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Decisive role of brain biopsy in atypical tumefactive demyelinating lesions: A case report [PDF]

Radiology Case Reports
In neuroimaging, tumefactive demyelinating lesions (TDLs), which are rare inflammatory lesions of the central nervous system, can sometimes resemble infectious or malignant processes. Radiologic distinction is frequently made more difficult by their huge
Nazlı Gamze Bülbül, MD, Asel Jusupova, MD, Buse Gül Belen, MD, Başak Ceren Okcu Korkmaz, MD, Fatma Sibel Bayramoğlu, MD, Mehmet Fatih Özdağ, MD, Rıfat Erdem Toğrol, MD, Aydın Sav, MD, Aksel Siva, MD   +8 more
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Giant tumefactive perivascular spaces

Radiology Case Reports, 2023
Perivascular spaces are parts of the glymphatic pathway in the brain, which are microscopic but visible on magnetic resonance imaging when enlarged. Here, we described a case of a 16-year-old boy who presented with chronic headaches.
Xiaodi Hao, PhD, Mingfang Zhu, MD, Leilei Tan, MD, Yue Huang, PhD, Jiewen Zhang, PhD   +4 more
doaj   +5 more sources

Paraneoplastic Tumefactive Demyelination With Underlying Anaplastic Thyroid Cancer: A Case Report and Review of the Literature [PDF]

Journal of Central Nervous System Disease
We present a case of paraneoplastic tumefactive demyelination in a 55-year-old female with an underlying anaplastic thyroid carcinoma (ATC), alongside a review of the literature on all cases of tumefactive demyelination associated with non-CNS neoplasia.
Chaloulos-Iakovidis Panagiotis, Arsany Hakim, Stork Lidia, Stadelmann-Nessler Christine, Kollár Attila, Chan Andrew, De Beukelaer Sophie, Salmen Anke, Hoepner Robert, Helly Hammer   +9 more
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Cerebellar tumefactive demyelination in MOGAD: a case report on diagnostic challenges and immunotherapeutic strategy [PDF]

Frontiers in Immunology
Tumefactive demyelination is a rare phenotypic subtype of myelin oligodendrocyte glycoprotein (MOG) antibody-associated disease (MOGAD) and poses significant diagnostic challenges due to substantial clinical and radiological overlap with intracranial ...
XiaoDan Zheng, JiaYue Zhang, DaWei Li, Bo Yuan   +3 more
doaj   +2 more sources

A case of retinal vasculopathy with cerebral leukoencephalopathy and systemic manifestations [PDF]

Radiology Case Reports
Retinal vasculopathy with cerebral leukoencephalopathy (RVCL) is an autosomal dominant disorder caused by mutations in the TREX1 gene, which affects medium and small arteries and veins. Reported in fewer than 50 families worldwide, RVCL typically affects
Musharaf Khan, DO, Subtain Ali, MD, Bushra Sayeed, MD, Eyassu Hailemichael, MD, Dhairya A. Lakhani, MD   +4 more
doaj   +2 more sources

Identifying Tumefactive Demyelination on Synthetic MRI Myelin Maps [PDF]

Case Reports in Radiology
Tumefactive demyelinating lesions and brain neoplasms often present as a diagnostic challenge due to overlapping radiographic features among conventional imaging modalities ultimately resulting in uncertainty if a biopsy is warranted to establish a ...
Brandon Simons, Rebecca Li, Tushar Chandra, Laura Hayes   +3 more
doaj   +2 more sources

A case report and literature review on giant tumefactive perivascular spaces [PDF]

Frontiers in Neuroscience
BackgroundPerivascular spaces (PVS) are fluid-filled cavities located in the brain that surround blood vessels. Dilated PVS (dPVS) can be discerned on MRI in healthy individuals.
Chang Cheng, Yiqi Pan, Ke Ma, Shuhan Liu, Xiaoli Mai, Xiaoli Mai, Xiaoli Mai   +6 more
doaj   +2 more sources

Tumefactive multiple sclerosis: the lethal chameleon [PDF]

European Journal of Case Reports in Internal Medicine
Tumefactive multiple sclerosis (TMS) is a rare variant of multiple sclerosis that presents with a large demyelinating lesion in the central nervous system, accompanied by peripheral ring-like enhancement, perilesional oedema and mass effect.
Ana Carolina Monteiro, Tomás França de Santana, Carolina Chumbo, Catarina Negrão, Teresa Valido, Filipa Figueiredo, Clara Matos   +6 more
doaj   +2 more sources

Pediatric tumefactive multiple sclerosis - a challenging case [PDF]

Romanian Journal of Neurology, 2014
Multiple sclerosis (MS) is an autoimmune inflammatory disease of the central nervous system which is often diagnosed in young adults. We present a case of tumefactive multiple sclerosis in a child, an unusual form of presentation of MS, especially at ...
Smaranda Nita, Diana Epure, Magdalena Sandu, Daniel Teleanu, Raluca Teleanu   +4 more
doaj   +1 more source

Recurrent tumefactive demyelinating lesions in an elderly woman

Radiology Case Reports, 2022
Here we describe a 72-year old Caucasian woman who presented with progressive left hemiparesis and hemisensory deficits due to a pathology-confirmed tumefactive demyelinating lesion in the right frontoparietal region.
Erika L. Weil, MD, Mohammad Obadah Nakawah, MD   +1 more
doaj   +1 more source