varela   +3 more
wiley   +1 more source

The Scm FCS finger binds the Pcl Tudor domain to link canonical PRC1 and PRC2.1 in Drosophila

open access: yesProtein Science, Volume 35, Issue 12, December 2026.
Abstract Canonical Polycomb Repressive Complex 1 (PRC1) was previously reported to selectively associate with Polycomb Repressive Complex 2.1 (PRC2.1) in cross‐linking‐based affinity purification experiments from Drosophila embryos, but the molecular basis of this interaction has remained unresolved.
Berfin Yesil   +3 more
wiley   +1 more source

A New Recruitable E3 Ligase UHRF1 Supporting Targeted Protein Degradation: A Minimal Azide as a Recruitment Ligand

open access: yesAdvanced Science, Volume 13, Issue 62, 9 November 2026.
Targeted protein degradation is often limited by the scarcity of usable E3 ligases. Herein, we report the first small‐molecule GPX4 degraders that incorporate either electrophilic warheads or a minimal azide group as an E3 recruitment ligand. The azide‐based degrader DK‐5070 effectively drives potent GPX4 degradation; mechanistic studies reveal that ...
Zehong Lin   +14 more
wiley   +1 more source

Tudor

open access: yes, 2008
Biblioteca de Educación del Ministerio de Educación, Cultura y Deporte; Calle San Agustín, 5 - 3 planta; 28014 Madrid; Tel.
openaire   +1 more source

RSF1‐Dependent PAR Turnover Promotes 53BP1 Liquid Condensate Formation at DNA Damage Sites

open access: yesAdvanced Science, Volume 13, Issue 63, 12 November 2026.
At sites of DNA damage, RSF1 recruits PARG to accelerate PAR turnover, triggering a switch from PAR‐driven condensates to 53BP1 condensates. This condensate transition enables p53‐dependent gene transcription and coordinates the DNA damage response.
Yungyeong Heo   +10 more
wiley   +1 more source

Loss of CYLD on Chromosome 16q Impairs Homologous Recombination and Genomic Stability Through TIRR Degradation

open access: yesAdvanced Science, Volume 13, Issue 62, 9 November 2026.
Chromosome 16q loss drives genomic instability through disruption of the CYLD–TIRR–53BP1 axis. CYLD preserves homologous recombination by stabilizing TIRR and limiting 53BP1 accumulation at DNA double‐strand breaks. CYLD deficiency redirects repair toward error‐prone non‐homologous end joining, promotes mutational burden and homologous recombination ...
Mingming Lu   +14 more
wiley   +1 more source

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